The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression (Q38161942)

30 August 2017

title

The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression (English)

1 reference

30 August 2017

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24219278%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Michael J. Hendzel

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24219278%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Leah C Young

series ordinal

1

1 reference

30 August 2017

Michael J Hendzel

series ordinal

2

1 reference

30 August 2017

publication date

5 December 2012

1 reference

Biochemistry and Cell Biology

30 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24219278%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

91

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24219278%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24219278%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

369-377

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24219278%20AND%20SRC:MED&resulttype=core&format=json

Histone methyltransferases in cancer

6 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Mutant genetic background affects the functional rearrangement and kinetic properties of JMJD2b histone demethylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Conserved antagonism between JMJD2A/KDM4A and HP1γ during cell cycle progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Characterization of a core fragment of the rhesus monkey TRIM5α protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Structural insights into histone demethylation by JMJD2 family members.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Structural basis of the recognition of a methylated histone tail by JMJD2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Linking Heterochromatin Protein 1 (HP1) to cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Nucleosomes in the neighborhood: new roles for chromatin modifications in replication origin control

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Histone methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Structural biology of the chromodomain: form and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Prognostic relevance of global histone H3 lysine 4 (H3K4) methylation in renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Global levels of histone modifications predict prostate cancer recurrence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Global histone modifications in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Chemical biology of lysine demethylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

G2 histone methylation is required for the proper segregation of chromosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

p53 is regulated by the lysine demethylase LSD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Jmjd2c histone demethylase enhances the expression of Mdm2 oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

The testis-enriched histone demethylase, KDM4D, regulates methylation of histone H3 lysine 9 during spermatogenesis in the mouse but is dispensable for fertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Tudor, MBT and chromo domains gauge the degree of lysine methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Effects of RNA interference-mediated gene silencing of JMJD2A on human breast cancer cell line MDA-MB-231 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Histone demethylase JMJD2B is required for tumor cell proliferation and survival and is overexpressed in gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

An epigenetic role for PRL-3 as a regulator of H3K9 methylation in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Characterization of Drosophila melanogaster JmjC+N histone demethylases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

The histone demethylase Dmel\Kdm4A controls genes required for life span and male-specific sex determination in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

IDH mutation impairs histone demethylation and results in a block to cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Cellular histone modification patterns predict prognosis and treatment response in resectable pancreatic adenocarcinoma: results from RTOG 9704.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Temporal expression of factors involved in chromatin remodeling and in gene regulation during early bovine in vitro embryo development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Dynamic changes in histone H3 lysine 9 methylations: identification of a mitosis-specific function for dynamic methylation in chromosome congression and segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

PHD fingers: epigenetic effectors and potential drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Handpicking epigenetic marks with PHD fingers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Adaptation of Hansenula polymorpha to methanol: a transcriptome analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Molecular recognition of H3/H4 histone tails by the tudor domains of JMJD2A: a comparative molecular dynamics simulations study

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Drosophila p53 Is Required to Increase the Levels of the dKDM4B Demethylase after UV-induced DNA Damage to Demethylate Histone H3 Lysine 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Heterochromatic genome stability requires regulators of histone H3 K9 methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Partitioning and plasticity of repressive histone methylation states in mammalian chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Identification of non-histone substrates for JMJD2A-C histone demethylases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

An infrequent case of neoplasm with fibroepithelioma of pinkus and hidradenomatous features arising at the umbilicus: a rare finding

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Cooperative epigenetic modulation by cancer amplicon genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Heterochromatin protein 1 (HP1) modulates replication timing of the Drosophila genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Cancer-associated alteration of pericentromeric heterochromatin may contribute to chromosome instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Histone Demethylase JmjD2A Regulates Neural Crest Specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Hypoxia causes epigenetic gene regulation in macrophages by attenuating Jumonji histone demethylase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Histone demethylation by a family of JmjC domain-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Understanding the language of Lys36 methylation at histone H3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

The histone demethylase JMJD2C is stage-specifically expressed in preimplantation mouse embryos and is required for embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Loss of trimethylation at lysine 27 of histone H3 is a predictor of poor outcome in breast, ovarian, and pancreatic cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Targeting hypoxia in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

SWI/SNF nucleosome remodellers and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Dynamic nuclear organization of constitutive heterochromatin during fetal male germ cell development in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FBCB-2012-0054

21 January 2018

Identifiers

DOI

10.1139/BCB-2012-0054

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24219278%20AND%20SRC:MED&resulttype=core&format=json

release_ctdpnzjl3naszi5cdn2ebuijce

6 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ctdpnzjl3naszi5cdn2ebuijce

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference