Secreted heat shock protein gp96-Ig: next-generation vaccines for cancer and infectious diseases (Q38164258)

30 August 2017

Secreted heat shock protein gp96-Ig: next-generation vaccines for cancer and infectious diseases (English)

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30 August 2017

Natasa Strbo

1

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30 August 2017

Arlene Garcia-Soto

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2

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30 August 2017

Taylor H Schreiber

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3

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30 August 2017

Eckhard R Podack

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4

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30 August 2017

1 December 2013

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30 August 2017

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30 August 2017

57

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30 August 2017

1-3

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30 August 2017

311-325

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https://scigraph.springernature.com/pub.10.1007/s12026-013-8468-x

30 August 2017

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21 January 2018

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Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability

21 January 2018

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Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway

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21 January 2018

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The receptor for heat shock protein 60 on macrophages is saturable, specific, and distinct from receptors for other heat shock proteins

21 January 2018

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CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin

21 January 2018

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Essential role of CD91 in re-presentation of gp96-chaperoned peptides

21 January 2018

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SREC-I, a type F scavenger receptor, is an endocytic receptor for calreticulin.

21 January 2018

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21 January 2018

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21 January 2018

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Dendritic cells sequester antigenic epitopes for prolonged periods in the absence of antigen-encoding genetic information

21 January 2018

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Heat shock proteins gp96 and hsp70 activate the release of nitric oxide by APCs

21 January 2018

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Cutting edge: heat shock protein gp96 induces maturation and migration of CD11c+ cells in vivo

21 January 2018

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Gp96 SIV Ig immunization induces potent polyepitope specific, multifunctional memory responses in rectal and vaginal mucosa

21 January 2018

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Cutting edge: novel vaccination modality provides significant protection against mucosal infection by highly pathogenic simian immunodeficiency virus

21 January 2018

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Molecular and cellular requirements for enhanced antigen cross-presentation to CD8 cytotoxic T lymphocytes.

21 January 2018

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Secreted heat shock protein gp96-Ig: an innovative vaccine approach

21 January 2018

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21 January 2018

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Perforin is required for innate and adaptive immunity induced by heat shock protein gp96.

21 January 2018

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21 January 2018

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The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response

21 January 2018

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The precursors of memory: models and controversies.

21 January 2018

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Development, trafficking, and function of memory T-cell subsets

21 January 2018

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IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates

21 January 2018

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Cell-secreted Gp96-Ig-peptide complexes induce lamina propria and intraepithelial CD8+ cytotoxic T lymphocytes in the intestinal mucosa.

21 January 2018

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21 January 2018

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21 January 2018

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Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing

21 January 2018

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Regulatory T cells and intestinal homeostasis

21 January 2018

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Tumor-driven evolution of immunosuppressive networks during malignant progression

21 January 2018

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Cancer immunoediting: from immunosurveillance to tumor escape

21 January 2018

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2011: the immune hallmarks of cancer

21 January 2018

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Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

PI(3) kinase is associated with a mechanism of immunoresistance in breast and prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Tumor-induced suppression of CTL expansion and subjugation by gp96-Ig vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Tumor antigen specific iTreg accumulate in the tumor microenvironment and suppress therapeutic vaccination

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Tumor immunogenicity and responsiveness to cancer vaccine therapy: the state of the art

21 January 2018

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

21 January 2018

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Insight into the heterogeneity of breast cancer through next-generation sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Heat shock proteins transfer peptides during antigen processing and CTL priming

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Anticancer drugs cause release of exosomes with heat shock proteins from human hepatocellular carcinoma cells that elicit effective natural killer cell antitumor responses in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Heat-shock induction of tumor-derived danger signals mediates rapid monocyte differentiation into clinically effective dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Generation of murine CTL by a hepatitis B virus-specific peptide and evaluation of the adjuvant effect of heat shock protein glycoprotein 96 and its terminal fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

DNA vaccination with gp96-peptide fusion proteins induces protection against an intracellular bacterial pathogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Glycoprotein 96 can chaperone both MHC class I- and class II-restricted epitopes for in vivo presentation, but selectively primes CD8+ T cell effector function

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Different domains of glycoprotein 96 influence HPV16 E7 DNA vaccine potency via electroporation mediated delivery in tumor mice model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

The contribution of NT-gp96 as an adjuvant for increasing HPV16 E7-specific immunity in C57BL /6 mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Comparison of adjuvant activity of N- and C-terminal domain of gp96 in a Her2-positive breast cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

GP96 C-terminal improves Her2/neu DNA vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Immunization of cancer patients with autologous cancer-derived heat shock protein gp96 preparations: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Human tumor-derived heat shock protein 96 mediates in vitro activation and in vivo expansion of melanoma- and colon carcinoma-specific T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Autologous tumor-derived heat-shock protein peptide complex-96 (HSPPC-96) in patients with metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Experience with heat shock protein-peptide complex 96 vaccine therapy in patients with indolent non-Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

