A novel platinum compound inhibits constitutive Stat3 signaling and induces cell cycle arrest and apoptosis of malignant cells (Q38323134)

2 September 2017

A novel platinum compound inhibits constitutive Stat3 signaling and induces cell cycle arrest and apoptosis of malignant cells (English)

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2 September 2017

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James Turkson

1

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2 September 2017

Shumin Zhang

2

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2 September 2017

Linda B Mora

3

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2 September 2017

Audrey Burns

4

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2 September 2017

Said Sebti

5

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2 September 2017

Richard Jove

6

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2 September 2017

language of work or name

English

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publication date

26 July 2005

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Journal of Biological Chemistry

2 September 2017

10

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based on heuristic

inferred from page(s)

published in

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2 September 2017

280

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2 September 2017

32979-32988

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2 September 2017

38

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

2 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

STATs and gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

How cells respond to interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Control of myeloid differentiation and survival by Stats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Roles of STAT3 defined by tissue-specific gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Stat3 activation is required for cellular transformation by v-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Signal transducers and activators of transcription as regulators of growth, apoptosis and breast development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

STAT proteins: novel molecular targets for cancer drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

STAT signaling in head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

The role of STATs in myeloid differentiation and leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

STAT signaling in the pathogenesis and treatment of leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

The STATs of cancer--new molecular targets come of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

STAT proteins as novel targets for cancer drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Cisplatin induces a persistent activation of JNK that is related to cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Biomolecular targets for platinum antitumor drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Cisplatin: mode of cytotoxic action and molecular basis of resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Overexpressed pp60c-src can induce focus formation without complete transformation of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Dual effects of macrophage inflammatory protein-1alpha on osteolysis and tumor burden in the murine 5TGM1 model of myeloma bone disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

STAT3 participates in transcriptional activation of the C-reactive protein gene by interleukin-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Prolactin and interleukin-2 receptors in T lymphocytes signal through a MGF-STAT5-like transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

STAT3 regulates the growth and immunoglobulin production of BCL(1) B cell lymphoma through control of cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Transcription factors as targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Human serum albumin: spectroscopic studies of the paclitaxel binding and proximity relationships with cisplatin and adriamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Three-dimensional structure of the Stat3beta homodimer bound to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

Antitumor and cellular pharmacological properties of a novel platinum(IV) complex: trans-[PtCl(2)(OH)(2)(dimethylamine) (isopropylamine)].

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502694200

21 January 2018

Identifiers

DOI

10.1074/JBC.M502694200

1 reference

2 September 2017

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