Exploring the link between ceramide and ionizing radiation (Q38240473)

31 August 2017

title

Exploring the link between ceramide and ionizing radiation (English)

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31 August 2017

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1

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4 June 2020

Alessandro Prinetti

5

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4 June 2020

Rosaria Bassi

6

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4 June 2020

Sandro Sonnino

7

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4 June 2020

author name string

Valentina Murdica

2

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4 June 2020

Nicoletta Loberto

3

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4 June 2020

Maura Samarani

4

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4 June 2020

publication date

1 October 2014

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31 August 2017

published in

Glycoconjugate Journal

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4 June 2020

volume

31

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4 June 2020

issue

6-7

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4 June 2020

page(s)

449-459

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Ataxia telangiectasia-mutated gene product inhibits DNA damage-induced apoptosis via ceramide synthase

4 June 2020

cites work

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12 December 2020

Signal transduction through lipid second messengers

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12 December 2020

Ceramide-induced inhibition of T lymphocyte voltage-gated potassium channel is mediated by tyrosine kinases

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12 December 2020

Evidence for sialidase hydrolyzing gangliosides GM2 and GM1 in rat liver plasma membrane

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12 December 2020

Increasing endogenous ceramide using inhibitors of sphingolipid metabolism maximizes ionizing radiation-induced mitochondrial injury and apoptotic cell killing

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12 December 2020

Developmental changes in ganglioside composition and synthesis in embryonic rat brain.

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12 December 2020

HIGH DOSE RADIATION DELIVERED BY INTENSITY MODULATED CONFORMAL RADIOTHERAPY IMPROVES THE OUTCOME OF LOCALIZED PROSTATE CANCER

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12 December 2020

Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis

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12 December 2020

Kinase suppressor of Ras is ceramide-activated protein kinase

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12 December 2020

Sphingomyelinases: enzymology and membrane activity

1 reference

12 December 2020

Demonstration of the existence of a second, non-lysosomal glucocerebrosidase that is not deficient in Gaucher disease

1 reference

12 December 2020

Secretory sphingomyelinase, a product of the acid sphingomyelinase gene, can hydrolyze atherogenic lipoproteins at neutral pH. Implications for atherosclerotic lesion development

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12 December 2020

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

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12 December 2020

Plasma membrane production of ceramide from ganglioside GM3 in human fibroblasts

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12 December 2020

The non-lysosomal β-glucosidase GBA2 is a non-integral membrane-associated protein at the endoplasmic reticulum (ER) and Golgi

1 reference

12 December 2020

De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1.

1 reference

12 December 2020

Increased radiation sensitivity of head and neck squamous cell carcinoma with sphingosine kinase 1 inhibition.

1 reference

12 December 2020

Sphingolipids--the enigmatic lipid class: biochemistry, physiology, and pathophysiology

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12 December 2020

Ionizing radiations increase the activity of the cell surface glycohydrolases and the plasma membrane ceramide content.

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12 December 2020

Ceramide binds to the CaLB domain of cytosolic phospholipase A2 and facilitates its membrane docking and arachidonic acid release

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12 December 2020

Roles of plasma membrane-associated sialidase NEU3 in human cancers.

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12 December 2020

Cytosolic sialidase Neu2 upregulation during PC12 cells differentiation

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12 December 2020

Ceramide activates the stress-activated protein kinases

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12 December 2020

Acid ceramidase upregulation in prostate cancer cells confers resistance to radiation: AC inhibition, a potential radiosensitizer

1 reference

12 December 2020

Plasma membrane-associated sialidase is up-regulated in renal cell carcinoma and promotes interleukin-6-induced apoptosis suppression and cell motility

1 reference

12 December 2020

The cellular trafficking and zinc dependence of secretory and lysosomal sphingomyelinase, two products of the acid sphingomyelinase gene

1 reference

12 December 2020

Purification and characterization of a cytosolic broad specificity beta-glucosidase from human liver.

