Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1). (Q38326047)

2 September 2017

Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1). (English)

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2 September 2017

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5

G L Semenza

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P J van Diest

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2 September 2017

A E Greijer

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P van der Groep

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D Kemming

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A Shvarts

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G A Meijer

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M A van de Wiel

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J A M Belien

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E van der Wall

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1 July 2005

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Hypoxia facilitates tumour cell detachment by reducing expression of surface adhesion molecules and adhesion to extracellular matrices without loss of cell viability

2 September 2017

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https://api.crossref.org/works/10.1002%2FPATH.1778

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Tissue oxygen distribution in head and neck cancer patients

21 January 2018

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Hypoxia, clonal selection, and the role of HIF-1 in tumor progression

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF.

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Rac1 activity is required for the activation of hypoxia-inducible factor 1.

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Is HIF-1alpha a pro- or an anti-apoptotic protein?

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

A nuclear localization signal of human aryl hydrocarbon receptor nuclear translocator/hypoxia-inducible factor 1beta is a novel bipartite type recognized by the two components of nuclear pore-targeting complex

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Enhanced Motility in NIH 3T3 Fibroblasts That Overexpress Gelsolin

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12 October 2022

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Transcriptional response to hypoxia in human tumors

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Human U1 snRNP-specific C protein: complete cDNA and protein sequence and identification of a multigene family in mammals

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12 October 2022

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GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways

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https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Prognostic significance of tumor oxygenation in humans.

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

HIF-1α mRNA and protein upregulation involves Rho GTPase expression during hypoxia in renal cell carcinoma

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Hypoxic induction of prolyl 4-hydroxylase alpha (I) in cultured cells

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Modeling ischemia in vitro: selective depletion of adenine and guanine nucleotide pools

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Human gelsolin prevents apoptosis by inhibiting apoptotic mitochondrial changes via closing VDAC

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Hypoxia-inducible factor-1alpha is associated with angiogenesis, and expression of bFGF, PDGF-BB, and EGFR in invasive breast cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Levels of hypoxia-inducible factor-1 alpha during breast carcinogenesis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/PATH.1778

Identifiers

DOI

10.1002/PATH.1778

1 reference

2 September 2017

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