The transcription factor Pax6 regulates survival of dopaminergic olfactory bulb neurons via crystallin αA. (Q38339204)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21092858%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

The transcription factor Pax6 regulates survival of dopaminergic olfactory bulb neurons via crystallin αA (English)

1 reference

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16 January 2020

1 reference

1 reference

2

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16 January 2020

Michael A Rieger

6

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16 January 2020

Timm Schroeder

7

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16 January 2020

10

Magdalena Götz

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16 January 2020

author name string

Jovica Ninkovic

1

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16 January 2020

Stefania Petricca

3

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16 January 2020

Alexandra Lepier

4

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16 January 2020

Jian Sun

5

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16 January 2020

Jack Favor

9

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16 January 2020

Ales Cvekl

8

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16 January 2020

language of work or name

English

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publication date

1 November 2010

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16 January 2020

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16 January 2020

volume

68

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16 January 2020

issue

4

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16 January 2020

page(s)

682-694

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describes a project that uses

16 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4388427/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Native chromatin preparation and Illumina/Solexa library construction

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Adult generation of glutamatergic olfactory bulb interneurons.

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Identification of pax6-dependent gene regulatory networks in the mouse lens

6 September 2017

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Trim11 modulates the function of neurogenic transcription factor Pax6 through ubiquitin-proteosome system

6 September 2017

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Relationship of Pax6 activity levels to the extent of eye development in the mouse, Mus musculus

6 September 2017

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A dlx2- and pax6-dependent transcriptional code for periglomerular neuron specification in the adult olfactory bulb

6 September 2017

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Concise review: Pax6 transcription factor contributes to both embryonic and adult neurogenesis as a multifunctional regulator

6 September 2017

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Control of apoptosis by asymmetric cell division

6 September 2017

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Mechanisms and functional implications of adult neurogenesis

6 September 2017

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Heat shock proteins: essential proteins for apoptosis regulation

6 September 2017

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Mechanism of small heat shock protein function in vivo: a knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell death

6 September 2017

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Transcriptional regulation of mesencephalic dopaminergic neurons: the full circle of life and death.

6 September 2017

1 reference

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Dynamic contribution of nestin-expressing stem cells to adult neurogenesis

6 September 2017

1 reference

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Distinct modes of neuron addition in adult mouse neurogenesis.

6 September 2017

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Genetic and epigenetic mechanisms of gene regulation during lens development

6 September 2017

1 reference

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Up-regulation of tau, a brain microtubule-associated protein, in lens cortical fractions of aged alphaA-, alphaB-, and alphaA/B-crystallin knockout mice

6 September 2017

1 reference

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Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease

6 September 2017

1 reference

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Chromatin immunoprecipitation and microarray-based analysis of protein location

6 September 2017

1 reference

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Crystallins in the eye: Function and pathology

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Loss- and gain-of-function analyses reveal targets of Pax6 in the developing mouse telencephalon.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

alphaB-crystallin competes with Alzheimer's disease beta-amyloid peptide for peptide-peptide interactions and induces oxidation of Abeta-Met35

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Regulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Caspase-dependent secondary lens fiber cell disintegration in alphaA-/alphaB-crystallin double-knockout mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Pax6 is required for making specific subpopulations of granule and periglomerular neurons in the olfactory bulb.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Ventralized dorsal telencephalic progenitors in Pax6 mutant mice generate GABA interneurons of a lateral ganglionic eminence fate.

6 September 2017

1 reference

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Molecular dissection of Pax6 function: the specific roles of the paired domain and homeodomain in brain development

6 September 2017

1 reference

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Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome.

6 September 2017

1 reference

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Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis

6 September 2017

1 reference

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Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference

6 September 2017

1 reference

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Apoptosis and caspases in neurodegenerative diseases

6 September 2017

1 reference

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Cyclosporin A inhibits caspase-independent death of NGF-deprived sympathetic neurons: a potential role for mitochondrial permeability transition

6 September 2017

1 reference

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Glial cells generate neurons: the role of the transcription factor Pax6.