1 reference

12 December 2020

Acid ceramidase-mediated production of sphingosine 1-phosphate promotes prostate cancer invasion through upregulation of cathepsin B

1 reference

12 December 2020

Sphingomyelin metabolism at the plasma membrane: implications for bioactive sphingolipids

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12 December 2020

Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

1 reference

12 December 2020

Plasma membrane-associated sialidase as a crucial regulator of transmembrane signalling

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12 December 2020

Acidic and neutral sialidase in the erythrocyte membrane of type 2 diabetic patients

1 reference

12 December 2020

Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress

1 reference

12 December 2020

The roles of neutral sphingomyelinases in neurological pathologies

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12 December 2020

Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy

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12 December 2020

Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphinganine N-acyltransferase in mouse liver

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12 December 2020

Lack of ceramide generation in TF-1 human myeloid leukemic cells resistant to ionizing radiation

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12 December 2020

Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells.

1 reference

12 December 2020

Modification of sialidase levels and sialoglycoconjugate pattern during erythroid and erytroleukemic cell differentiation

1 reference

12 December 2020

Human vascular endothelial cells are a rich and regulatable source of secretory sphingomyelinase. Implications for early atherogenesis and ceramide-mediated cell signaling

1 reference

12 December 2020

Radiation-induced acid ceramidase confers prostate cancer resistance and tumor relapse

1 reference

12 December 2020

Ceramide and cell death receptor clustering

1 reference

12 December 2020

Up-regulation of plasma membrane-associated ganglioside sialidase (Neu3) in human colon cancer and its involvement in apoptosis suppression

1 reference

12 December 2020

Stimulation of CD95 (Fas) blocks T lymphocyte calcium channels through sphingomyelinase and sphingolipids.

1 reference

12 December 2020

The therapeutic potential of modulating the ceramide/sphingomyelin pathway

1 reference

12 December 2020

Compartmentalization of ceramide signaling: physical foundations and biological effects

1 reference

12 December 2020

Radiation-induced apoptosis of endothelial cells in the murine central nervous system: protection by fibroblast growth factor and sphingomyelinase deficiency

1 reference

12 December 2020

Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes

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12 December 2020

Loss of ceramide production confers resistance to radiation-induced apoptosis

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12 December 2020

Recent development in mammalian sialidase molecular biology

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12 December 2020

Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha

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12 December 2020

Alkaline sphingomyelinases and ceramidases of the gastrointestinal tract

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12 December 2020

Identification of plasma membrane associated mature β-hexosaminidase A, active towards GM2 ganglioside, in human fibroblasts

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12 December 2020

Ceramide enables fas to cap and kill.

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12 December 2020

Role of the ceramide-signaling pathways in ionizing radiation-induced apoptosis

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12 December 2020

Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity.

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12 December 2020

Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1).

1 reference

12 December 2020

An essential role for membrane rafts in the initiation of Fas/CD95-triggered cell death in mouse thymocytes

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12 December 2020

Role of plasma membrane ganglioside sialidase of human neuroblastoma cells in growth control and differentiation

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12 December 2020

Ceramide-binding and activation defines protein kinase c-Raf as a ceramide-activated protein kinase

1 reference

12 December 2020

Overexpressing cell surface beta 1.4-galactosyltransferase in PC12 cells increases neurite outgrowth on laminin.

1 reference

12 December 2020

Sphingolipid metabolism diseases

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12 December 2020

Ceramide induces activation of the mitochondrial/caspases pathway in Jurkat and SCC61 cells sensitive to gamma-radiation but activation of this sequence is defective in radioresistant SQ20B cells

1 reference

12 December 2020

Remodeling of sphingolipids by plasma membrane associated enzymes.

1 reference

12 December 2020

Intracellular trafficking of cholesterol monitored with a cyclodextrin

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12 December 2020

Enzymes of sphingolipid metabolism: from modular to integrative signaling

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12 December 2020

BAD Enables Ceramide to Signal Apoptosis via Ras and Raf-1

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12 December 2020

Radiation and ceramide-induced apoptosis

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12 December 2020

A radiometric assay for ganglioside sialidase applied to the determination of the enzyme subcellular location in cultured human fibroblasts

1 reference

12 December 2020

Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice.

1 reference

12 December 2020

Role of sphingomyelinase and ceramide in modulating rafts: do biophysical properties determine biologic outcome?

1 reference

12 December 2020

Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans

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12 December 2020

Activity of plasma membrane beta-galactosidase and beta-glucosidase

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12 December 2020

Importance of C1B domain for lipid messenger-induced targeting of protein kinase C.

1 reference

12 December 2020

Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells

1 reference

12 December 2020