ERK kinase inhibition stabilizes the aryl hydrocarbon receptor: implications for transcriptional activation and protein degradation (Q38333688)

2 September 2017

ERK kinase inhibition stabilizes the aryl hydrocarbon receptor: implications for transcriptional activation and protein degradation (English)

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2 September 2017

Shujuan Chen

1

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2 September 2017

Theresa Operaña

2

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2 September 2017

Jessica Bonzo

3

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2 September 2017

Nghia Nguyen

4

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2 September 2017

Robert H Tukey

5

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2 September 2017

language of work or name

English

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publication date

29 November 2004

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Journal of Biological Chemistry

2 September 2017

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2 September 2017

280

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2 September 2017

6

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2 September 2017

4350-4359

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The hsp90 chaperone complex regulates intracellular localization of the dioxin receptor

2 September 2017

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ARA9 modifies agonist signaling through an increase in cytosolic aryl hydrocarbon receptor

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Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo

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Resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity and abnormal liver development in mice carrying a mutation in the nuclear localization sequence of the aryl hydrocarbon receptor.

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Nuclear localization and export signals of the human aryl hydrocarbon receptor

21 January 2018

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Developing toxicologically predictive gene sets using cDNA microarrays and Bayesian classification.

21 January 2018

1 reference

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Identification of transactivation and repression functions of the dioxin receptor and its basic helix-loop-helix/PAS partner factor Arnt: inducible versus constitutive modes of regulation

21 January 2018

1 reference

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Protein kinase C modulates regulation of the CYP1A1 gene by the aryl hydrocarbon receptor

21 January 2018

1 reference

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The mechanism of AH receptor protein down-regulation (degradation) and its impact on AH receptor-mediated gene regulation

21 January 2018

1 reference

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Degradation of the basic helix-loop-helix/Per-ARNT-Sim homology domain dioxin receptor via the ubiquitin/proteasome pathway

21 January 2018

1 reference

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2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway: role of the transcription activaton and DNA binding of AhR

21 January 2018

1 reference

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Activation of mitogen-activated protein kinases (MAPKs) by aromatic hydrocarbons: role in the regulation of aryl hydrocarbon receptor (AHR) function

21 January 2018

1 reference

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Suppression of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated CYP1A1 and CYP1B1 induction by 12-O-tetradecanoylphorbol-13-acetate: role of transforming growth factor beta and mitogen-activated protein kinases

21 January 2018

1 reference

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The aryl hydrocarbon receptor antagonist, 3'methoxy-4'nitroflavone, attenuates 2,3,7,8-tetrachlorodibenzo-p-dioxin-dependent regulation of growth factor signaling and apoptosis in the MCF-10A cell line.

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A synthetic inhibitor of the mitogen-activated protein kinase cascade

21 January 2018

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Identification of a novel inhibitor of mitogen-activated protein kinase kinase

21 January 2018

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Suppression by p38 MAP kinase inhibitors (pyridinyl imidazole compounds) of Ah receptor target gene activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin and the possible mechanism

21 January 2018

1 reference

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The Jun N-terminal kinase inhibitor SP600125 is a ligand and antagonist of the aryl hydrocarbon receptor

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Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context

21 January 2018

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The role of the Ah receptor and p38 in benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced apoptosis.

21 January 2018

1 reference

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Activation of the Ah receptor signaling pathway by prostaglandins

21 January 2018

1 reference

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ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

21 January 2018

1 reference

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Aromatic hydrocarbon receptor-driven Bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals

21 January 2018

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Aryl hydrocarbon receptor activation and cytochrome P450 1A induction by the mitogen-activated protein kinase inhibitor U0126 in hepatocytes

21 January 2018

1 reference

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Different structural requirements of the ligand binding domain of the aryl hydrocarbon receptor for high- and low-affinity ligand binding and receptor activation

21 January 2018

1 reference

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Phosphorylation of nuclear localization signal inhibits the ligand-dependent nuclear import of aryl hydrocarbon receptor

21 January 2018

1 reference

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Prolonged depletion of AH receptor without alteration of receptor mRNA levels after treatment of cells in culture with 2,3,7,8-tetrachlorodibenzo-p-dioxin

21 January 2018

1 reference

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Proteasome inhibition induces nuclear translocation and transcriptional activation of the dioxin receptor in mouse embryo primary fibroblasts in the absence of xenobiotics

21 January 2018

1 reference

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Aryl hydrocarbon receptor imported into the nucleus following ligand binding is rapidly degraded via the cytosplasmic proteasome following nuclear export

21 January 2018

1 reference

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Superinduction of CYP1A1 gene expression. Regulation of 2,3,7,8- tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximide

21 January 2018

1 reference

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Functional analysis of murine aryl hydrocarbon (AH) receptors defective in nuclear import: impact on AH receptor degradation and gene regulation

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M411554200

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2 September 2017

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