TRIF signaling is essential for TLR4-driven IgE class switching (Q38266449)

1 September 2017

TRIF signaling is essential for TLR4-driven IgE class switching (English)

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1 September 2017

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7

Shizuo Akira

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Douglas T Golenbock

9

object named as

Douglas T Golenbock

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1 September 2017

Erin Janssen

1

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1 September 2017

Esra Ozcan

2

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1 September 2017

Kyriaki Liadaki

3

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1 September 2017

Haifa H Jabara

4

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1 September 2017

John Manis

5

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Sumana Ullas

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1 September 2017

Katherine A Fitzgerald

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Raif S Geha

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1 September 2017

language of work or name

English

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publication date

14 February 2014

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1 September 2017

Journal of Immunology

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1 September 2017

192

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6

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2651-2658

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describes a project that uses

1 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3952935/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Immunoglobulin class-switch DNA recombination: induction, targeting and beyond

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Localisation and trafficking of Toll-like receptors: an important mode of regulation.

6 September 2017

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Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF.

6 September 2017

1 reference

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Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity

6 September 2017

1 reference

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The role of activation-induced cytidine deaminase in antibody diversification, immunodeficiency, and B-cell malignancies

6 September 2017

1 reference

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TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952935

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

6 September 2017

1 reference

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Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

6 September 2017

1 reference

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Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction

6 September 2017

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

6 September 2017

1 reference

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

6 September 2017

1 reference

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IL-4/IL-13 signaling beyond JAK/STAT

6 September 2017

1 reference

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Functional synergism of STAT6 with either NF-kappa B or PU.1 to mediate IL-4-induced activation of IgE germline gene transcription

6 September 2017

1 reference

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The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins

6 September 2017

1 reference

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B cells lacking RelB are defective in proliferative responses, but undergo normal B cell maturation to Ig secretion and Ig class switching

6 September 2017

1 reference

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Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50.

6 September 2017

1 reference

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Regulation of IgG1 and IgE synthesis by interleukin 4 in mouse B cells

6 September 2017

1 reference

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Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952935

Structure and expression of germ line immunoglobulin heavy-chain epsilon transcripts: interleukin-4 plus lipopolysaccharide-directed switching to C epsilon

6 September 2017

1 reference

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Structure and expression of murine germ-line immunoglobulin epsilon heavy chain transcripts induced by interleukin 4.

6 September 2017

1 reference

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Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.

6 September 2017

1 reference

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Inhibitory action of novel aromatic diamine compound on lipopolysaccharide-induced nuclear translocation of NF-kappaB without affecting IkappaB degradation

14 September 2017

1 reference

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Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB.

14 September 2017

1 reference

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Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40.

14 September 2017

1 reference

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PU.1 can recruit BCL6 to DNA to repress gene expression in germinal center B cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952935

STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952935

IL-4 induces the specific rearrangement of gamma 1 genes on the expressed and unexpressed chromosomes of lipopolysaccharide-activated normal murine B cells.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952935

TLR4- and TRIF-dependent stimulation of B lymphocytes by peptide liposomes enables T cell-independent isotype switch in mice

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952935

Cell division number regulates IgG1 and IgE switching of B cells following stimulation by CD40 ligand and IL-4.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952935

Germline and productive C epsilon gene expression during in vivo IgE responses

31 August 2018

1 reference

12 December 2020

B cells from p50/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching

1 reference

12 December 2020

IL4 and IL13 receptors share the γc chain and activate STAT6, STAT3 and STAT5 proteins in normal human B cells

1 reference

12 December 2020

B cells genetically deficient in the c-Rel transactivation domain have selective defects in germline CH transcription and Ig class switching

1 reference

12 December 2020

Unresponsiveness of MyD88-deficient mice to endotoxin

1 reference

12 December 2020

Characterization of TLR4-mediated auto-antibody production in a mouse model of histidyl-tRNA synthetase-induced myositis

1 reference

12 December 2020

The binding site for TRAF2 and TRAF3 but not for TRAF6 is essential for CD40-mediated immunoglobulin class switching

1 reference

12 December 2020

Essential role of Id2 in negative regulation of IgE class switching

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1300909

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1 September 2017

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1 September 2017

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