6 September 2017

1 reference

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Molecular mechanisms underlying cell fate specification in the developing telencephalon

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Identification of genes downstream of Pax6 in the mouse lens using cDNA microarrays

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Molecular characterization of Pax6(2Neu) through Pax6(10Neu): an extension of the Pax6 allelic series and the identification of two possible hypomorph alleles in the mouse Mus musculus.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Gsh2 and Pax6 play complementary roles in dorsoventral patterning of the mammalian telencephalon

6 September 2017

1 reference

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Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision

6 September 2017

1 reference

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Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Pax6 modulates the dorsoventral patterning of the mammalian telencephalon

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Expression of betaB(2)-crystallin mRNA and protein in retina, brain, and testis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Discrimination between apoptosis and necrosis of neurons under oxidative stress.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus

6 September 2017

1 reference

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Long-distance neuronal migration in the adult mammalian brain

6 September 2017

1 reference

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Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing

6 September 2017

1 reference

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A complex array of positive and negative elements regulates the chicken alpha A-crystallin gene: involvement of Pax-6, USF, CREB and/or CREM, and AP-1 proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

6 September 2017

1 reference

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Neuronal loss in the pedunculopontine tegmental nucleus in Parkinson disease and in progressive supranuclear palsy

6 September 2017

1 reference

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Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene

6 September 2017

1 reference

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Continuous single-cell imaging of blood generation from haemogenic endothelium.

6 September 2017

1 reference

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Neurotrophin receptor-mediated death of misspecified neurons generated from embryonic stem cells lacking Pax6.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Neuronal fate determinants of adult olfactory bulb neurogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Par-complex proteins promote proliferative progenitor divisions in the developing mouse cerebral cortex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Three novel Pax6 alleles in the mouse leading to the same small-eye phenotype caused by different consequences at target promoters

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Pax6 controls radial glia differentiation in the cerebral cortex

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Neurons derived from P19 embryonal carcinoma cells have varied morphologies and neurotransmitters.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Possible coexistence of amino acid (gamma-aminobutyric acid), amine (dopamine) and peptide (substance P); neurons containing immunoreactivities for glutamic acid decarboxylase, tyrosine hydroxylase and substance P in the hamster main olfactory bulb

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

alpha B-crystallin is present in reactive glia in Creutzfeldt-Jakob disease

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Role of sensory activity on chemospecific populations of interneurons in the adult olfactory bulb.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Elevated P75NTR expression causes death of engrailed-deficient midbrain dopaminergic neurons by Erk1/2 suppression.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Novel allele of crybb2 in the mouse and its expression in the brain.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Chemical properties of type 1 and type 2 periglomerular cells in the mouse olfactory bulb are different from those in the rat olfactory bulb

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Higher nigrostriatal dopamine neuron loss in early than late onset Parkinson's disease?--a [99mTc]-TRODAT-1 SPECT study

31 August 2018

1 reference

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Postnatal changes of vesicular glutamate transporter (VGluT)1 and VGluT2 immunoreactivities and their colocalization in the mouse forebrain

31 August 2018

1 reference

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Targeted gene expression in dopamine and serotonin neurons of the mouse brain

31 August 2018

1 reference

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Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: effects on amyloid fibril formation and chaperone activity

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Heterozygous PAX6 mutation, adult brain structure and fronto-striato-thalamic function in a human family

31 August 2018

1 reference

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Maturation and death of adult-born olfactory bulb granule neurons: role of olfaction.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Pax6 is required to regulate the cell cycle and the rate of progression from symmetrical to asymmetrical division in mammalian cortical progenitors.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for Pax6 and Gsh2.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Dopamine transporter immunohistochemistry in median eminence, amygdala, and other areas of the rat brain

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

Roles of Pax-genes in developing and adult brain as suggested by expression patterns.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388427

10.1016/J.NEURON.2010.09.030

31 August 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21092858%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21092858%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

21092858

1 reference