Proteomic identification of protease cleavage sites: cell-biological and biomedical applications (Q38151761)

29 August 2017

title

Proteomic identification of protease cleavage sites: cell-biological and biomedical applications (English)

1 reference

29 August 2017

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117201%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Hasmik Shahinian

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117201%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Stefan Tholen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117201%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

1 October 2013

1 reference

Expert Review of Proteomics

29 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117201%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117201%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117201%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

421-433

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117201%20AND%20SRC:MED&resulttype=core&format=json

Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3

1 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Dipeptidylpeptidase 4 negatively regulates colony-stimulating factor activity and stress hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

ADAM17: a molecular switch to control inflammation and tissue regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

The Degradome database: mammalian proteases and diseases of proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Protease degradomics: mass spectrometry discovery of protease substrates and the CLIP-CHIP, a dedicated DNA microarray of all human proteases and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Tissue inhibitors of metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

The cystatins: Protein inhibitors of cysteine proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

In search of partners: linking extracellular proteases to substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

The design of drugs for HIV and HCV

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Functional characterization of the Mycobacterium tuberculosis zinc metallopeptidase Zmp1 and identification of potential substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Global profiling of proteolysis during rupture of Plasmodium falciparum from the host erythrocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Falcipains and other cysteine proteases of malaria parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

The discovery and development of rivaroxaban, an oral, direct factor Xa inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Aliskiren: the first renin inhibitor for clinical treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Drugs targeting the renin-angiotensin-aldosterone system

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Incretin-based therapies for type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Discovery and development of telaprevir: an NS3-4A protease inhibitor for treating genotype 1 chronic hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Inhibition of cathepsin K for treatment of osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

The development of proteasome inhibitors as anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Targeting proteases: successes, failures and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Protease degradomics: a new challenge for proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Trypsin cleaves exclusively C-terminal to arginine and lysine residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Serine proteases of the classical and lectin pathways: similarities and differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Determination of protease cleavage site motifs using mixture-based oriented peptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

A quantitative proteomics design for systematic identification of protease cleavage events.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Proteomic identification of protease cleavage sites characterizes prime and non-prime specificity of cysteine cathepsins B, L, and S.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

PoPS: a computational tool for modeling and predicting protease specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Prediction of protease substrates using sequence and structure features

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Toward computer-based cleavage site prediction of cysteine endopeptidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Characterization of the prime and non-prime active site specificities of proteases by proteome-derived peptide libraries and tandem mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Proteomic analyses reveal an acidic prime side specificity for the astacin metalloprotease family reflected by physiological substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Proteomic techniques and activity-based probes for the system-wide study of proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Proteomic discovery of protease substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

NSP4, an elastase-related protease in human neutrophils with arginine specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

High resolution analysis of snake venom metalloproteinase (SVMP) peptide bond cleavage specificity using proteome based peptide libraries and mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Factor Xa subsite mapping by proteome-derived peptide libraries improved using WebPICS, a resource for proteomic identification of cleavage sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Proteome-derived peptide libraries to study the substrate specificity profiles of carboxypeptidases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Quantitative protease cleavage site profiling using tandem-mass-tag labeling and LC-MALDI-TOF/TOF MS/MS analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Global identification of peptidase specificity by multiplex substrate profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Human and mouse proteases: a comparative genomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Characterization of the substrate specificity of human carboxypeptidase A4 and implications for a role in extracellular peptide processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

A lead discovery strategy driven by a comprehensive analysis of proteases in the peptide substrate space

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

N- and C-terminal degradomics: new approaches to reveal biological roles for plant proteases from substrate identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Profiling protease activities by dynamic proteomics workflows

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Mass spectrometry-based proteomics strategies for protease cleavage site identification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Methods for mapping protease specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

A proteomic approach to identify substrates of matrix metalloproteinase-14 in human plasma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Identification of caspase-3 degradome by two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionization-time of flight analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

A proteomic approach for the discovery of protease substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Shotgun proteome analysis of protein cleavage in apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Global mapping of the topography and magnitude of proteolytic events in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Identification of beta-secretase (BACE1) substrates using quantitative proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

