Inhibitors of voltage-gated sodium channel Nav1.7: patent applications since 2010. (Q38265475)

1 September 2017

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title

Inhibitors of voltage-gated sodium channel Nav1.7: patent applications since 2010. (English)

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1 September 2017

Shaoyi Sun

1

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PubMed ID

25374320

1 September 2017

Charles J Cohen

series ordinal

2

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PubMed ID

25374320

1 September 2017

Christoph M Dehnhardt

series ordinal

3

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1 September 2017

1 September 2014

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Pharmaceutical patent analyst

1 September 2017

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1 September 2017

3

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5

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1 September 2017

509-521

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An SCN9A channelopathy causes congenital inability to experience pain

1 September 2017

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Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations

21 January 2018

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Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons

21 January 2018

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SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes

21 January 2018

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Mouse model of SCN5A-linked hereditary Lenègre's disease: age-related conduction slowing and myocardial fibrosis

21 January 2018

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Common sodium channel promoter haplotype in asian subjects underlies variability in cardiac conduction.

21 January 2018

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A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.

21 January 2018

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Structural determinants of drugs acting on the Nav1.8 channel

21 January 2018

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Characterization of a new class of potent inhibitors of the voltage-gated sodium channel Nav1.7.

21 January 2018

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Identification of a potent, state-dependent inhibitor of Nav1.7 with oral efficacy in the formalin model of persistent pain.

21 January 2018

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Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels

21 January 2018

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Pharmacology of 2-[4-(4-chloro-2-fluorophenoxy)phenyl]-pyrimidine-4-carboxamide: a potent, broad-spectrum state-dependent sodium channel blocker for treating pain states.

21 January 2018

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A novel slow-inactivation-specific ion channel modulator attenuates neuropathic pain.

21 January 2018

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Function and solution structure of huwentoxin-IV, a potent neuronal tetrodotoxin (TTX)-sensitive sodium channel antagonist from Chinese bird spider Selenocosmia huwena

21 January 2018

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Two tarantula peptides inhibit activation of multiple sodium channels

21 January 2018

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21 January 2018

Identifiers

DOI

10.4155/PPA.14.39

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1 September 2017

1 reference

PubMed ID

25374320