Genome engineering via TALENs and CRISPR/Cas9 systems: challenges and perspectives (Q38253811)

1 September 2017

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title

Genome engineering via TALENs and CRISPR/Cas9 systems: challenges and perspectives (English)

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1 September 2017

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25250853%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

author name string

Agnieszka Piatek

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25250853%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Charles Neal Stewart

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25250853%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

publication date

1 October 2014

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Plant Biotechnology Journal

1 September 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25250853%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

12

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25250853%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

issue

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25250853%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

page(s)

1006-1014

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25250853%20AND%20SRC:MED&resulttype=core&format=json

From sequence to phenotype: reverse genetics in Drosophila melanogaster

3 June 2020

cites work

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In vivo genome editing using a high-efficiency TALEN system

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Xanthomonas AvrBs3 family-type III effectors: discovery and function

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Breaking the code of DNA binding specificity of TAL-type III effectors

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TAL effectors: customizable proteins for DNA targeting

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Three-dimensional modeling of the I-TevI homing endonuclease catalytic domain, a GIY-YIG superfamily member, using NMR restraints and Monte Carlo dynamics.

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Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century

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Efficient TALEN-mediated gene knockout in livestock

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Genome Engineering With Zinc-Finger Nucleases

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Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

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A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly

21 January 2018

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Targeting DNA double-strand breaks with TAL effector nucleases

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Classification and evolution of type II CRISPR-Cas systems

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Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains

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Multiplex genome engineering using CRISPR/Cas systems

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Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering in Arabidopsis thaliana.

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Multigeneration analysis reveals the inheritance, specificity, and patterns of CRISPR/Cas-induced gene modifications in Arabidopsis

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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

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Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

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Transcriptional activators of human genes with programmable DNA-specificity

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Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

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CRISPRs extending their reach: prokaryotic RNAi protein Cas9 recruited for gene regulation

21 January 2018

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Transgene regulation in plants by alternative splicing of a suicide exon

21 January 2018

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DNA targeting specificity of RNA-guided Cas9 nucleases

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Development and applications of CRISPR-Cas9 for genome engineering

21 January 2018

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation

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Programmable DNA cleavage in vitro by Cas9.

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A guide to genome engineering with programmable nucleases

21 January 2018

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Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

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Monomeric site-specific nucleases for genome editing

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Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease.

21 January 2018

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Breaking the DNA-binding code of Ralstonia solanacearum TAL effectors provides new possibilities to generate plant resistance genes against bacterial wilt disease

21 January 2018

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TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

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Rapid and highly efficient construction of TALE-based transcriptional regulators and nucleases for genome modification

21 January 2018

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High-efficiency TALEN-based gene editing produces disease-resistant rice.

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Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9.

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Characterization and DNA-binding specificities of Ralstonia TAL-like effectors

21 January 2018

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Efficient and specific modifications of the Drosophila genome by means of an easy TALEN strategy

21 January 2018

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Advanced genetic tools for plant biotechnology

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Synthetic TAL effectors for targeted enhancement of transgene expression in plants

21 January 2018

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Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays

21 January 2018

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De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks

21 January 2018

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Targeted transcriptional repression using a chimeric TALE-SRDX repressor protein.

21 January 2018

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RNA-guided human genome engineering via Cas9

21 January 2018

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Nontransgenic Genome Modification in Plant Cells

21 January 2018

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A TALE nuclease architecture for efficient genome editing

21 January 2018

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Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors

21 January 2018

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Assembly of custom TALE-type DNA binding domains by modular cloning

21 January 2018

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Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells

21 January 2018

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Site-specific DNA cleavage by artificial zinc finger-type nuclease with cerium-binding peptide.

21 January 2018

1 reference

Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease

21 January 2018

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Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

21 January 2018

1 reference

Gene targeting using zinc finger nucleases

21 January 2018

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Unexpected failure rates for modular assembly of engineered zinc fingers

21 January 2018

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

21 January 2018

1 reference

FLASH assembly of TALENs for high-throughput genome editing

21 January 2018

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A single plant resistance gene promoter engineered to recognize multiple TAL effectors from disparate pathogens

21 January 2018

1 reference

CRISPR-Cas systems for editing, regulating and targeting genomes

21 January 2018

1 reference

A transcription activator-like effector toolbox for genome engineering

21 January 2018

1 reference

A ligation-independent cloning technique for high-throughput assembly of transcription activator–like effector genes

21 January 2018

1 reference

Rapid and efficient gene modification in rice and Brachypodium using TALENs

21 January 2018

1 reference

Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage

21 January 2018

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Precise genome modification in the crop species Zea mays using zinc-finger nucleases

21 January 2018

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Forty years with homologous recombination

21 January 2018

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DNA-guided DNA interference by a prokaryotic Argonaute

21 January 2018

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High-frequency modification of plant genes using engineered zinc-finger nucleases

21 January 2018

1 reference

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

21 January 2018

1 reference

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

21 January 2018

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Plant genome engineering with sequence-specific nucleases

21 January 2018

1 reference

Does CRISPR-Cas open new possibilities for patents or present a moral maze?

21 January 2018

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Assembly of designer TAL effectors by Golden Gate cloning

21 January 2018

1 reference

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

21 January 2018

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Natural zinc ribbon HNH endonucleases and engineered zinc finger nicking endonuclease

21 January 2018

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Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

21 January 2018

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Transcription activator-like effector nucleases enable efficient plant genome engineering.

21 January 2018

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