Substrate specificity and kinetic framework of a DNAzyme with an expanded chemical repertoire: a putative RNaseA mimic that catalyzes RNA hydrolysis independent of a divalent metal cation (Q38332536)

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English	Substrate specificity and kinetic framework of a DNAzyme with an expanded chemical repertoire: a putative RNaseA mimic that catalyzes RNA hydrolysis independent of a divalent metal cation	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

2 September 2017

Substrate specificity and kinetic framework of a DNAzyme with an expanded chemical repertoire: a putative RNaseA mimic that catalyzes RNA hydrolysis independent of a divalent metal cation (English)

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Europe PubMed Central

PMC publication ID

2 September 2017

author name string

Richard Ting

1

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Europe PubMed Central

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2 September 2017

Jason M Thomas

2

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2 September 2017

Leonard Lermer

3

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2 September 2017

David M Perrin

4

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2 September 2017

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publication date

29 December 2004

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2 September 2017

Nucleic Acids Research

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2 September 2017

32

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Europe PubMed Central

PMC publication ID

2 September 2017

22

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Europe PubMed Central

PMC publication ID

2 September 2017

6660-6672

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Europe PubMed Central

PMC publication ID

2 September 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC545449/fullTextXML

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Quantitative analysis of a RNA-cleaving DNA catalyst obtained via in vitro selection

1 reference

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Synthetic metallonucleases for RNA cleavage

1 reference

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Kinetic and thermodynamic characterization of the RNA-cleaving 8-17 deoxyribozyme

1 reference

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Exceptionally fast self-cleavage by a Neurospora Varkud satellite ribozyme

1 reference

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Aminomodified nucleobases: functionalized nucleoside triphosphates applicable for SELEX.

1 reference

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6 September 2017

Structural rearrangements of the 10-23 DNAzyme to beta 3 integrin subunit mRNA induced by cations and their relations to the catalytic activity

1 reference

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Incorporation of 8-histaminyl-deoxyadenosine [8-(2-(4-imidazolyl)ethylamino)-2'-deoxyriboadenosine] into oligodeoxyribonucleotides by solid phase phosphoramidite coupling

1 reference

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1 reference

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1 reference

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A new and efficient DNA enzyme for the sequence-specific cleavage of RNA.

1 reference

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RNA cleavage by a DNA enzyme with extended chemical functionality

1 reference

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Bridging the gap between proteins and nucleic acids: a metal-independent RNAseA mimic with two protein-like functionalities

1 reference

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6 September 2017

The hammerhead cleavage reaction in monovalent cations

1 reference

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6 September 2017

Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations.

1 reference

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Enhancing the catalytic repertoire of nucleic acids. II. Simultaneous incorporation of amino and imidazolyl functionalities by two modified triphosphates during PCR.

1 reference

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In vitro selection of a ligase ribozyme carrying alkylamino groups in the side chains

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Kinetic scheme for intermolecular RNA cleavage by a ribozyme derived from hepatitis delta virus RNA.

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Functionalized nucleoside 5'-triphosphates for in vitro selection of new catalytic ribonucleic acids

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Relationship between internucleotide linkage geometry and the stability of RNA.

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Expanding the catalytic repertoire of nucleic acid catalysts: simultaneous incorporation of two modified deoxyribonucleoside triphosphates bearing ammonium and imidazolyl functionalities

1 reference

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6 September 2017

The hammerhead, hairpin and VS ribozymes are catalytically proficient in monovalent cations alone

1 reference

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Mechanism and utility of an RNA-cleaving DNA enzyme

1 reference

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An amino acid as a cofactor for a catalytic polynucleotide

1 reference

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Free magnesium-ion concentration in erythrocytes by 31P NMR: the effect of metabolite-haemoglobin interactions

1 reference

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A DNA enzyme with Mg(2+)-dependent RNA phosphoesterase activity

1 reference

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A DNA enzyme that cleaves RNA

1 reference

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Selection of RNA amide synthases

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Evidence for the metal-cofactor independence of an RNA phosphodiester-cleaving DNA enzyme

1 reference

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Characterization and divalent metal-ion dependence of in vitro selected deoxyribozymes which cleave DNA/RNA chimeric oligonucleotides

1 reference

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A general purpose RNA-cleaving DNA enzyme

1 reference

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A kinetic and thermodynamic framework for the hammerhead ribozyme reaction

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Efficient trans-cleavage of a stem-loop RNA substrate by a ribozyme derived from neurospora VS RNA

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Monitoring cytosolic free magnesium in cultured chicken heart cells by use of the fluorescent indicator Furaptra

1 reference

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Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site

1 reference

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1 reference

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1 reference

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Hairpin ribozyme cleavage catalyzed by aminoglycoside antibiotics and the polyamine spermine in the absence of metal ions

1 reference

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Metal ions play a passive role in the hairpin ribozyme catalysed reaction

1 reference

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1 reference

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Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities

1 reference

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1 reference

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Studies on Some Interactions and Reactions of Oligonucleotides in Aqueous Solution*

1 reference

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Cytosolic free magnesium levels in ischemic rat heart

1 reference

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A conformational switch controls hepatitis delta virus ribozyme catalysis

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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12 December 2020

based on heuristic

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Redesigning nucleic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/15625232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inorganic Mimics of Ribonucleases and Ribozymes: From Random Cleavage to Sequence-Specific Chemistry to Catalytic Antisense Drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15625232

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inferred from PubMed ID database lookup

Toward an RNaseA mimic: A DNAzyme with imidazoles and cationic amines

1 reference

https://pubmed.ncbi.nlm.nih.gov/15625232

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inferred from PubMed ID database lookup

Functionalized DNA: A New Replicable Biopolymer We thank Dr. Andreas Marx, University of Bonn, for helpful advice and discussions. This work was supported by the Fonds der Chemischen Industrie, the Karl-Ziegler Stiftung, and the Deutsche Forschungsg

1 reference

https://pubmed.ncbi.nlm.nih.gov/15625232

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based on heuristic

inferred from PubMed ID database lookup

Kinetics of intermolecular cleavage by hammerhead ribozymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15625232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of ribozyme binding of substrate revealed by fluorescence-detected stopped-flow methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/15625232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expanding the Potential of DNA for Binding and Catalysis: Highly Functionalized dUTP Derivatives That Are Substrates for Thermostable DNA Polymerases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15625232

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A kinetic mechanism for cleavage of precursor tRNA(Asp) catalyzed by the RNA component of Bacillus subtilis ribonuclease P

1 reference

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inferred from PubMed ID database lookup

Building a kinetic framework for group II intron ribozyme activity: quantitation of interdomain binding and reaction rate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15625232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic mechanism of the hairpin ribozyme. Identification and characterization of two nonexchangeable conformations

1 reference

https://pubmed.ncbi.nlm.nih.gov/15625232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A unique mechanism for RNA catalysis: the role of metal cofactors in hairpin ribozyme cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/15625232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An unusual pH-independent and metal-ion-independent mechanism for hairpin ribozyme catalysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15625232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNA-catalysed carbon–carbon bond formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15625232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/GKH1007

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 September 2017

ResearchGate publication ID

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