The importance of autophagy in cardioprotection (Q38162827)

30 August 2017

title

The importance of autophagy in cardioprotection (English)

1 reference

30 August 2017

0 references

Sebastiano Sciarretta

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24235024%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Junichi Sadoshima

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24235024%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Derek Yee

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24235024%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Varun Shenoy

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24235024%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Narayani Nagarajan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24235024%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

publication date

14 November 2013

1 reference

High Blood Pressure & Cardiovascular Prevention

30 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24235024%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24235024%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24235024%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

21-28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24235024%20AND%20SRC:MED&resulttype=core&format=json

Autophagy, myocardial protection, and the metabolic syndrome.

7 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Is autophagy in response to ischemia and reperfusion protective or detrimental for the heart?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Pharmacological modulation of autophagy during cardiac stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Rheb is a critical regulator of autophagy during myocardial ischemia: pathophysiological implications in obesity and metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Is reactivation of autophagy a possible therapeutic solution for obesity and metabolic syndrome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Autophagy in immunity and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Autophagy in the Pathogenesis of Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Regulation mechanisms and signaling pathways of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Activation of NADPH oxidase 4 in the endoplasmic reticulum promotes cardiomyocyte autophagy and survival during energy stress through the protein kinase RNA-activated-like endoplasmic reticulum kinase/eukaryotic initiation factor 2α/activating trans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Disease model: LAMP-2 enlightens Danon disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Autophagy during cardiac stress: joys and frustrations of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Cardiac autophagy is a maladaptive response to hemodynamic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Autophagy in chronically ischemic myocardium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Differential roles of GSK-3β during myocardial ischemia and ischemia/reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Autophagy fights disease through cellular self-digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Autophagy: from phenomenology to molecular understanding in less than a decade

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Selective degradation of mitochondria by mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Mitochondrial degradation by autophagy (mitophagy) in GFP-LC3 transgenic hepatocytes during nutrient deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Molecular mechanisms and physiological significance of autophagy during myocardial ischemia and reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

The TSC/Rheb/TOR signaling pathway in fission yeast and mammalian cells: temperature sensitive and constitutive active mutants of TOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

AMPK phosphorylation of raptor mediates a metabolic checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

mTOR regulates autophagy-associated genes downstream of p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

TFEB links autophagy to lysosomal biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

The Rheb family of GTP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Microtubule-associated protein/microtubule affinity-regulating kinase 4 (MARK4) is a negative regulator of the mammalian target of rapamycin complex 1 (mTORC1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Genetic and pharmacological inhibition of Rheb1-mTORC1 signaling exerts cardioprotection against adverse cardiac remodeling in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Rheb (Ras homologue enriched in brain)-dependent mammalian target of rapamycin complex 1 (mTORC1) activation becomes indispensable for cardiac hypertrophic growth after early postnatal period

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Metabolic syndrome in patients with acute myocardial infarction is associated with increased infarct size and in-hospital complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Prevalence and impact of metabolic syndrome on hospital outcomes in acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

mTOR signalling: the molecular interface connecting metabolic stress, aging and cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Comparison of the effect of the metabolic syndrome and multiple traditional cardiovascular risk factors on vascular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Downregulation of the longevity-associated protein sirtuin 1 in insulin resistance and metabolic syndrome: potential biochemical mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Regulation and role of autophagy in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Akt2 knockout preserves cardiac function in high-fat diet-induced obesity by rescuing cardiac autophagosome maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Regulation of lipid stores and metabolism by lipophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic β-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Autophagy as a therapeutic target in diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Autophagy in atherosclerosis: a potential drug target for plaque stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Chemical modulators of autophagy as biological probes and potential therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Carbon monoxide activates autophagy via mitochondrial reactive oxygen species formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Association of left ventricular hypertrophy with metabolic risk factors: the HyperGEN study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Obesity and the risk of heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40292-013-0029-9

Interaction of Insulin and AMPK in the Ischemic Heart

21 January 2018

1 reference

12 December 2020

The metabolic syndrome

1 reference

12 December 2020

Impact of obesity as a mortality predictor in high-risk patients with myocardial infarction or chronic heart failure: a pooled analysis of five registries

1 reference

12 December 2020

AMPK mediates autophagy during myocardial ischemia in vivo

1 reference

12 December 2020

Inhibition of autophagy in the heart induces age-related cardiomyopathy

1 reference

12 December 2020

10.1007/S40292-013-0029-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24235024%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference