Hairpin coding end opening is mediated by RAG1 and RAG2 proteins (Q38329558)

2 September 2017

Hairpin coding end opening is mediated by RAG1 and RAG2 proteins (English)

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2 September 2017

Besmer E

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2 September 2017

Mansilla-Soto J

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2 September 2017

Cassard S

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2 September 2017

Sawchuk DJ

4

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2 September 2017

Brown G

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2 September 2017

Sadofsky M

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2 September 2017

Lewis SM

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2 September 2017

Nussenzweig MC

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2 September 2017

Cortes P

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2 September 2017

1 December 1998

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2 September 2017

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2 September 2017

2

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2 September 2017

6

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2 September 2017

817-828

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RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

2 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Mechanism of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

In vitro V(D)J recombination: signal joint formation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Analysis of regions of RAG-2 important for V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Initiation of V(D)J recombination in vitro obeying the 12/23 rule

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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Abnormal deletions in the T-cell receptor delta locus of mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Mice lacking TdT: mature animals with an immature lymphocyte repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Kinetic and structural analysis of a cleaved donor intermediate and a strand transfer intermediate in Tn10 transposition.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

A link between double-strand break-related repair and V(D)J recombination: the scid mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Hairpin opening by single-strand-specific nucleases

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Three lymphoid-specific factors account for all junctional diversity characteristic of somatic assembly of T-cell receptor and immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Tn10 transposition via a DNA hairpin intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Junctional sequences of T cell receptor gamma delta genes: implications for gamma delta T cell lineages and for a novel intermediate of V-(D)-J joining.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Increased frequency of N-region insertion in a murine pre-B-cell line infected with a terminal deoxynucleotidyl transferase retroviral expression vector

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Coding joint formation in a cell-free V(D)J recombination system

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

P nucleotide insertions and the resolution of hairpin DNA structures in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

The origins of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

RAG-1 and RAG-2-dependent assembly of functional complexes with V(D)J recombination substrates in solution

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

The mechanism of V(D)J recombination: a balance of diversity, specificity, and stability

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Identification of V(D)J recombination coding end intermediates in normal thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Chicken IgL gene rearrangement involves deletion of a circular episome and addition of single nonrandom nucleotides to both coding segments.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

P nucleotides in V(D)J recombination: a fine-structure analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Rejoining of DNA by the RAG1 and RAG2 proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

pEF-BOS, a powerful mammalian expression vector

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Polynucleotidyl transfer reactions in site-specific DNA recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Inversion of the phosphate chirality at the target site of Mu DNA strand transfer: Evidence for a one-step transesterification mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Nucleotide deletion and P addition in V(D)J recombination: a determinant role of the coding-end sequence

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Footprint analysis of the RAG protein recombination signal sequence complex for V(D)J type recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Production of high-titer helper-free retroviruses by transient transfection

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Formation and resolution of double-strand break intermediates in V(D)J rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Cell-free V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

A DNA end-binding factor involved in double-strand break repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Repair and Recombination: How to make ends meet

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Expression and V(D)J recombination activity of mutated RAG-1 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Definition of a core region of RAG-2 that is functional in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Sequences at the somatic recombination sites of immunoglobulin light-chain genes

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

The effect of Me2+ cofactors at the initial stages of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

V(D)J recombination: modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Structure of nonhairpin coding-end DNA breaks in cells undergoing V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

The end-joining reaction in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Localization, interaction, and RNA binding properties of the V(D)J recombination-activating proteins RAG1 and RAG2.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

The 12/23 rule is enforced at the cleavage step of V(D)J recombination in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

V(D)J recombination signal recognition: distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Impairment of V(D)J recombination in double-strand break repair mutants

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

New insights into V(D)J recombination and its role in the evolution of the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Somatic generation of antibody diversity

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Initiation of V(D)J recombination in a cell-free system.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Stimulation of V(D)J cleavage by high mobility group proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNa termini mediated by the viral integrase protein

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

From RAGs to stitches

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

V(D)J recombination: in vitro coding joint formation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980296-8

7 January 2021

10.1016/S1097-2765(00)80296-8

Identifiers

DOI

1 reference

2 September 2017

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