The role of micro-RNAs in hepatocellular carcinoma: from molecular biology to treatment. (Q38213933)

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19 March 2020

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14 November 2020

The role of micro-RNAs in hepatocellular carcinoma: from molecular biology to treatment (English)

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19 March 2020

main subject

hepatocellular carcinoma

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14 November 2020

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14 November 2020

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14 November 2020

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2

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19 March 2020

Mario Scartozzi

3

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19 March 2020

Maristella Bianconi

5

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19 March 2020

Stefano Cascinu

8

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19 March 2020

7

Nicola Silvestris

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19 March 2020

author name string

Marco D'Anzeo

1

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19 March 2020

Riccardo Giampieri

4

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19 March 2020

Michela Del Prete

6

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19 March 2020

language of work or name

English

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publication date

19 May 2014

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19 March 2020

14 November 2020

2 references

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19 March 2020

14 November 2020

19

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19 March 2020

issue

5

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19 March 2020

page(s)

6393-6406

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Creative Commons Attribution

19 March 2020

copyright license

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14 November 2020

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Global cancer statistics in the year 2000.

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https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Hepatocellular carcinoma: Epidemiology, risk factors and pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Strategies for the management of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Hepatectomy for hepatocellular carcinoma: patient selection and postoperative outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Origins and Mechanisms of miRNAs and siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Most mammalian mRNAs are conserved targets of microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Identification of metastasis-related microRNAs in hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNAs and cell cycle regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA control of lifespan and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNAs in vertebrate development

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

The Drosha-DGCR8 complex in primary microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

The role of microRNAs in liver cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

The microcosmos of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

The role of microRNAs in hepatocarcinogenesis: current knowledge and future prospects.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Role of microRNAs in hepatitis B virus replication and pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA-18a prevents estrogen receptor-alpha expression, promoting proliferation of hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Modulation of hepatitis B virus replication and hepatocyte differentiation by MicroRNA-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression in human hepatoma cells expressing hepatitis C viral proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA-217 promotes ethanol-induced fat accumulation in hepatocytes by down-regulating SIRT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Downregulation of miR-122 in the rodent and human hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Clinical significance and potential of hepatic microRNA-122 expression in hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

miR-122 targets an anti-apoptotic gene, Bcl-w, in human hepatocellular carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Elevated expression of the miR-17-92 polycistron and miR-21 in hepadnavirus-associated hepatocellular carcinoma contributes to the malignant phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA-21 acts as an oncomir through multiple targets in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Hepatitis C virus-induced up-regulation of microRNA-155 promotes hepatocarcinogenesis by activating Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Analysis of sequence variations in 59 microRNAs in hepatocellular carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Association of a variant in MIR 196A2 with susceptibility to hepatocellular carcinoma in male Chinese patients with chronic hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Interplay between microRNAs and the epigenetic machinery: an intricate network

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Epigenetic modification of MiR-429 promotes liver tumour-initiating cell properties by targeting Rb binding protein 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA-101 inhibits human hepatocellular carcinoma progression through EZH2 downregulation and increased cytostatic drug sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Promising Candidate Urinary MicroRNA Biomarkers for the Early Detection of Hepatocellular Carcinoma among High-Risk Hepatitis C Virus Egyptian Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Circulating microRNAs as stable blood-based markers for cancer detection

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBV-positive hepatocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Sequential alterations of microRNA expression in hepatocellular carcinoma development and venous metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA expression, survival, and response to interferon in liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Specificity, duplex degradation and subcellular localization of antagomirs

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

The Promise of MicroRNA Replacement Therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Modulation of the unfolded protein response is the core of microRNA-122-involved sensitivity to chemotherapy in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

MicroRNAs and other non-coding RNAs as targets for anticancer drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Current status of miRNA-targeting therapeutics and preclinical studies against gastroenterological carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES19056393

Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas

21 January 2018

1 reference

12 December 2020

MicroRNA-30d promotes tumor invasion and metastasis by targeting Galphai2 in hepatocellular carcinoma

1 reference

12 December 2020

Gain of miR-151 on chromosome 8q24.3 facilitates tumour cell migration and spreading through downregulating RhoGDIA

1 reference

12 December 2020

Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma

1 reference

12 December 2020

A functional polymorphism in pre-microRNA-196a-2 contributes to the susceptibility of hepatocellular carcinoma in a Turkish population: a case-control study

1 reference

12 December 2020

MicroRNA-122 sensitizes HCC cancer cells to adriamycin and vincristine through modulating expression of MDR and inducing cell cycle arrest.

1 reference

12 December 2020

Clinical significance and prognostic value of microRNA expression signatures in hepatocellular carcinoma

1 reference

12 December 2020

Identification of typical miRNAs and target genes in hepatocellular carcinoma by DNA microarray technique

1 reference

12 December 2020

Prospective study of alpha-fetoprotein in cirrhotic patients monitored for development of hepatocellular carcinoma

1 reference

12 December 2020

10.3390/MOLECULES19056393

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24853455%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24853455%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

PubMed publication ID

24853455

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24853455%20AND%20SRC:MED&resulttype=core&format=json