Toll/interleukin-1 receptor (TIR) domain-mediated cellular signaling pathways (Q38309224)

2 September 2017

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title

Toll/interleukin-1 receptor (TIR) domain-mediated cellular signaling pathways (English)

1 reference

2 September 2017

Kannan Badri Narayanan

series ordinal

1

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PubMed ID

25563856

2 September 2017

Hyun Ho Park

series ordinal

2

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2 September 2017

1 February 2015

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2 September 2017

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2 September 2017

20

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2 September 2017

196-209

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2 September 2017

2

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https://scigraph.springernature.com/pub.10.1007/s10495-014-1073-1

2 September 2017

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cites work

A new eye on NLR proteins: focused on clarity or diffused by complexity?

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

21 January 2018

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Regulation of RLR-mediated innate immune signaling--it is all about keeping the balance

21 January 2018

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C-type lectin receptor-induced NF-κB activation in innate immune and inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

TIR, CARD and PYRIN: three domains for an antimicrobial triad

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Innate immune recognition

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Toll-like receptors: critical proteins linking innate and acquired immunity

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Toll-like receptors and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The roles of TLRs, RLRs and NLRs in pathogen recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

21 January 2018

TLRs and innate immunity

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Structures of the toll-like receptor family and its ligand complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Toll-like receptor control of the adaptive immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Regulatory T cells and Toll-like receptors: what is the missing link?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Pathogen recognition and innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Drosophila Toll and IL-1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Immunological and inflammatory functions of the interleukin-1 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The interleukin 1 receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The interleukin-1 receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

TIRAP: an adapter molecule in the Toll signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The Toll-IL-1 receptor adaptor family grows to five members.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The Immune Adaptor Molecule SARM Modulates Tumor Necrosis Factor Alpha Production and Microglia Activation in the Brainstem and Restricts West Nile Virus Pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Identification of essential regions in the cytoplasmic tail of interleukin-1 receptor accessory protein critical for interleukin-1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Structural basis for signal transduction by the Toll/interleukin-1 receptor domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

MyD88, an adapter protein involved in interleukin-1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Crystal structure of TIR domain of TLR6 reveals novel dimeric interface of TIR-TIR interaction for toll-like receptor signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Toll-like receptor 5 forms asymmetric dimers in the absence of flagellin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Structural Insights into TIR Domain Specificity of the Bridging Adaptor Mal in TLR4 Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Identification of critical residues of the MyD88 death domain involved in the recruitment of downstream kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

AP-1 function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

AP-1 as a regulator of cell life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Signal integration by JNK and p38 MAPK pathways in cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Non-canonical IKKs, IKKϵ and TBK1, as novel therapeutic targets in the treatment of non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

IRF3 mediates a TLR3/TLR4-specific antiviral gene program

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Toll-like receptors' two-edged sword: when immunity meets apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

NF-kappaB regulation in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Targeting signal transduction as a strategy to treat inflammatory diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Identification of potential pathway mediation targets in Toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Pyogenic bacterial infections in humans with MyD88 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Toll-like receptors: novel pharmacological targets for the treatment of neurological diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Interactive sites in the MyD88 Toll/interleukin (IL) 1 receptor domain responsible for coupling to the IL1beta signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Targeting TLR4 signaling by TLR4 Toll/IL-1 receptor domain-derived decoy peptides: identification of the TLR4 Toll/IL-1 receptor domain dimerization interface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Interacting neuroendocrine and innate and acquired immune pathways regulate neutrophil mobilization from bone marrow following hemorrhagic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Targeting of antigen to dendritic cells with poly(gamma-glutamic acid) nanoparticles induces antigen-specific humoral and cellular immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Cutting Edge: Differential inhibition of TLR signaling pathways by cell-permeable peptides representing BB loops of TLRs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Differential involvement of BB loops of toll-IL-1 resistance (TIR) domain-containing adapter proteins in TLR4- versus TLR2-mediated signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The TIR/BB-loop mimetic AS-1 protects the myocardium from ischaemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Design, synthesis, and in vitro activity of peptidomimetic inhibitors of myeloid differentiation factor 88.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

RDP58 is a novel and potentially effective oral therapy for ulcerative colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Inflammation and cancer: back to Virchow?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Death receptor-induced cell killing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Suppression of TLR signaling by targeting TIR domain-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The apoptotic signaling pathway activated by Toll-like receptor-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Maturation and release of interleukin-1beta by lipopolysaccharide-primed mouse Schwann cells require the stimulation of P2X7 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Inflammation-mediated dysfunction and apoptosis in pancreatic islet transplantation: implications for intrahepatic grafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

Aspects of the involvement of interleukin-1 and nitric oxide in the pathogenesis of insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

The role of interleukin 1 in acute neurodegeneration and stroke: pathophysiological and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

AP-1 in cell proliferation and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10495-014-1073-1

10.1007/S10495-014-1073-1

21 January 2018

Identifiers

DOI

1 reference

2 September 2017

1 reference

PubMed ID

25563856