A phase I pilot study of autologous heat shock protein vaccine HSPPC-96 in patients with resected pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: the C-100-21 Study Group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Vaccination of metastatic renal cell carcinoma patients with autologous tumour-derived vitespen vaccine: clinical findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Individual patient-specific immunity against high-grade glioma after vaccination with autologous tumor derived peptides bound to the 96 KD chaperone protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Genes coding for melanoma antigens recognised by cytolytic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Identification of a new shared HLA-A2.1 restricted epitope from the melanoma antigen tyrosinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Gene expression profiling of non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Increased prevalence of regulatory T cells (Treg) is induced by pancreas adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Regulatory T cells in cancer

21 January 2018

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Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses

21 January 2018

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Protective attenuated lentivirus immunization induces SIV-specific T cells in the genital tract of rhesus monkeys.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

With minimal systemic T-cell expansion, CD8+ T Cells mediate protection of rhesus macaques immunized with attenuated simian-human immunodeficiency virus SHIV89.6 from vaginal challenge with simian immunodeficiency virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Glycoprotein 96-activated dendritic cells induce a CD8-biased T cell response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

T cell costimulation by TNFR superfamily (TNFRSF)4 and TNFRSF25 in the context of vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Dendritic Cell-Induced Memory T Cell Activation in Nonlymphoid Tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Vaccination of Metastatic Melanoma Patients With Autologous Tumor-Derived Heat Shock Protein gp96-Peptide Complexes: Clinical and Immunologic Findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

A phase II trial of vaccination with autologous, tumor-derived heat-shock protein peptide complexes Gp96, in combination with GM-CSF and interferon-α in metastatic melanoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-013-8468-X

A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides

21 January 2018

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12 December 2020

How cells respond to stress

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12 December 2020

The challenges of bringing autologous HSP-based vaccines to commercial reality

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12 December 2020

CD91: a receptor for heat shock protein gp96

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12 December 2020

Heat shock proteins, autoimmunity, and cancer treatment

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12 December 2020

High efficiency CD91- and LOX-1-mediated re-presentation of gp96-chaperoned peptides by MHC II molecules

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12 December 2020

Methods of purification of heat shock protein-peptide complexes for use as vaccines against cancers and infectious diseases

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12 December 2020

Vaccination with autologous tumor-derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer

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12 December 2020

Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations

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12 December 2020

Structure and assembly of the endoplasmic reticulum. Biosynthetic sorting of endoplasmic reticulum proteins

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12 December 2020

Cutting edge: receptor-mediated endocytosis of heat shock proteins by professional antigen-presenting cells.

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12 December 2020

Determinants of efficacy of immunotherapy with tumor-derived heat shock protein gp96

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12 December 2020

Evidence that glycoprotein 96 (B2), a stress protein, functions as a Th2-specific costimulatory molecule

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12 December 2020

Tumor rejection antigen gp96/grp94 is an ATPase: implications for protein folding and antigen presentation

1 reference

12 December 2020

The N-terminal fragment of GRP94 is sufficient for peptide presentation via professional antigen-presenting cells

1 reference

12 December 2020

Phylogenetic Conservation of Glycoprotein 96 Ability to Interact with CD91 and Facilitate Antigen Cross-Presentation

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12 December 2020

Purification of immunogenic heat shock protein 70-peptide complexes by ADP-affinity chromatography

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12 December 2020

Comparison of tumor-specific immunogenicities of stress-induced proteins gp96, hsp90, and hsp70

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12 December 2020

Minor H antigens introduced on H-2 different stimulating cells cross-react at the cytotoxic T cell level during in vivo priming

1 reference

12 December 2020

Heat shock proteins generate beta-chemokines which function as innate adjuvants enhancing adaptive immunity

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12 December 2020

Heat shock and development. Introduction

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12 December 2020

Endoplasmic reticulum contains a common, abundant calcium-binding glycoprotein, endoplasmin

1 reference

12 December 2020

Enhancing the potency of HBV DNA vaccines using fusion genes of HBV-specific antigens and the N-terminal fragment of gp96

1 reference

12 December 2020

Interaction of Endoplasmic Reticulum Chaperone GRP94 with Peptide Substrates Is Adenine Nucleotide-independent

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12 December 2020

Heat shock proteins refine the danger theory

1 reference

12 December 2020

Expression of a shared tumor-specific antigen by two chemically induced BALB/c sarcomas.

1 reference

12 December 2020

Human 60-kDa heat-shock protein: a danger signal to the innate immune system

1 reference

12 December 2020

Cutting edge: tumor secreted heat shock-fusion protein elicits CD8 cells for rejection.

1 reference

12 December 2020

Saturation, competition, and specificity in interaction of heat shock proteins (hsp) gp96, hsp90, and hsp70 with CD11b+ cells

1 reference

12 December 2020

Isolation of MHC class I-restricted tumor antigen peptide and its precursors associated with heat shock proteins hsp70, hsp90, and gp96

1 reference

12 December 2020

Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma

1 reference

12 December 2020

A phase II study of heat shock protein-peptide complex-96 vaccine therapy in patients with indolent non-Hodgkin's lymphoma

1 reference

12 December 2020

HSP70 and HSP90 Differentially Regulate Translocation of Extracellular Antigen to the Cytosol for Cross-Presentation

1 reference

12 December 2020

The heat shock protein gp96 induces maturation of dendritic cells and down-regulation of its receptor

1 reference

12 December 2020

10.1007/S12026-013-8468-X

Identifiers

DOI

1 reference

Dimensions Publication ID

30 August 2017

0 references

1 reference