Combating multidrug-resistant bacteria: current strategies for the discovery of novel antibacterials (Q38137920)

29 August 2017

title

Combating multidrug-resistant bacteria: current strategies for the discovery of novel antibacterials (English)

1 reference

29 August 2017

main subject

multiple drug resistance

1 reference

6

1 reference

29 August 2017

James T Hodgkinson

2

0 references

Martin Welch

series ordinal

4

object named as

Martin Welch

1 reference

29 August 2017

1

Kieron M G O'Connell

1 reference

29 August 2017

5

George P C Salmond

1 reference

29 August 2017

Hannah F Sore

3

1 reference

29 August 2017

language of work or name

English

0 references

publication date

5 September 2013

1 reference

Angewandte Chemie International Edition

29 August 2017

published in

0 references

volume

52

1 reference

29 August 2017

issue

41

1 reference

29 August 2017

page(s)

10706-10733

1 reference

The composition of Ehrlich's salvarsan: resolution of a century-old debate

29 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antibacterial discovery and development--the failure of success?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Challenges in antimicrobial drug discovery and the potential of nucleoside antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Late stage antibacterial drugs in the clinical pipeline

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antibacterial drug discovery: is it all downhill from here?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Trends in antimicrobial drug development: implications for the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antibiotics for emerging pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Discovering new antimicrobial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

The antibiotic R&D pipeline: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

The crisis in antibiotic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

The future challenges facing the development of new antimicrobial drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

How antibiotics kill bacteria: from targets to networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

The antibiotic resistome: the nexus of chemical and genetic diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Molecular mechanisms of antibacterial multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

R-factor Mediated Dihydrofolate Reductases which Confer Trimethoprim Resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

21 January 2018

Antibiotic efflux pumps

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

The beta-lactamases of gram-negative bacteria and their role in resistance to beta-lactam antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

More extended-spectrum beta-lactamases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Origins and evolution of antibiotic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antibiotic resistance: the perfect storm

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antibiotic resistance is ancient

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antibiotic resistance is ancient: implications for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Renaissance in antibacterial discovery from actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Targeting virulence: a new paradigm for antimicrobial therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Humans as the world's greatest evolutionary force

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

New antibiotics from bacterial natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Abyssomicin C-A polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Abyssomicins, inhibitors of the para-aminobenzoic acid pathway produced by the marine Verrucosispora strain AB-18-032.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Search and discovery strategies for biotechnology: the paradigm shift

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Measurement of in situ activities of nonphotosynthetic microorganisms in aquatic and terrestrial habitats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Uncultured microorganisms as a source of secondary metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Isolating "uncultivable" microorganisms in pure culture in a simulated natural environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Recent developments towards the heterologous expression of complex bacterial natural product biosynthetic pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Codon bias and heterologous protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

A new enzyme superfamily - the phosphopantetheinyl transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Structural and functional analysis of pantocin A: an antibiotic from Pantoea agglomerans discovered by heterologous expression of cloned genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

The soil metagenome--a rich resource for the discovery of novel natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Drugs from hidden bugs: their discovery via untapped resources

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Drug discovery from uncultivable microorganisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Recent application of metagenomic approaches toward the discovery of antimicrobials and other bioactive small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Molecular biological access to the chemistry of unknown soil microbes: a new frontier for natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Cloning and heterologous expression of isocyanide biosynthetic genes from environmental DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Isolation of antibiotics turbomycin a and B from a metagenomic library of soil microbial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Insights into antibiotic resistance through metagenomic approaches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Biosynthesis and mode of action of lantibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Lantibiotics: peptides of diverse structure and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Biosynthesis of the class III lantipeptide catenulipeptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Prepeptide sequence of epidermin, a ribosomally synthesized antibiotic with four sulphide-rings

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Feglymycin, a novel inhibitor of the replication of the human immunodeficiency virus. Fermentation, isolation and structure elucidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Heterologous production of the lantibiotic Ala(0)actagardine in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Organization of the biosynthetic genes encoding deoxyactagardine B (DAB), a new lantibiotic produced by Actinoplanes liguriae NCIMB41362.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Entianin, a novel subtilin-like lantibiotic from Bacillus subtilis subsp. spizizenii DSM 15029T with high antimicrobial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Curvopeptin: a new lanthionine-containing class III lantibiotic and its co-substrate promiscuous synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Structural characterization of four prochlorosins: a novel class of lantipeptides produced by planktonic marine cyanobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Characterization of new class III lantibiotics--erythreapeptin, avermipeptin and griseopeptin from Saccharopolyspora erythraea, Streptomyces avermitilis and Streptomyces griseus demonstrates stepwise N-terminal leader processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Labyrinthopeptins: a new class of carbacyclic lantibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Evaluation of NVB302 versus vancomycin activity in an in vitro human gut model of Clostridium difficile infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antibakterielle Naturstoffe in der medizinischen Chemie – Exodus oder Renaissance?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antibacterial natural products in medicinal chemistry--exodus or revival?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Molecular structures of penicillin-binding proteins and beta-lactamases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Cephalosporins in clinical development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Ceftaroline fosamil: a new broad-spectrum cephalosporin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Ceftobiprole: a new option for treatment of skin and soft-tissue infections due to methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

In vitro and in vivo properties of Ro 63-9141, a novel broad-spectrum cephalosporin with activity against methicillin-resistant staphylococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Ceftaroline: a novel cephalosporin with activity against methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

TAK-599, a novel N-Phosphono type prodrug of anti-MRSA cephalosporin T-91825: synthesis, physicochemical and pharmacological properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Beta-lactams against methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Affinity of ceftaroline and other beta-lactams for penicillin-binding proteins from Staphylococcus aureus and Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

An acquired and a native penicillin-binding protein cooperate in building the cell wall of drug-resistant staphylococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

A randomized, double-blind trial comparing ceftobiprole medocaril with vancomycin plus ceftazidime for the treatment of patients with complicated skin and skin-structure infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Structural Insights into the Anti-methicillin-resistant Staphylococcus aureus (MRSA) Activity of Ceftobiprole

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Co-opting the cell wall in fighting methicillin-resistant Staphylococcus aureus: potent inhibition of PBP 2a by two anti-MRSA beta-lactam antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Vancomycin resistance in gram-positive cocci

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

The Vancomycin Group of Antibiotics and the Fight against Resistant Bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Glycopeptide and lipoglycopeptide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

VanA-type vancomycin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Partitioning the loss in vancomycin binding affinity for D-Ala-D-Lac into lost H-bond and repulsive lone pair contributions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Redesign of glycopeptide antibiotics: back to the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Total synthesis and evaluation of [Psi[CH2NH]Tpg4]vancomycin aglycon: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

A redesigned vancomycin engineered for dual D-Ala-D-ala And D-Ala-D-Lac binding exhibits potent antimicrobial activity against vancomycin-resistant bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Total synthesis of [Ψ[C(═S)NH]Tpg4]vancomycin aglycon, [Ψ[C(═NH)NH]Tpg4]vancomycin aglycon, and related key compounds: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Activities of the semisynthetic glycopeptide LY191145 against vancomycin-resistant enterococci and other gram-positive bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Effect of LY333328 against vancomycin-resistant Enterococcus faecium in a rat central venous catheter-associated infection model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Mechanism of action of oritavancin and related glycopeptide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Worldwide assessment of dalbavancin activity and spectrum against over 6,000 clinical isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Tolerability, pharmacokinetics, and serum bactericidal activity of intravenous dalbavancin in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Dalbavancin: a novel antimicrobial

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Semi-synthetic glycopeptide antibacterials

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Telavancin, a multifunctional lipoglycopeptide, disrupts both cell wall synthesis and cell membrane integrity in methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Telavancin disrupts the functional integrity of the bacterial membrane through targeted interaction with the cell wall precursor lipid II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Mechanisms of action of cephalosporin 3'-quinolone esters, carbamates, and tertiary amines in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

In vitro evaluation of CBR-2092, a novel rifamycin-quinolone hybrid antibiotic: studies of the mode of action in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

In vitro evaluation of CBR-2092, a novel rifamycin-quinolone hybrid antibiotic: microbiology profiling studies with staphylococci and streptococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Synthesis of substituted 6-anilinouracils and their inhibition of DNA polymerase IIIC and Gram-positive bacterial growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Synthesis and antibacterial activity of 3-substituted-6-(3-ethyl-4-methylanilino)uracils

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antibacterial activity and mechanism of action of a novel anilinouracil-fluoroquinolone hybrid compound

