Familial Alzheimer's disease modelling using induced pluripotent stem cell technology (Q38207606)

31 August 2017

Familial Alzheimer's disease modelling using induced pluripotent stem cell technology (English)

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31 August 2017

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Lisa Mohamet

1

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31 August 2017

Natalie J Miazga

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2

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31 August 2017

Christopher M Ward

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3

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31 August 2017

1 April 2014

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World Journal of Stem Cells

31 August 2017

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31 August 2017

6

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2

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31 August 2017

239-247

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describes a project that uses

31 August 2017

induced pluripotent stem cell

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based on heuristic

inferred from title

cites work

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Down's syndrome, neuroinflammation, and Alzheimer neuropathogenesis

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6 September 2017

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6 September 2017

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The triggering receptor expressed on myeloid cells 2: "TREM-ming" the inflammatory component associated with Alzheimer's disease

6 September 2017

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AZD1080, a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans

6 September 2017

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Cerebrovascular effects of apolipoprotein E: implications for Alzheimer disease

6 September 2017

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6 September 2017

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Discovery of AZD3839, a Potent and Selective BACE1 Inhibitor Clinical Candidate for the Treatment of Alzheimer Disease

6 September 2017

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Induced pluripotent stem cells: the new patient?

6 September 2017

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Small-molecule structure correctors target abnormal protein structure and function: structure corrector rescue of apolipoprotein E4-associated neuropathology

6 September 2017

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A novel inhibitor of amyloid β (Aβ) peptide aggregation: from high throughput screening to efficacy in an animal model of Alzheimer disease

6 September 2017

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Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks

6 September 2017

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6 September 2017

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Apolipoprotein E genotype: the innocent bystander or active bridge between metabolic syndrome and cognitive impairment?

6 September 2017

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6 September 2017

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6 September 2017

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Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells

6 September 2017

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Identification of small molecule inhibitors of neurite loss induced by Aβ peptide using high content screening.

6 September 2017

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Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons

6 September 2017

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Constructing and deconstructing stem cell models of neurological disease

6 September 2017

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APP processing in Alzheimer's disease

6 September 2017

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Genetics of Alzheimer disease

6 September 2017

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Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease

6 September 2017

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High content screening: seeing is believing.

6 September 2017

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High-content screening of primary neurons: ready for prime time

6 September 2017

1 reference

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The amyloid hypothesis for Alzheimer's disease: a critical reappraisal

6 September 2017

1 reference

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High-content analysis in neuroscience

6 September 2017

1 reference

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

6 September 2017

1 reference

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A high-throughput screen for compounds that inhibit aggregation of the Alzheimer's peptide

6 September 2017

1 reference

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High-content screening moves to the front of the line

6 September 2017

1 reference

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Can the pharmaceutical industry reduce attrition rates?

6 September 2017

1 reference

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Synthetic small molecules that control stem cell fate

6 September 2017

1 reference

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The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function

6 September 2017

1 reference

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Stable mutated tau441 transfected SH-SY5Y cells as screening tool for Alzheimer's disease drug candidates

6 September 2017

1 reference

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A human stem cell model of early Alzheimer's disease pathology in Down syndrome

6 September 2017

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Neuronal models for evaluation of proliferation in vitro using high content screening

6 September 2017

1 reference

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Formation and propagation of tau oligomeric seeds

14 September 2017

1 reference

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Modeling familial Alzheimer's disease with induced pluripotent stem cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999781

Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999781

Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999781

Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999781

High content screen microscopy analysis of A beta 1-42-induced neurite outgrowth reduction in rat primary cortical neurons: neuroprotective effects of alpha 7 neuronal nicotinic acetylcholine receptor ligands.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999781

High throughput screens for the identification of compounds that alter the accumulation of the Alzheimer's amyloid beta peptide (Abeta).

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3999781

31 August 2018

Identifiers

DOI

10.4252/WJSC.V6.I2.239

1 reference

31 August 2017

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31 August 2017

PubMed publication ID

24772250

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