Microglia and inflammation: conspiracy, controversy or control? (Q38227727)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25008043%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Microglia and inflammation: conspiracy, controversy or control? (English)

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9 March 2020

0 references

1

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9 March 2020

Leonor Miller-Fleming

series ordinal

2

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9 March 2020

author name string

Teresa F Pais

series ordinal

3

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9 March 2020

publication date

10 July 2014

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Cellular and Molecular Life Sciences

9 March 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25008043%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

volume

71

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9 March 2020

page(s)

3969-3985

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9 March 2020

issue

20

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https://scigraph.springernature.com/pub.10.1007/s00018-014-1670-8

9 March 2020

exact match

0 references

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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TGF-beta1 upregulates CX3CR1 expression and inhibits fractalkine-stimulated signaling in rat microglia

21 January 2018

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21 January 2018

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21 January 2018

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Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis

21 January 2018

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Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase.

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Redox regulation of glial inflammatory response to lipopolysaccharide and interferongamma

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The transcription factor Nrf2 is a therapeutic target against brain inflammation

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Transcription factor Nrf2 suppresses LPS-induced hyperactivation of BV-2 microglial cells

21 January 2018

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MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS

21 January 2018

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Dysregulated microRNAs in amyotrophic lateral sclerosis microglia modulate genes linked to neuroinflammation.

21 January 2018

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MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α-PU.1 pathway.

21 January 2018

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Translating the Histone Code

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Acetylation and deacetylation of non-histone proteins

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Histone deacetylase (HDAC) inhibitors reduce the glial inflammatory response in vitro and in vivo

21 January 2018

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Histone deacetylase inhibition modulates kynurenine pathway activation in yeast, microglia, and mice expressing a mutant huntingtin fragment.

21 January 2018

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The diversity of histone versus nonhistone sirtuin substrates.

21 January 2018

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SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

21 January 2018

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Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

21 January 2018

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SIRT2 regulates NF-κB dependent gene expression through deacetylation of p65 Lys310

21 January 2018

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SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

21 January 2018

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The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility

21 January 2018

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The NAD-dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation.

21 January 2018

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Engineered stem cell-derived microglia as therapeutic vehicle for experimental autoimmune encephalomyelitis

21 January 2018

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Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs.

21 January 2018

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Celecoxib attenuates systemic lipopolysaccharide-induced brain inflammation and white matter injury in the neonatal rats

21 January 2018

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Nonsteroidal anti-inflammatory drugs for the prevention of Alzheimer's disease: a systematic review

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Non-steroidal anti-inflammatory drugs (NSAIDs) and other anti-inflammatory agents in the treatment of neurodegenerative disease

21 January 2018

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Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial

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Rofecoxib: no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study

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The promise of minocycline in neurology.

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Minocycline: stain devil?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Clinical potential of minocycline for neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Minocycline blocks nitric oxide-induced neurotoxicity by inhibition p38 MAP kinase in rat cerebellar granule neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Minocycline prevents glutamate-induced apoptosis of cerebellar granule neurons by differential regulation of p38 and Akt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Inhibition of microglial activation protects hippocampal neurogenesis and improves cognitive deficits in a transgenic mouse model for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Minocycline affects microglia activation, Abeta deposition, and behavior in APP-tg mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Inhibition of autoimmune encephalomyelitis by a tetracycline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Minocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC)alpha/betaII

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Prospects for minocycline neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Minocycline reduces gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Visualization and genetic modification of resident brain microglia using lentiviral vectors regulated by microRNA-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Anti-inflammatory therapy in chronic disease: challenges and opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Tumor necrosis factor-alpha expression in ischemic neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Tumor necrosis factor-alpha messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Serum TNF-alpha levels are increased and correlate negatively with free IGF-I in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Intranigral lentiviral delivery of dominant-negative TNF attenuates neurodegeneration and behavioral deficits in hemiparkinsonian rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

CD200 fusion protein decreases microglial activation in the hippocampus of aged rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Selective targeting of microglia by quantum dots.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Wild-type microglia arrest pathology in a mouse model of Rett syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Brain-specific gene expression by immortalized microglial cell-mediated gene transfer in the mammalian brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Distribution of the Immune Inhibitory Molecules CD200 and CD200R in the Normal Central Nervous System and Multiple Sclerosis Lesions Suggests Neuron-Glia and Glia-Glia Interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Inflammatory Signals Induce Neurotrophin Expression in Human Microglial Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1670-8

Elevated expression of fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) in the dorsal root ganglia and spinal cord in experimental autoimmune encephalomyelitis: implications in multiple sclerosis-induced neuropathic pain.

21 January 2018

1 reference

12 December 2020

Pilot study of minocycline in relapsing-remitting multiple sclerosis

1 reference

12 December 2020

Pharmacotherapeutics of the newer tetracyclines

1 reference

12 December 2020

miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production

1 reference

12 December 2020

Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared

1 reference

12 December 2020

Potential of tetracyclines to modify cartilage breakdown in osteoarthritis

1 reference

12 December 2020

Protective effects of an anti-inflammatory cytokine, interleukin-4, on motoneuron toxicity induced by activated microglia

1 reference

12 December 2020

CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells

1 reference

12 December 2020

Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH

1 reference

12 December 2020

Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1)

1 reference

12 December 2020

Microglial calcium signal acts as a rapid sensor of single neuron damage in vivo

1 reference

12 December 2020

The endotoxin-induced neuroinflammation model of Parkinson's disease.

1 reference

12 December 2020

Vasoactive intestinal peptide and pituitary adenylyl cyclase-activating polypeptide inhibit tumor necrosis factor-alpha production in injured spinal cord and in activated microglia via a cAMP-dependent pathway

1 reference

12 December 2020

Characterization of fractalkine in rat brain cells: migratory and activation signals for CX3CR-1-expressing microglia

1 reference

12 December 2020

CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase

1 reference

12 December 2020

The clinical response to minocycline in multiple sclerosis is accompanied by beneficial immune changes: a pilot study

1 reference

12 December 2020

Pharmacologic suppression of neuronal oxidative damage and dendritic degeneration following direct activation of glial innate immunity in mouse cerebrum

1 reference

12 December 2020

Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia.

1 reference

12 December 2020

Cholinergic agonists increase intracellular Ca2+ in cultured human microglia

1 reference

12 December 2020

Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

1 reference

12 December 2020

Microgliosis: the questions shape the answers

1 reference

12 December 2020

Formation of hetero-oligomeric complexes of type I and type II receptors for transforming growth factor-beta.

1 reference

12 December 2020

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

1 reference

12 December 2020

Endogenous transforming growth factor beta 1 suppresses inflammation and promotes survival in adult CNS

1 reference

12 December 2020

Vasoactive intestinal peptide protects against beta-amyloid-induced neurodegeneration by inhibiting microglia activation at multiple levels

1 reference

12 December 2020

Neuroprotective role of IL-4 against activated microglia

1 reference

12 December 2020

Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures

1 reference

12 December 2020

Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity.

1 reference

12 December 2020

Activated microglia mediate neuronal cell injury via a nitric oxide mechanism

1 reference

12 December 2020

Inflammatory signals induce neurotrophin expression in human microglial cells

1 reference

12 December 2020