Enzalutamide: targeting the androgen signalling pathway in metastatic castration-resistant prostate cancer (Q38276818)

1 September 2017

9 references

3 April 2019

25 June 2019

17 November 2019

21 December 2019

2 August 2020

26 August 2020

26 October 2020

13 November 2020

25 January 2021

Enzalutamide: targeting the androgen signalling pathway in metastatic castration-resistant prostate cancer (English)

1 reference

castration-resistant prostatic neoplasm

1 September 2017

9 references

3 April 2019

25 June 2019

17 November 2019

21 December 2019

2 August 2020

26 August 2020

26 October 2020

13 November 2020

25 January 2021

1 reference

17 November 2019

intracellular receptor

1 reference

21 December 2019

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26 August 2020

antineoplastic resistance

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26 October 2020

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13 November 2020

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25 January 2021

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Jack Schalken

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1 September 2017

John M Fitzpatrick

series ordinal

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language of work or name

1 reference

27 March 2015

1 reference

1 September 2017

1 February 2016

9 references

3 April 2019

25 June 2019

17 November 2019

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2 August 2020

26 August 2020

26 October 2020

13 November 2020

25 January 2021

10 references

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17 November 2019

21 December 2019

2 August 2020

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13 November 2020

25 January 2021

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Creative Commons Attribution-NonCommercial-NoDerivatives

1 September 2017

9 references

3 April 2019

25 June 2019

17 November 2019

21 December 2019

2 August 2020

26 August 2020

26 October 2020

13 November 2020

25 January 2021

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cites work

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6 September 2017

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6 September 2017

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6 September 2017

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Molecular characterization of enzalutamide-treated bone metastatic castration-resistant prostate cancer

6 September 2017

1 reference

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Enzalutamide in metastatic prostate cancer before chemotherapy

6 September 2017

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6 September 2017

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Taxane mechanisms of action: potential implications for treatment sequencing in metastatic castration-resistant prostate cancer

6 September 2017

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Constitutively active androgen receptor variants upregulate expression of mesenchymal markers in prostate cancer cells

6 September 2017

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Clinical activity of abiraterone acetate in patients with metastatic castration-resistant prostate cancer progressing after enzalutamide

6 September 2017

1 reference

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Overcoming mutation-based resistance to antiandrogens with rational drug design

6 September 2017

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6 September 2017

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Abiraterone in metastatic prostate cancer without previous chemotherapy

6 September 2017

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6 September 2017

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Increased survival with enzalutamide in prostate cancer after chemotherapy

6 September 2017

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Abiraterone and other novel androgen-directed strategies for the treatment of prostate cancer: a new era of hormonal therapies is born.

6 September 2017

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Outsmarting androgen receptor: creative approaches for targeting aberrant androgen signaling in advanced prostate cancer

6 September 2017

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ARN-509: a novel antiandrogen for prostate cancer treatment

6 September 2017

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Androgen receptor variants occur frequently in castration resistant prostate cancer metastases

6 September 2017

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6 September 2017

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Characterising the castration-resistant prostate cancer population: a systematic review

6 September 2017

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6 September 2017

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Taxane-induced blockade to nuclear accumulation of the androgen receptor predicts clinical responses in metastatic prostate cancer

6 September 2017

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Abiraterone and increased survival in metastatic prostate cancer

6 September 2017

1 reference

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Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial

6 September 2017

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Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor

6 September 2017

1 reference

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Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

6 September 2017

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Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study

6 September 2017

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6 September 2017

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Anti-androgens and androgen-depleting therapies in prostate cancer: new agents for an established target

6 September 2017

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Castration-resistant prostate cancer: locking up the molecular escape routes

6 September 2017

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Castration-resistant prostate cancer: targeting androgen metabolic pathways in recurrent disease

6 September 2017

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Development of a second-generation antiandrogen for treatment of advanced prostate cancer

6 September 2017

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Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer.

6 September 2017

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Targeted therapy for advanced prostate cancer: inhibition of the PI3K/Akt/mTOR pathway

6 September 2017

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Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer

6 September 2017

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Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer

6 September 2017

1 reference

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Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer

6 September 2017

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Androgen receptor in prostate cancer

6 September 2017

1 reference

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Molecular determinants of resistance to antiandrogen therapy

6 September 2017

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Molecular biology of the androgen receptor

6 September 2017

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Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells

6 September 2017

1 reference

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In vivo amplification of the androgen receptor gene and progression of human prostate cancer

6 September 2017

1 reference

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Androgen receptor defects: historical, clinical, and molecular perspectives

6 September 2017

1 reference

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Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: a rationale for increasing abiraterone exposure or combining with MDV3100.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4744713

Clinical Outcomes of Castration-resistant Prostate Cancer Treatments Administered as Third or Fourth Line Following Failure of Docetaxel and Other Second-line Treatment: Results of an Italian Multicentre Study.

6 September 2017

1 reference

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Molecular processes leading to aberrant androgen receptor signaling and castration resistance in prostate cancer

23 June 2018

1 reference

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Enzalutamide in European and North American men participating in the AFFIRM trial

23 June 2018

1 reference

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Effect of enzalutamide on time to first skeletal-related event, pain, and quality of life in men with castration-resistant prostate cancer: results from the randomised, phase 3 AFFIRM trial

31 August 2018

1 reference

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Activity of cabazitaxel in castration-resistant prostate cancer progressing after docetaxel and next-generation endocrine agents

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4744713

Clinical activity and tolerability of enzalutamide (MDV3100) in patients with metastatic, castration-resistant prostate cancer who progress after docetaxel and abiraterone treatment.

31 August 2018

1 reference

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Enzalutamide treatment in patients with metastatic castration-resistant prostate cancer progressing after chemotherapy and abiraterone acetate.

31 August 2018

1 reference

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Enzalutamide in castration-resistant prostate cancer patients progressing after docetaxel and abiraterone

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4744713

Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100).

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4744713

Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: a phase III trial (CALGB 9583).

31 August 2018

1 reference

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Maximum androgen blockade in advanced prostate cancer: an overview of the randomised trials

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FBJU.13123

Antitumour activity of enzalutamide (MDV3100) in patients with metastatic castration-resistant prostate cancer (CRPC) pre-treated with docetaxel and abiraterone

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FBJU.13123

Clinical states in prostate cancer: toward a dynamic model of disease progression

21 January 2018

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12 December 2020

Steroid hormone withdrawal syndromes. Pathophysiology and clinical significance

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12 December 2020

Enzalutamide after docetaxel and abiraterone therapy in metastatic castration-resistant prostate cancer

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12 December 2020

Enzalutamide Antitumour Activity Against Metastatic Castration-resistant Prostate Cancer Previously Treated with Docetaxel and Abiraterone: A Multicentre Analysis

1 reference

12 December 2020

Targeting the Androgen Receptor Confers In Vivo Cross-resistance Between Enzalutamide and Docetaxel, But Not Cabazitaxel, in Castration-resistant Prostate Cancer

1 reference

12 December 2020

Improved outcomes in elderly patients with metastatic castration-resistant prostate cancer treated with the androgen receptor inhibitor enzalutamide: results from the phase III AFFIRM trial

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12 December 2020

Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer

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12 December 2020

Enzalutamide after failure of docetaxel and abiraterone in metastatic castrate-resistant prostate cancer

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12 December 2020

Maximum androgen blockade in advanced prostate cancer: an overview of the randomised trials. Prostate Cancer Trialists' Collaborative Group

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12 December 2020

Identifiers

DOI

10.1111/BJU.13123

1 reference

1 September 2017

1 reference

1 September 2017

PubMed publication ID

25818596

1 reference