A SILAC-based approach identifies substrates of caspase-dependent cleavage upon TRAIL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Profiling constitutive proteolytic events in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Chemoenzymatic labeling of protein C-termini for positive selection of C-terminal peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Unbiased selective isolation of protein N-terminal peptides from complex proteome samples using phospho tagging (PTAG) and TiO(2)-based depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Systems-level analysis of proteolytic events in increased vascular permeability and complement activation in skin inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Complementary positional proteomics for screening substrates of endo- and exoproteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Proteome-wide analysis of protein carboxy termini: C terminomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

A method for the isolation of blocked N-terminal peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Isolation of N-terminal protein sequence tags from cyanogen bromide cleaved proteins as a novel approach to investigate hydrophobic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Positional proteomics: selective recovery and analysis of N-terminal proteolytic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Selective isolation of N-blocked peptides by isocyanate-coupled resin

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

In vacuo isotope coded alkylation technique (IVICAT); an N-terminal stable isotopic label for quantitative liquid chromatography/mass spectrometry proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Global kinetic analysis of proteolysis via quantitative targeted proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Comparative assessment of large-scale proteomic studies of apoptotic proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Mechanistic insight into taxol-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Proteome-wide substrate analysis indicates substrate exclusion as a mechanism to generate caspase-7 versus caspase-3 specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Proteome-wide Identification of HtrA2/Omi Substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Inflammatory stimuli regulate caspase substrate profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Identification of proteolytic cleavage sites by quantitative proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Functional interplay between caspase cleavage and phosphorylation sculpts the apoptotic proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

21 January 2018

The N-end rule pathway

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Multiplex N-terminome analysis of MMP-2 and MMP-9 substrate degradomes by iTRAQ-TAILS quantitative proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

A statistics-based platform for quantitative N-terminome analysis and identification of protease cleavage products

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Biochemical characterization and N-terminomics analysis of leukolysin, the membrane-type 6 matrix metalloprotease (MMP25): chemokine and vimentin cleavages enhance cell migration and macrophage phagocytic activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Specialized roles for cysteine cathepsins in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Identifying natural substrates for dipeptidyl peptidases 8 and 9 using terminal amine isotopic labeling of substrates (TAILS) reveals in vivo roles in cellular homeostasis and energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Death by a thousand cuts: granzyme pathways of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Granzyme K displays highly restricted substrate specificity that only partially overlaps with granzyme A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

The substrate specificity profile of human granzyme A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Selective chemical functional probes of granzymes A and B reveal granzyme B is a major effector of natural killer cell-mediated lysis of target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Granzyme M is a regulatory protease that inactivates proteinase inhibitor 9, an endogenous inhibitor of granzyme B

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Human and mouse granzyme M display divergent and species-specific substrate specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Probing the efficiency of proteolytic events by positional proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Proteomic analysis of the coagulation reaction in plasma and whole blood using PROTOMAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Sampling the N-terminal proteome of human blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Differential exoprotease activities confer tumor-specific serum peptidome patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Membrane protease proteomics: Isotope-coded affinity tag MS identification of undescribed MT1-matrix metalloproteinase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

A proteomic approach for the identification of cell-surface proteins shed by metalloproteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Selective enrichment of newly synthesized proteins for quantitative secretome analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Urinary proteome analysis for prostate cancer diagnosis: cost-effective application in routine clinical practice in Germany

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Markers of vascular disease in plasma from patients with chronic kidney disease identified by proteomic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Peptidomics of Cpe(fat/fat) mouse brain regions: implications for neuropeptide processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Quantitative neuropeptidomics of microwave-irradiated mouse brain and pituitary

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Peptidomics of Cpe fat/fat mouse hypothalamus: effect of food deprivation and exercise on peptide levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Quantitative peptidomics of mouse pituitary: comparison of different stable isotopic tags

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

A large and accurate collection of peptidase cleavages in the MEROPS database

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

MEROPS: the peptidase database

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

TopFIND, a knowledgebase linking protein termini with function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

The DegraBase: a database of proteolysis in healthy and apoptotic human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Proteomics discovery of metalloproteinase substrates in the cellular context by iTRAQ labeling reveals a diverse MMP-2 substrate degradome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

Urinary Proteome Analysis to Exclude Severe Vesicoureteral Reflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2013.841547

10.1586/14789450.2013.841547

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117201%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference