Taste receptors of the gut: emerging roles in health and disease (Q38153130)

29 August 2017

Taste receptors of the gut: emerging roles in health and disease (English)

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29 August 2017

Inge Depoortere

1

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PubMed ID

24131638

29 August 2017

language of work or name

English

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publication date

16 October 2013

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29 August 2017

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29 August 2017

63

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29 August 2017

179-190

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29 August 2017

1

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Taste buds as peripheral chemosensory processors

29 August 2017

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Mammalian sweet taste receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

An amino-acid taste receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

The receptors for mammalian sweet and umami taste

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Extraoral bitter taste receptors as mediators of off-target drug effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

T2Rs function as bitter taste receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

The Molecular Receptive Ranges of Human TAS2R Bitter Taste Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Bitter taste receptors and human bitter taste perception

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Taste receptors for umami: the case for multiple receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Functional expression of the extracellular-Ca2+-sensing receptor in mouse taste cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Nutrient sensing in the gut: new roads to therapeutics?

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Taste Preference for Fatty Acids Is Mediated by GPR40 and GPR120

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

The receptors and cells for mammalian taste

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Peptide regulators of peripheral taste function

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Gustatory stimuli representing different perceptual qualities elicit distinct patterns of neuropeptide secretion from taste buds

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Leptin as a modulator of sweet taste sensitivities in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Review article: the role of gastric motility in the control of food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Acyl and total ghrelin are suppressed strongly by ingested proteins, weakly by lipids, and biphasically by carbohydrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Bitter taste receptors and α-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Sensing of fatty acids for octanoylation of ghrelin involves a gustatory G-protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

T1R3 is expressed in brush cells and ghrelin-producing cells of murine stomach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Gustatory sensory cells express a receptor responsive to protein breakdown products (GPR92)

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Receptors responsive to protein breakdown products in g-cells and d-cells of mouse, swine and human

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Nutrient sensing receptors in gastric endocrine cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Calcium-sensing receptor is a physiologic multimodal chemosensor regulating gastric G-cell growth and gastrin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Effect of intravenous amino acids on interdigestive antroduodenal motility and small bowel transit time

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Expression and regulation of cholecystokinin and cholecystokinin receptors in rat nodose and dorsal root ganglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Glucagon-like peptide-1 inhibits voltage-gated potassium currents in mouse nodose ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

A recombinant human glucagon-like peptide (GLP)-1-albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Bilateral midbrain transections block the behavioral effects of cholecystokinin on feeding and exploration in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Free fatty acids induce cholecystokinin secretion through GPR120.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

TRPM5 is critical for linoleic acid-induced CCK secretion from the enteroendocrine cell line, STC-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

The G-protein-coupled receptor GPR40 directly mediates long-chain fatty acid-induced secretion of cholecystokinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Sensing of amino acids by the gut-expressed taste receptor T1R1-T1R3 stimulates CCK secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Calcium-sensing receptor mediates phenylalanine-induced cholecystokinin secretion in enteroendocrine STC-1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

The extracellular calcium-sensing receptor is required for cholecystokinin secretion in response to L-phenylalanine in acutely isolated intestinal I cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Amino acids stimulate cholecystokinin release through the Ca2+-sensing receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

GPR93 activation by protein hydrolysate induces CCK transcription and secretion in STC-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Bitter stimuli induce Ca2+ signaling and CCK release in enteroendocrine STC-1 cells: role of L-type voltage-sensitive Ca2+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Transformation of postingestive glucose responses after deletion of sweet taste receptor subunits or gastric bypass surgery

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Glucose-sensing in glucagon-like peptide-1-secreting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Glucose sensing in L cells: a primary cell study

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Bitter taste receptors influence glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

