Cellular and molecular mechanisms of endothelial dysfunction in diabetes (Q38134022)

29 August 2017

Cellular and molecular mechanisms of endothelial dysfunction in diabetes (English)

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29 August 2017

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2

Karen E Porter

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author name string

Anna C Roberts

series ordinal

1

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PubMed ID

24002671

29 August 2017

language of work or name

English

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publication date

3 September 2013

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PubMed ID

24002671

full work available at URL

29 August 2017

http://eprints.whiterose.ac.uk/77134/

content deliverer

White Rose Research Online

object has role

postprint

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published in

Diabetes and Vascular Disease Research

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29 August 2017

10

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29 August 2017

6

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29 August 2017

472-482

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Dietary energy density predicts the risk of incident type 2 diabetes: the European Prospective Investigation of Cancer (EPIC)-Norfolk Study

29 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Molecular insights and therapeutic targets for diabetic endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Endothelial cell functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Shear stress-induced release of nitric oxide from endothelial cells grown on beads

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

The importance of endothelin-1 for vascular dysfunction in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Cells in focus: endothelial cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Evidence of endothelial dysfunction in angiographically normal coronary arteries of patients with coronary artery disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Impaired muscarinic endothelium-dependent relaxation and cyclic guanosine 5'-monophosphate formation in atherosclerotic human coronary artery and rabbit aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Atherosclerosis impairs endothelium-dependent vascular relaxation to acetylcholine and thrombin in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

The clinical implications of endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Non-invasive evaluation of endothelial dysfunction in uncomplicated obesity: relationship with insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Metabolic syndrome, insulin resistance, and brachial artery vasodilator function in Framingham Offspring participants without clinical evidence of cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Critical nodes in signalling pathways: insights into insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Inhibition of phosphatidylinositol 3-kinase enhances mitogenic actions of insulin in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Pathophysiological implications of insulin resistance on vascular endothelial function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Mechanisms of diabetic complications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

The role of TNF alpha in adipocyte metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Mechanisms of Disease: endothelial dysfunction in insulin resistance and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Nitric oxide and peroxynitrite in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Augmentation of vascular remodeling by uncoupled endothelial nitric oxide synthase in a mouse model of diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Reduction of insulin-stimulated glucose uptake by peroxynitrite is concurrent with tyrosine nitration of insulin receptor substrate-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Superoxide dismutase entrapped-liposomes restore the impaired endothelium-dependent relaxation of resistance arteries in experimental diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Effects of vitamin E on cardiovascular and microvascular outcomes in high-risk patients with diabetes: results of the HOPE study and MICRO-HOPE substudy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

The role of protein kinase C activation and the vascular complications of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Proatherosclerotic mechanisms involving protein kinase C in diabetes and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Selective PKC beta inhibition with ruboxistaurin and endothelial function in type-2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Mechanisms underlying endothelial dysfunction in diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Inhibition of protein kinase Cbeta prevents impaired endothelium-dependent vasodilation caused by hyperglycemia in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Inhibition of protein kinase Cbeta does not improve endothelial function in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Biochemistry and molecular cell biology of diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Advanced glycation end products: sparking the development of diabetic vascular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Intensive Diabetes Treatment and Cardiovascular Disease in Patients with Type 1 Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Overexpression of fibronectin induced by diabetes or high glucose: phenomenon with a memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Progression of incipient diabetic retinopathy during good glycemic control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Resistance of retinal inflammatory mediators to suppress after reinstitution of good glycemic control: novel mechanism for metabolic memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Epigenetic mechanisms in diabetic vascular complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

DNA hypomethylation and methyltransferase expression in atherosclerotic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

The cell-specific expression of endothelial nitric-oxide synthase: a role for DNA methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

21 January 2018

T2DM: Why Epigenetics?

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Hypermethylation of hepatic glucokinase and L-type pyruvate kinase promoters in high-fat diet-induced obese rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

MicroRNA-320 expression in myocardial microvascular endothelial cells and its relationship with insulin-like growth factor-1 in type 2 diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Deregulation of microRNA-503 contributes to diabetes mellitus-induced impairment of endothelial function and reparative angiogenesis after limb ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

MIR221/MIR222-driven post-transcriptional regulation of P27KIP1 and P57KIP2 is crucial for high-glucose- and AGE-mediated vascular cell damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Cell-specific effects of miR-221/222 in vessels: molecular mechanism and therapeutic application

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

MicroRNA-221 regulates high glucose-induced endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

miR-126 regulates angiogenic signaling and vascular integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

microRNA-222 controls neovascularization by regulating signal transducer and activator of transcription 5A expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

MicroRNA-21 exhibits antiangiogenic function by targeting RhoB expression in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Role of microRNAs in diabetes and its cardiovascular complications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Serum microRNAs are promising novel biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

New avenues for the pharmacological management of type 2 diabetes: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Cardiovascular outcomes in trials of oral diabetes medications: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Hypoglycemia, diabetes, and cardiovascular events

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Rosiglitazone revisited: an updated meta-analysis of risk for myocardial infarction and cardiovascular mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

Inherent differences in morphology, proliferation, and migration in saphenous vein smooth muscle cells cultured from nondiabetic and Type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1479164113500680

21 January 2018

Identifiers

DOI

10.1177/1479164113500680

1 reference

Dimensions Publication ID

29 August 2017

10.1177/1479164113500680

0 references

0 references

1 reference

PubMed ID

24002671