Roles of oxidative stress, adiponectin, and nuclear hormone receptors in obesity-associated insulin resistance and cardiovascular risk (Q38267491)

1 September 2017

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title

Roles of oxidative stress, adiponectin, and nuclear hormone receptors in obesity-associated insulin resistance and cardiovascular risk (English)

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1 September 2017

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Morihiro Matsuda

1

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PubMed ID

25390017

1 September 2017

Iichiro Shimomura

series ordinal

2

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1 September 2017

1 August 2014

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Hormone Molecular Biology and Clinical Investigation

1 September 2017

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1 September 2017

19

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1 September 2017

75-88

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1 September 2017

2

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Both liver-X receptor (LXR) isoforms control energy expenditure by regulating brown adipose tissue activity

1 September 2017

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

The nuclear orphan receptor COUP-TFII plays an essential role in adipogenesis, glucose homeostasis, and energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Remnant lipoprotein particles induce apoptosis in endothelial cells by NAD(P)H oxidase-mediated production of superoxide and cytokines via lectin-like oxidized low-density lipoprotein receptor-1 activation: prevention by cilostazol

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Essential role of stress hormone signaling in cardiomyocytes for the prevention of heart disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Adiponectin-mediated modulation of hypertrophic signals in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

The concept of metabolic syndrome: contribution of visceral fat accumulation and its molecular mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

LXRs regulate the balance between fat storage and oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Adiponectin protein exists in aortic endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Pivotal role of the mineralocorticoid receptor in corticosteroid-induced adipogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

AMP-activated protein kinase deficiency enhances myocardial ischemia/reperfusion injury but has minimal effect on the antioxidant/antinitrative protection of adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partner

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in obesity-induced hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Obesity is associated with macrophage accumulation in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Role of oxidative modifications in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

The orphan nuclear receptor SHP regulates PGC-1alpha expression and energy production in brown adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Mineralocorticoid receptors: distribution and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Mineralocorticoid receptor blockade reverses obesity-related changes in expression of adiponectin, peroxisome proliferator-activated receptor-gamma, and proinflammatory adipokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

The role of oxidative stress in the pathogenesis of diabetic vascular complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Hypoadiponectinemia is an independent risk factor for hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Liver X receptors are regulators of adipocyte gene expression but not differentiation: identification of apoD as a direct target

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

The role of orphan nuclear receptors in the regulation of cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Human catalase gene is regulated by peroxisome proliferator activated receptor-gamma through a response element distinct from that of mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Reduced cardioprotective action of adiponectin in high-fat diet-induced type II diabetic mice and its underlying mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Superoxide generation in directional coronary atherectomy specimens of patients with angina pectoris: important role of NAD(P)H oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Protection against oxidative stress-induced insulin resistance in rat L6 muscle cells by mircomolar concentrations of alpha-lipoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Human fat cells possess a plasma membrane-bound H2O2-generating system that is activated by insulin via a mechanism bypassing the receptor kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: effects of short- and long-term simvastatin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Adiponectin as a biomarker of the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Visceral fat accumulation and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Dysregulation of adipose glutathione peroxidase 3 in obesity contributes to local and systemic oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

The peroxisome proliferator-activated receptor beta/delta agonist, GW501516, regulates the expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

NAD(P)H oxidase: role in cardiovascular biology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Aldosterone activates vascular p38MAP kinase and NADPH oxidase via c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Effects of peroxisome proliferator-activated receptor ligands, bezafibrate and fenofibrate, on adiponectin level

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Low adiponectin levels are associated with atherogenic dyslipidemia and lipid-rich plaque in nondiabetic coronary arteries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

The pathobiology of diabetic complications: a unifying mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Mineralocorticoid receptors in the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Antiadipogenic effects of the mineralocorticoid receptor antagonist drospirenone: potential implications for the treatment of metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Increased oxidative stress in obesity and its impact on metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Predictive value of adiponectin in patients with multivessel coronary atherosclerosis detected on computed tomography angiography

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Oxidative stress and diabetic cardiovascular complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Activation of farnesoid X receptor prevents atherosclerotic lesion formation in LDLR-/- and apoE-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Systemic oxidative stress is associated with visceral fat accumulation and the metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI-2014-0001

21 January 2018

Identifiers

DOI

10.1515/HMBCI-2014-0001

1 reference

1 September 2017

1 reference

PubMed ID

25390017