Transforming growth factor-beta-stimulated endocardial cell transformation is dependent on Par6c regulation of RhoA. (Q38291432)

1 September 2017

Transforming growth factor-beta-stimulated endocardial cell transformation is dependent on Par6c regulation of RhoA. (English)

1 reference

1 September 2017

2

Jeffrey L Wrana

1 reference

1 September 2017

Todd A Townsend

1

1 reference

1 September 2017

George E Davis

series ordinal

3

1 reference

1 September 2017

Joey V Barnett

series ordinal

4

1 reference

1 September 2017

language of work or name

English

0 references

publication date

14 March 2008

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Journal of Biological Chemistry

1 September 2017

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1 September 2017

283

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1 September 2017

20

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1 September 2017

13834-13841

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Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis

1 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376225

Coronary vessel development is dependent on the type III transforming growth factor beta receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376225

Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376225

Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376225

Regulation of Par6 by extracellular signals

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376225

Rho GTPases: biochemistry and biology

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376225

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376225

Ubiquitination of RhoA by Smurf1 promotes neurite outgrowth

6 September 2017

1 reference

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Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro

6 September 2017

1 reference

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Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis

6 September 2017

1 reference

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Bone morphogenetic protein-2 can mediate myocardial regulation of atrioventricular cushion mesenchymal cell formation in mice

6 September 2017

1 reference

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Regulation of cell polarity and protrusion formation by targeting RhoA for degradation

6 September 2017

1 reference

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TGF-beta-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest

6 September 2017

1 reference

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Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

6 September 2017

1 reference

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

6 September 2017

1 reference

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Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways

6 September 2017

1 reference

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

6 September 2017

1 reference

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Early events in valvulogenesis: a signaling perspective

6 September 2017

1 reference

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Rho GTPases and the regulation of endothelial permeability

6 September 2017

1 reference

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RhoA is highly up‐regulated in the process of early heart development of the chick and important for normal embryogenesis

6 September 2017

1 reference

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The incidence of congenital heart disease

6 September 2017

1 reference

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Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA

6 September 2017

1 reference

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Infective endocarditis in adults

6 September 2017

1 reference

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Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channel

6 September 2017

1 reference

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Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

6 September 2017

1 reference

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Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart

6 September 2017

1 reference

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A simplified system for generating recombinant adenoviruses

6 September 2017

1 reference

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Valvular heart disease associated with fenfluramine-phentermine

6 September 2017

1 reference

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Mechanism of activation of the TGF-beta receptor

6 September 2017

1 reference

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Congenital heart disease: incidence and inheritance.

6 September 2017

1 reference

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Expression cloning and characterization of the TGF-beta type III receptor

6 September 2017

1 reference

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Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-beta receptor system

6 September 2017

1 reference

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Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells

6 September 2017

1 reference

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Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

6 September 2017

1 reference

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Degradation of RhoA by Smurf1 ubiquitin ligase

14 September 2017

1 reference

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Transforming growth factor-beta1-induced expression of smooth muscle marker genes involves activation of PKN and p38 MAPK.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376225

Rac1/Cdc42 and RhoA GTPases antagonistically regulate chondrocyte proliferation, hypertrophy, and apoptosis

14 September 2017

1 reference

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A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

14 September 2017

1 reference

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Involvement of Rho kinase in endothelial barrier maintenance

27 September 2017

1 reference

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Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

23 June 2018

1 reference

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Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases

23 June 2018

1 reference

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Targeted disruption in murine cells reveals variable requirement for Smad4 in transforming growth factor beta-related signaling.

23 June 2018

1 reference

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SMADs: mediators and regulators of TGF-beta signaling

23 June 2018

1 reference

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The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.

23 June 2018

1 reference

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Activin receptor-like kinase 2 and Smad6 regulate epithelial-mesenchymal transformation during cardiac valve formation

23 June 2018

1 reference

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Rac and Rho play opposing roles in the regulation of hypoxia/reoxygenation-induced permeability changes in pulmonary artery endothelial cells

31 August 2018

1 reference

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Rho-associated kinases play a role in endocardial cell differentiation and migration.

31 August 2018

1 reference

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TGFbeta regulates the expression of G alpha(i2) via an effect on the localization of ras.

31 August 2018

1 reference

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p38 mitogen-activated protein kinase is required for TGFbeta-mediated fibroblastic transdifferentiation and cell migration.

31 August 2018

1 reference

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Rho and Rac but not Cdc42 regulate endothelial cell permeability.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376225

Migratory behavior of cardiac cushion tissue cells in a collagen-lattice culture system

31 August 2018

1 reference

12 December 2020

Carcinoid heart disease. Correlation of high serotonin levels with valvular abnormalities detected by cardiac catheterization and echocardiography

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12 December 2020

Antibodies to the Type II TGFbeta receptor block cell activation and migration during atrioventricular cushion transformation in the heart

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12 December 2020

Rho kinases regulate endothelial invasion and migration during valvuloseptal endocardial cushion tissue formation

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TGF beta-mediated RhoA expression is necessary for epithelial-mesenchymal transition in the embryonic chick heart

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The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matrices

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12 December 2020

Identifiers

DOI

10.1074/JBC.M710607200

1 reference

1 September 2017

1 reference

1 September 2017

1 reference