The TRPC family of TRP channels: roles inferred (mostly) from knockout mice and relationship to ORAI proteins (Q38222953)

31 August 2017

The TRPC family of TRP channels: roles inferred (mostly) from knockout mice and relationship to ORAI proteins (English)

1 reference

31 August 2017

0 references

3

Lutz Birnbaumer

1 reference

31 August 2017

Yanhong Liao

1

1 reference

PubMed ID

24961980

31 August 2017

Joel Abramowitz

series ordinal

2

1 reference

PubMed ID

24961980

31 August 2017

language of work or name

1 reference

1 January 2014

1 reference

Handbook of experimental pharmacology

31 August 2017

1 reference

31 August 2017

223

1 reference

31 August 2017

1055-1075

1 reference

Ca2+ entry via TRPC channels is necessary for thrombin-induced NF-kappaB activation in endothelial cells through AMP-activated protein kinase and protein kinase Cdelta

31 August 2017

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Conserved gating elements in TRPC4 and TRPC5 channels

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Elucidation of a TRPC6-TRPC5 channel cascade that restricts endothelial cell movement

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Functional requirement for Orai1 in store-operated TRPC1-STIM1 channels

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Increased vascular smooth muscle contractility in TRPC6-/- mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Pressure-induced and store-operated cation influx in vascular smooth muscle cells is independent of TRPC1

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

TRPC6 enhances angiotensin II-induced albuminuria

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Ca2+ release-activated Ca2+ channel blockade as a potential tool in antipancreatitis therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Hair loss and defective T- and B-cell function in mice lacking ORAI1

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Transient receptor potential channels function as a coincidence signal detector mediating phosphatidylserine exposure.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

TRPC3 channels are required for synaptic transmission and motor coordination

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Crystal Structure of the Calcium Release-Activated Calcium Channel Orai

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

ORAI1 deficiency impairs activated T cell death and enhances T cell survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Orai proteins interact with TRPC channels and confer responsiveness to store depletion.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

A role for Orai in TRPC-mediated Ca2+ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca2+ entry.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Relaxed selective pressure on an essential component of pheromone transduction in primate evolution

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Orai1 subunit stoichiometry of the mammalian CRAC channel pore.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

The TRPC3 channel has a large internal chamber surrounded by signal sensing antennas

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Contribution of transient receptor potential channels to the control of GABA release from dendrites

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Amplification of CRAC current by STIM1 and CRACM1 (Orai1)

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Intrinsic phototransduction persists in melanopsin-expressing ganglion cells lacking diacylglycerol-sensitive TRPC subunits

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

PKC-dependent coupling of calcium permeation through transient receptor potential canonical 3 (TRPC3) to calcineurin signaling in HL-1 myocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Diverse properties of store-operated TRPC channels activated by protein kinase C in vascular myocytes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Involvement of myoendothelial gap junctions in the actions of endothelium-derived hyperpolarizing factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Transient receptor potential canonical type 3 channels facilitate endothelium-derived hyperpolarization-mediated resistance artery vasodilator activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

TRPC1 channels are critical for hypertrophic signaling in the heart

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

TRPC6 channels stimulated by angiotensin II are inhibited by TRPC1/C5 channel activity through a Ca2+- and PKC-dependent mechanism in native vascular myocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

TRPC1 proteins confer PKC and phosphoinositol activation on native heteromeric TRPC1/C5 channels in vascular smooth muscle: comparative study of wild-type and TRPC1-/- mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

The constitutive function of native TRPC3 channels modulates vascular cell adhesion molecule-1 expression in coronary endothelial cells through nuclear factor kappaB signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Orai1 and STIM reconstitute store-operated calcium channel function

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Loss of sex discrimination and male-male aggression in mice deficient for TRP2

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

NMDA receptor-dependent synaptic activation of TRPC channels in olfactory bulb granule cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Mechanism of stretch-induced activation of the mechanotransducer zyxin in vascular cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Requirement for non-regulated, constitutive calcium influx in macrophage survival signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Impairment of survival signaling and efferocytosis in TRPC3-deficient macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

The membrane topology of human transient receptor potential 3 as inferred from glycosylation-scanning mutagenesis and epitope immunocytochemistry.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Transient receptor potential channels regulate myogenic tone of resistance arteries

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Canonical transient receptor potential channel subtype 3-mediated hair cell Ca(2+) entry regulates sound transduction and auditory neurotransmission.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Melanopsin signalling in mammalian iris and retina

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Severely blunted allergen-induced pulmonary Th2 cell response and lung hyperresponsiveness in type 1 transient receptor potential channel-deficient mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

SOAR and the polybasic STIM1 domains gate and regulate Orai channels

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Role of TRPC1 channel in skeletal muscle function

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Trpc1 ion channel modulates phosphatidylinositol 3-kinase/Akt pathway during myoblast differentiation and muscle regeneration.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

STIM1 gates TRPC channels, but not Orai1, by electrostatic interaction

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-05161-1_14

10.1007/978-3-319-05161-1_14

31 March 2020

Identifiers

DOI

1 reference

31 August 2017

1 reference

PubMed ID

24961980