The G protein-coupled receptor family C group 6 subtype A (GPRC6A) receptor is involved in amino acid-induced glucagon-like peptide-1 secretion from GLUTag cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Expression of the short-chain fatty acid receptor, GPR43, in the human colon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Expression of short-chain fatty acid receptor GPR41 in the human colon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Gustducin couples fatty acid receptors to GLP-1 release in colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Disordered control of intestinal sweet taste receptor expression and glucose absorption in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Effects of oral ingestion of sucralose on gut hormone response and appetite in healthy normal-weight subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Effects of carbohydrate sugars and artificial sweeteners on appetite and the secretion of gastrointestinal satiety peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Metabolic surgery to treat type 2 diabetes: clinical outcomes and mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Duodenal-jejunal bypass improves glycemia and decreases SGLT1-mediated glucose absorption in rats with streptozotocin-induced type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Reduction of intestinal electrogenic glucose absorption after duodenojejunal bypass in a mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Effects of LX4211, a dual SGLT1/SGLT2 inhibitor, plus sitagliptin on postprandial active GLP-1 and glycemic control in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1 (SGLT1)-mediated absorption of intestinal glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Bariatric surgery and taste: novel mechanisms of weight loss.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Modulation of taste sensitivity by GLP-1 signaling in taste buds

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Perceived food intolerance in subjects with irritable bowel syndrome-- etiology, prevalence and consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Fructose malabsorption and symptoms of irritable bowel syndrome: guidelines for effective dietary management

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Dietary triggers of abdominal symptoms in patients with irritable bowel syndrome: randomized placebo-controlled evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Manipulation of dietary short chain carbohydrates alters the pattern of gas production and genesis of symptoms in irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Luminal propionate-induced secretory response in the rat distal colon in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Effects of short-chain fatty acids on gastrointestinal motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Short-chain fatty acids stimulate colonic transit via intraluminal 5-HT release in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Duodenal enteroendocrine I-cells contain mRNA transcripts encoding key endocannabinoid and fatty acid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Neural and non-neural mediation of propionate-induced contractile responses in the rat distal colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Efficacy of 5-HT3 antagonists and 5-HT4 agonists in irritable bowel syndrome: systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Proximal and distal gut hormone secretion in irritable bowel syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Eradication of small intestinal bacterial overgrowth reduces symptoms of irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

The small intestinal bacterial overgrowth. Irritable bowel syndrome hypothesis: implications for treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Small intestinal bacterial overgrowth in patients with irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Dysmotility of the small intestine in irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

GPR43/FFA2: physiopathological relevance and therapeutic prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Slc2a5 (Glut5) is essential for the absorption of fructose in the intestine and generation of fructose-induced hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Gluten causes gastrointestinal symptoms in subjects without celiac disease: a double-blind randomized placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

No effects of gluten in patients with self-reported non-celiac gluten sensitivity after dietary reduction of fermentable, poorly absorbed, short-chain carbohydrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

A controlled trial of gluten-free diet in patients with irritable bowel syndrome-diarrhea: effects on bowel frequency and intestinal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Intragastric monosodium L-glutamate stimulates motility of upper gut via vagus nerve in conscious dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Luminal amino acid sensing in the rat gastric mucosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Brain activation by umami substances via gustatory and visceral signaling pathways, and physiological significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Metabotropic glutamate receptors inhibit mechanosensitivity in vagal sensory neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Functional dyspepsia is associated with a greater symptomatic response to fat but not carbohydrate, increased fasting and postprandial CCK, and diminished PYY.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Cholecystokinin hyperresponsiveness in functional dyspepsia

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Artificial sweeteners: a place in the field of functional foods? Focus on obesity and related metabolic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

PYY modulation of cortical and hypothalamic brain areas predicts feeding behaviour in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

The functional involvement of gut-expressed sweet taste receptors in glucose-stimulated secretion of glucagon-like peptide-1 (GLP-1) and peptide YY (PYY)

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Intestinal serotonin release, sensory neuron activation, and abdominal pain in irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

Satiety role of the small intestine examined in sham-feeding rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2013-305112

10.1136/GUTJNL-2013-305112

21 January 2018

Identifiers

DOI

1 reference

29 August 2017

1 reference

PubMed ID

24131638