βTrCP interacts with the ubiquitin-dependent endocytosis motif of the GH receptor in an unconventional manner (Q38316122)

2 September 2017

title

βTrCP interacts with the ubiquitin-dependent endocytosis motif of the GH receptor in an unconventional manner (English)

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2 September 2017

3

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2 September 2017

author name string

Ana C da Silva Almeida

1

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2 September 2017

Henry G Hocking

2

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2 September 2017

Ger J Strous

4

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2 September 2017

Agnes G S H van Rossum

5

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2 September 2017

language of work or name

English

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publication date

1 July 2013

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2 September 2017

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2 September 2017

volume

453

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2 September 2017

issue

2

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2 September 2017

page(s)

291-301

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Recent advances in growth hormone signaling

2 September 2017

cites work

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Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

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Growth hormone signalling and its regulation: preventing too much of a good thing

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Does growth hormone drive breast and other cancers?

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Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions

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Inflammatory cytokines and acquired growth hormone resistance

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Waste management - cytokines, growth factors and cachexia.

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The ubiquitin-proteasome pathway and the regulation of growth hormone receptor availability

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Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor.

21 January 2018

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The ubiquitin ligase SCF(betaTrCP) regulates the degradation of the growth hormone receptor

21 January 2018

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SCF and Cullin/Ring H2-based ubiquitin ligases

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Function and regulation of cullin-RING ubiquitin ligases

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SCFHOS ubiquitin ligase mediates the ligand-induced down-regulation of the interferon- receptor

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beta-Trcp mediates ubiquitination and degradation of the erythropoietin receptor and controls cell proliferation

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Negative regulation of prolactin receptor stability and signaling mediated by SCF(beta-TrCP) E3 ubiquitin ligase

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βTrCP controls GH receptor degradation via two different motifs

21 January 2018

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Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

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PIC: Protein Interactions Calculator

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The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

21 January 2018

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The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

21 January 2018

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Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis

21 January 2018

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Ubc13 and COOH terminus of Hsp70-interacting protein (CHIP) are required for growth hormone receptor endocytosis

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Molecular basis for class Ib anti-arrhythmic inhibition of cardiac sodium channels

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21 January 2018

Identifiers

DOI

10.1042/BJ20121843

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2 September 2017

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