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Hybrid antibacterials. DNA polymerase-topoisomerase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Design, synthesis, and evaluation of novel fluoroquinolone-aminoglycoside hybrid antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Molecular insights into aminoglycoside action and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Chemistry and biology of siderophores

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Exploiting bacterial iron acquisition: siderophore conjugates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Iron transport-mediated drug delivery: practical syntheses and in vitro antibacterial studies of tris-catecholate siderophore-aminopenicillin conjugates reveals selectively potent antipseudomonal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antimicrobial peptides of multicellular organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antibacterial peptides for therapeutic use: obstacles and realistic outlook

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

The relationship between peptide structure and antibacterial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Multifunctional cationic host defence peptides and their clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Structure and mechanism of action of an indolicidin peptide derivative with improved activity against gram-positive bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Sublethal concentrations of pleurocidin-derived antimicrobial peptides inhibit macromolecular synthesis in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

The co-evolution of host cationic antimicrobial peptides and microbial resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antimicrobial peptide therapeutics for cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Experimental evolution of resistance to an antimicrobial peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Induced resistance to the antimicrobial peptide lactoferricin B in Staphylococcus aureus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Resistance to antimicrobial peptides in Gram-negative bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Potential of old-generation antibiotics to address current need for new antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Intravenous colistin sulphomethate in acute respiratory exacerbations in adult patients with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Cationic antimicrobial peptides in clinical development, with special focus on thanatin and heliomicin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Beyond natural antimicrobial peptides: multimeric peptides and other peptidomimetic approaches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antimicrobial peptide mimics for improved therapeutic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Impact of self-assembly properties on antibacterial activity of short acyl-lysine oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Structure-activity relationships of antibacterial acyl-lysine oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Improved antimicrobial peptides based on acyl-lysine oligomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Mechanisms mediating bactericidal properties and conditions that enhance the potency of a broad-spectrum oligo-acyl-lysyl

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Experimental conditions that enhance potency of an antibacterial oligo-acyl-lysyl

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Dual mechanism of bacterial lethality for a cationic sequence-random copolymer that mimics host-defense antimicrobial peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Antibacterial agents based on the cyclic D,L-alpha-peptide architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Systemic antibacterial activity of novel synthetic cyclic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

The world of beta- and gamma-peptides comprised of homologated proteinogenic amino acids and other components

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

De novo design, synthesis, and characterization of antimicrobial beta-peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Use of parallel synthesis to probe structure-activity relationships among 12-helical beta-peptides: evidence of a limit on antimicrobial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Effect of sequence and structural properties on 14-helical beta-peptide activity against Candida albicans planktonic cells and biofilms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Structure-activity studies of 14-helical antimicrobial beta-peptides: probing the relationship between conformational stability and antimicrobial potency

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Mimicry of host-defense peptides by unnatural oligomers: antimicrobial beta-peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Jamming bacterial communication: new approaches for the treatment of infectious diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Quorum-sensing signal binding results in dimerization of TraR and its release from membranes into the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

A novel strategy for the isolation of luxI homologues: evidence for the widespread distribution of a LuxR:LuxI superfamily in enteric bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Promoter specificity in Pseudomonas aeruginosa quorum sensing revealed by DNA binding of purified LasR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Global position analysis of the Pseudomonas aeruginosa quorum-sensing transcription factor LasR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Quorum sensing and social networking in the microbial world.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Control of bioluminescence in Vibrio fischeri by the LuxO signal response regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

An agr quorum sensing system that regulates granulose formation and sporulation in Clostridium acetobutylicum

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Identification of genes controlled by quorum sensing in Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Isolation and characterization of an autoinducer synthase from Acinetobacter baumannii

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Microbial quorum sensing: a tool or a target for antimicrobial therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Multiple N-acyl-L-homoserine lactone signal molecules regulate production of virulence determinants and secondary metabolites in Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Quorum sensing in Gram-negative bacteria: small-molecule modulation of AHL and AI-2 quorum sensing pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Proteomics of the bacterial cross-talk by quorum sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Quenching the quorum sensing system: potential antibacterial drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Transient interference with staphylococcal quorum sensing blocks abscess formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Quorum quenching quandary: resistance to antivirulence compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Applications of small molecule activators and inhibitors of quorum sensing in Gram-negative bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Recent progresses on AI-2 bacterial quorum sensing inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Burkholderia pseudomallei, B. thailandensis, and B. ambifaria produce 4-hydroxy-2-alkylquinoline analogues with a methyl group at the 3 position that is required for quorum-sensing regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Quinolones: from antibiotics to autoinducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density-dependency of the quorum sensing hierarchy, regulates rhl-dependent genes at the onset of stationary phase and can be produced in the absence of LasR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Structural requirements of the Pseudomonas quinolone signal for membrane vesicle stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Functions required for extracellular quinolone signaling by Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Oxygen levels rapidly modulate Pseudomonas aeruginosa social behaviours via substrate limitation of PqsH

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Structure elucidation and preliminary assessment of hydrolase activity of PqsE, the Pseudomonas quinolone signal (PQS) response protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Microwave and flow syntheses of Pseudomonasquinolone signal (PQS) and analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Structure-activity analysis of the Pseudomonas quinolone signal molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Discovery of antagonists of PqsR, a key player in 2-alkyl-4-quinolone-dependent quorum sensing in Pseudomonas aeruginosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Identification of small-molecule antagonists of the Pseudomonas aeruginosa transcriptional regulator PqsR: biophysically guided hit discovery and optimization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Pseudomonas aeruginosa PqsA is an anthranilate-coenzyme A ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Interference with Pseudomonas quinolone signal synthesis inhibits virulence factor expression by Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Inhibitors of pathogen intercellular signals as selective anti-infective compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Indole and 7-hydroxyindole diminish Pseudomonas aeruginosa virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Bicyclic compounds repress membrane vesicle production and Pseudomonas quinolone signal synthesis in Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Dioxygenase-mediated quenching of quinolone-dependent quorum sensing in Pseudomonas aeruginosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Inhibition of cytochrome systems of heart muscle and certain bacteria by the antagonists of dihydrostreptomycin: 2-alkyl-4-hydroxyquinoline N-oxides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Defining the mode of action of tetramic acid antibacterials derived from Pseudomonas aeruginosa quorum sensing signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

The effect of a cell-to-cell communication molecule, Pseudomonas quinolone signal (PQS), produced by P. aeruginosa on other bacterial species

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

The Pseudomonas quinolone signal (PQS), and its precursor HHQ, modulate interspecies and interkingdom behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Identification of Staphylococcus aureus AgrD residues required for autoinducing peptide biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Transmembrane topology and histidine protein kinase activity of AgrC, the agr signal receptor in Staphylococcus aureus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Staphylococcus aureus AgrA binding to the RNAIII-agr regulatory region

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Expression of virulence factors by Staphylococcus aureus grown in serum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Bacterial interference caused by autoinducing peptide variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Structure-activity analysis of synthetic autoinducing thiolactone peptides from Staphylococcus aureus responsible for virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Identification of ligand specificity determinants in AgrC, the Staphylococcus aureus quorum-sensing receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Side-chain-to-tail thiolactone peptide inhibitors of the staphylococcal quorum-sensing system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Structure, activity and evolution of the group I thiolactone peptide quorum-sensing system of Staphylococcus aureus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Turning virulence on and off in staphylococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Rational design of a global inhibitor of the virulence response in Staphylococcus aureus, based in part on localization of the site of inhibition to the receptor-histidine kinase, AgrC

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Virulence regulation and quorum sensing in staphylococcal infections: competitive AgrC antagonists as quorum sensing inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Design and synthesis of macrocyclic peptomers as mimics of a quorum sensing signal from Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Inhibition of virulence gene expression in Staphylococcus aureus by novel depsipeptides from a marine photobacterium

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Discovery of a quorum-sensing inhibitor of drug-resistant staphylococcal infections by structure-based virtual screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Ambuic acid inhibits the biosynthesis of cyclic peptide quormones in gram-positive bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Modulating immunity as a therapy for bacterial infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Microwave-assisted preparation of the quorum-sensing molecule 2-heptyl-3-hydroxy-4(1H)-quinolone and structurally related analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

Glycopeptide Antibiotic Activity and the Possible Role of Dimerization: A Model for Biological Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201209979

21 January 2018

Identifiers

DOI

10.1002/ANIE.201209979

1 reference

29 August 2017

1 reference