Suppression of transcription factor PDX-1/IPF1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells. (Q38342794)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9312185%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Suppression of transcription factor PDX-1/IPF1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells (English)

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6 November 2019

2

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6 November 2019

Jun-ichi Miyazaki

6

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6 November 2019

author name string

Kajimoto Y

1

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6 November 2019

Matsuoka T

3

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6 November 2019

Kaneto H

4

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6 November 2019

Fujitani Y

5

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6 November 2019

Yamasaki Y

7

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6 November 2019

language of work or name

English

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publication date

1 October 1997

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Journal of Clinical Investigation

6 November 2019

published in

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6 November 2019

volume

100

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6 November 2019

issue

7

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6 November 2019

page(s)

1840-1846

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Differentiation of glucose toxicity from beta cell exhaustion during the evolution of defective insulin gene expression in the pancreatic islet cell line, HIT-T15

6 November 2019

cites work

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Involvement of the homeodomain-containing transcription factor PDX-1 in islet amyloid polypeptide gene transcription

6 September 2017

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Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1

6 September 2017

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Chronic exposure of betaTC-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator

6 September 2017

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Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters

6 September 2017

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Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein.

6 September 2017

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Insulin-promoter-factor 1 is required for pancreas development in mice

6 September 2017

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IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene

6 September 2017

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Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor

6 September 2017

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Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein

6 September 2017

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Absence of radius and ulna in mice lacking hoxa-11 andhoxd-11

6 September 2017

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Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression

6 September 2017

1 reference

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Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells

6 September 2017

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A beta-cell-specific protein binds to the two major regulatory sequences of the insulin gene enhancer

6 September 2017

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The amino acid sequence of rat liver glucokinase deduced from cloned cDNA.

6 September 2017

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Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone

6 September 2017

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Banting lecture 1990. Beta-cells in type II diabetes mellitus

6 September 2017

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Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations

6 September 2017

1 reference

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Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells

6 September 2017

1 reference

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IPF1, a homeodomain-containing transactivator of the insulin gene

14 September 2017

1 reference

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Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta-cell function

27 September 2017

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The human glucokinase gene beta-cell-type promoter: an essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells

27 September 2017

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The reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to high glucose concentration is associated with the loss of RIPE3b1 and STF-1 transcription factor expression

27 September 2017

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Cell-free activation of a DNA-binding protein by epidermal growth factor

27 September 2017

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The insulin gene promoter. A simplified nomenclature

23 June 2018

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Insulin secretion and cAMP metabolism in HIT cells. Reciprocal and serial passage-dependent relationships

23 June 2018

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Positive and negative regulation of the human insulin gene by multiple trans-acting factors

23 June 2018

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Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

23 June 2018

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Comparison of cytokine effects on mouse pancreatic alpha-cell and beta-cell lines. Viability, secretory function, and MHC antigen expression

23 June 2018

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23 June 2018

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Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny.

31 August 2018

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The Pan basic helix-loop-helix proteins are required for insulin gene expression

31 August 2018

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The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL/KsJ and C57BL/6J strains

31 August 2018

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12 December 2020

Reduced Insulin, GLUT2, and IDX-1 in -Cells After Partial Pancreatectomy

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12 December 2020

The role of Hox genes in limb development

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12 December 2020

Evolution of β-Cell Dysfunction in the Male Zucker Diabetic Fatty Rat

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12 December 2020

PDX-1 induces insulin and glucokinase gene expressions in alphaTC1 clone 6 cells in the presence of betacellulin

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12 December 2020

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability

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12 December 2020

Identifiers

DOI

10.1172/JCI119712

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9312185%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9312185%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

9312185

1 reference