Lung cancer stem cells and implications for future therapeutics (Q38189297)

30 August 2017

Lung cancer stem cells and implications for future therapeutics (English)

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30 August 2017

neoplastic stem cells

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Jing Wang

1

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30 August 2017

Ze-hong Li

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2

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30 August 2017

James White

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3

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30 August 2017

Lin-bo Zhang

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4

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30 August 2017

1 July 2014

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Cell Biochemistry and Biophysics

30 August 2017

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30 August 2017

69

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30 August 2017

3

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30 August 2017

389-398

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https://scigraph.springernature.com/pub.10.1007/s12013-014-9844-4

30 August 2017

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Global burden of cancers attributable to infections in 2008: a review and synthetic analysis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Third CECOG consensus on the systemic treatment of non-small-cell lung cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Metastatic non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Non-small-cell lung cancer.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Cancer stem cells: in the line of fire

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Selective targeting of cancer stem cells: a new concept in cancer therapeutics

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

A role for cancer stem cells in drug resistance and metastasis in non-small-cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Local recurrence after surgery for early stage lung cancer: an 11-year experience with 975 patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Stage of lung cancer in relation to its size: part 2. Evidence

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Mechanisms of acquired crizotinib resistance in ALK-rearranged lung Cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Twenty-five years of clinical research for patients with limited-stage small cell lung carcinoma in North America

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Lung cancer stem cell: new insights on experimental models and preclinical data.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Cancer stem cells: current status and evolving complexities

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Cancer stem cells in solid tumors: elusive or illusive?

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Prospective identification of tumorigenic breast cancer cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Cancer stem cells: a new framework for the design of tumor therapies.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Lung cancer stem cells: progress and prospects

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Mechanisms of stem cell self-renewal

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Identification and expansion of the tumorigenic lung cancer stem cell population

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Both CD133+ and CD133- subpopulations of A549 and H446 cells contain cancer-initiating cells.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Molecular characterisation of side population cells with cancer stem cell-like characteristics in small-cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Identification of uPAR-positive chemoresistant cells in small cell lung cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Non-small cell lung cancer stem/progenitor cells are enriched in multiple distinct phenotypic subpopulations and exhibit plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Low molecular weight heparin ablates lung cancer cisplatin-resistance by inducing proteasome-mediated ABCG2 protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

The side population in human lung cancer cell line NCI-H460 is enriched in stem-like cancer cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Aldehyde dehydrogenase-1 is a specific marker for stem cells in human lung adenocarcinoma.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Subpopulation of small-cell lung cancer cells expressing CD133 and CD87 show resistance to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: implications for the emergence and reversal of cancer drug resistance

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Characterization of a stem cell population in lung cancer A549 cells.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Side population rather than CD133(+) cells distinguishes enriched tumorigenicity in hTERT-immortalized primary prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Significance of CD44 and CD24 as cancer stem cell markers: an enduring ambiguity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Human ovarian cancer stem cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Inhibition of Functional Hyaluronan-CD44 Interactions in CD133-positive Primary Human Ovarian Carcinoma Cells by Small Hyaluronan Oligosaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Non-small cell lung cancer cells expressing CD44 are enriched for stem cell-like properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

ABCG2: the key to chemoresistance in cancer stem cells?

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Impact of breast cancer resistance protein on cancer treatment outcomes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Constitutive expression of the ATP-binding cassette transporter ABCG2 enhances the growth potential of early human hematopoietic progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Drug-selected human lung cancer stem cells: cytokine network, tumorigenic and metastatic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

CD133 positive endothelial progenitor cells contribute to the tumour vasculature in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

ALDH-positive lung cancer stem cells confer resistance to epidermal growth factor receptor tyrosine kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Developmental signaling pathways in cancer stem cells of solid tumors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Controversies in cancer stem cells: targeting embryonic signaling pathways

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Hedgehog: functions and mechanisms

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

A crucial requirement for Hedgehog signaling in small cell lung cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Notch in lung development and lung cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Constitutive activation of Notch3 inhibits terminal epithelial differentiation in lungs of transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Notch signaling contributes to lung cancer clonogenic capacity in vitro but may be circumvented in tumorigenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Alterations of the Notch pathway in lung cancer.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Notch1 functions as a tumor suppressor in mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Angiogenesis: a team effort coordinated by notch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Wnt signaling: is the party in the nucleus?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Wnt signaling in stem cells and non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Wnt/beta-catenin signaling regulates cancer stem cells in lung cancer A549 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell growth and overcomes drug resistance of lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Inhibition of telomerase activity preferentially targets aldehyde dehydrogenase-positive cancer stem-like cells in lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Effects of the Hedgehog pathway inhibitor GDC-0449 on lung cancer cell lines are mediated by side populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

The fuzzy math of solid tumor stem cells: a perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Efficient tumour formation by single human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Normal stem cells and cancer stem cells: the niche matters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

Cancer stem cells: mirage or reality?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

CD44 is of Functional Importance for Colorectal Cancer Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-014-9844-4

10.1007/S12013-014-9844-4

21 January 2018

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Dimensions Publication ID

30 August 2017

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