High-fat diet induces leptin resistance in leptin-deficient mice (Q38310038)

2 September 2017

title

High-fat diet induces leptin resistance in leptin-deficient mice (English)

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2 September 2017

C E Koch

1

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2 September 2017

C Lowe

2

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2 September 2017

D Pretz

3

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2 September 2017

J Steger

4

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2 September 2017

L M Williams

5

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A Tups

6

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publication date

1 February 2014

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Journal of Neuroendocrinology

2 September 2017

published in

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2 September 2017

volume

26

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2 September 2017

issue

2

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2 September 2017

page(s)

58-67

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Positional cloning of the mouse obese gene and its human homologue

2 September 2017

cites work

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Making insulin-deficient type 1 diabetic rodents thrive without insulin

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Diet-induced obese mice develop peripheral, but not central, resistance to leptin

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Role of Signal Transducer and Activator of Transcription 3 in Regulation of Hypothalamic Proopiomelanocortin Gene Expression by Leptin

21 January 2018

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Region-specific leptin resistance within the hypothalamus of diet-induced obese mice.

21 January 2018

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Weight-reducing effects of the plasma protein encoded by the obese gene

21 January 2018

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21 January 2018

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Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

21 January 2018

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Leptin receptor gene expression and number in the brain are regulated by leptin level and nutritional status

21 January 2018

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HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and -independent mechanisms

21 January 2018

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Hyperleptinemia is required for the development of leptin resistance

21 January 2018

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Is obesity a disease of the blood-brain barrier? Physiological, pathological, and evolutionary considerations

21 January 2018

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Triglycerides induce leptin resistance at the blood-brain barrier

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TNF-alpha acts in the hypothalamus inhibiting food intake and increasing the respiratory quotient--effects on leptin and insulin signaling pathways

21 January 2018

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Reconstitution of IL6-inducible differentiation of a myeloid leukemia cell line by activated Stat factors

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Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity.

21 January 2018

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Outstanding Scientific Achievement Award Lecture 2010: deconstructing leptin: from signals to circuits

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Hypothalamic inflammation and energy homeostasis: resolving the paradox

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Acute inhibition of central c-Jun N-terminal kinase restores hypothalamic insulin signalling and alleviates glucose intolerance in diabetic mice

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Acute stimulation of glucose metabolism in mice by leptin treatment

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21 January 2018

Identifiers

DOI

10.1111/JNE.12131

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2 September 2017

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