Mismatch repair deficiency in ovarian cancer -- molecular characteristics and clinical implications (Q38170877)

30 August 2017

Mismatch repair deficiency in ovarian cancer -- molecular characteristics and clinical implications (English)

1 reference

30 August 2017

1 reference

1 reference

Xue Xiao

1

1 reference

30 August 2017

David W Melton

series ordinal

2

1 reference

30 August 2017

Charlie Gourley

series ordinal

3

1 reference

30 August 2017

language of work or name

English

0 references

publication date

10 December 2013

1 reference

30 August 2017

1 reference

30 August 2017

132

1 reference

30 August 2017

506-512

1 reference

30 August 2017

2

1 reference

Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling

30 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Newly diagnosed and relapsed epithelial ovarian carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Differences in tumor type in low-stage versus high-stage ovarian carcinomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Histologic, molecular, and cytogenetic features of ovarian cancers: implications for diagnosis and treatment.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

The histologic type and stage distribution of ovarian carcinomas of surface epithelial origin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Population BRCA1 and BRCA2 mutation frequencies and cancer penetrances: a kin-cohort study in Ontario, Canada

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Germline BRCA1 and BRCA2 Mutations in Ovarian Cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

The contribution of the hereditary nonpolyposis colorectal cancer syndrome to the development of ovarian cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

BRCA1, BRCA2, and hereditary nonpolyposis colorectal cancer gene mutations in an unselected ovarian cancer population: relationship to family history and implications for genetic testing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Mechanisms and functions of DNA mismatch repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

8-oxoguanine incorporation into DNA repeats in vitro and mismatch recognition by MutSalpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

A review of the clinical relevance of mismatch-repair deficiency in ovarian cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Mechanisms in eukaryotic mismatch repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Endonucleolytic function of MutLalpha in human mismatch repair.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

DNA mismatch repair: molecular mechanism, cancer, and ageing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

The role of the human DNA mismatch repair gene hMSH2 in DNA repair, cell cycle control and apoptosis: implications for pathogenesis, progression and therapy of cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

The genetics of HNPCC: application to diagnosis and screening

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Microsatellite instability of selective target genes in HNPCC-associated colon adenomas.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Mutation and cancer: statistical study of retinoblastoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Microsatellite instability, MLH-1 promoter hypermethylation, and frameshift mutations at coding mononucleotide repeat microsatellites in ovarian tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

DNA methylation: an alternative pathway to cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Life-time risk of different cancers in hereditary non-polyposis colorectal cancer (HNPCC) syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Hereditary ovarian carcinoma: heterogeneity, molecular genetics, pathology, and management

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Ovarian cancer at young age: the contribution of mismatch-repair defects in a population-based series of epithelial ovarian cancer before age 40

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Microsatellite instability and alteration of the expression of hMLH1 and hMSH2 in ovarian clear cell carcinoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Molecular genetic alterations in endometrioid carcinomas of the ovary: similar frequency of beta-catenin abnormalities but lower rate of microsatellite instability and PTEN alterations than in uterine endometrioid carcinomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Microsatellite instability and mismatch repair protein defects in ovarian epithelial neoplasms in patients 50 years of age and younger.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

A change in microsatellite instability caused by cisplatin-based chemotherapy of ovarian cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Immunohistochemical staining of hMLH1 and hMSH2 reflects microsatellite instability status in ovarian carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Mismatch repair gene expression defects contribute to microsatellite instability in ovarian carcinoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Mismatch repair and treatment resistance in ovarian cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Systematic review of microsatellite instability and colorectal cancer prognosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Carcinogenesis. Missing mismatch repair.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Survival of Patients with Ovarian Cancer due to a Mismatch Repair Defect

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Loss of hMLH1 expression correlates with improved survival in stage III-IV ovarian cancer patients.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Survival in women with MMR mutations and ovarian cancer: a multicentre study in Lynch syndrome kindreds.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Candidate DNA methylation drivers of acquired cisplatin resistance in ovarian cancer identified by methylome and expression profiling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

hMSH2 and GTBP expression in advanced stage epithelial ovarian cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Chemotherapy resistant ovarian cancer in carriers of an hMSH2 mutation?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Parallel high-throughput RNA interference screens identify PINK1 as a potential therapeutic target for the treatment of DNA mismatch repair-deficient cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

DNA polymerases as potential therapeutic targets for cancers deficient in the DNA mismatch repair proteins MSH2 or MLH1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Ovarian endometrioid adenocarcinoma: incidence and clinical significance of the morphologic and immunohistochemical markers of mismatch repair protein defects and tumor microsatellite instability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Primary ovarian carcinomas display multiple methylator phenotypes involving known tumor suppressor genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

Alternate molecular genetic pathways in ovarian carcinomas of common histological types.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.12.003

10.1016/J.YGYNO.2013.12.003

7 January 2021

Identifiers

DOI

1 reference

30 August 2017

1 reference