Lipopolysaccharide challenge: immunological effects and safety in humans (Q38345644)

2 September 2017

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title

Lipopolysaccharide challenge: immunological effects and safety in humans (English)

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2 September 2017

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Stefan Zielen

1

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2 September 2017

Jordis Trischler

series ordinal

2

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2 September 2017

Ralf Schubert

series ordinal

3

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2 September 2017

publication date

6 February 2015

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Expert Review of Clinical Immunology

2 September 2017

published in

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2 September 2017

volume

11

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2 September 2017

issue

3

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2 September 2017

page(s)

409-418

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Airborne allergens, endotoxins, and particulate matter in elementary schools, results from Germany (LUPE 2).

2 September 2017

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From therapy to experimental model: a hundred years of endotoxin administration to human subjects

21 January 2018

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EFFECTS PRODUCED BY THE INTRAVENOUS INJECTION IN MAN OF A TOXIC ANTIGENIC MATERIAL DERIVED FROM EBERTHELLA TYPHOSA: CLINICAL, HEMATOLOGICAL, CHEMICAL AND SEROLOGICAL STUDIES.

21 January 2018

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MECHANISMS OF ENDOTOXIN TOLERANCE. II. RELATIONSHIP BETWEEN ENDOTOXIN TOLERANCE AND RETICULOENDOTHELIAL SYSTEM PHAGOCYTIC ACTIVITY IN MAN

21 January 2018

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Human endotoxemia: a model for mechanistic insight and therapeutic targeting

21 January 2018

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Epinephrine exerts anticoagulant effects during human endotoxemia

21 January 2018

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Dose-response relationship to inhaled endotoxin in normal subjects

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Blood inflammatory response to inhaled endotoxin in normal subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Inflammatory response after inhalation of bacterial endotoxin assessed by the induced sputum technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Does the shape of lipid A determine the interaction of LPS with Toll-like receptors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

LPS inhalation challenge: a new tool to characterize the inflammatory response in humans.

21 January 2018

1 reference

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Lipopolysaccharide challenge of humans as a model for chronic obstructive lung disease exacerbations

21 January 2018

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A randomized controlled trial of peripheral blood mononuclear cell depletion in experimental human lung inflammation.

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Influence of fluticasone and salmeterol on airway effects of inhaled organic dust;an in vivo and ex vivo study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Fluticasone and ibuprofen do not add to the effect of salmeterol on organic dust-induced airway inflammation and bronchial hyper-responsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Methacholine challenge--comparison of an ATS protocol to a new rapid single concentration technique.

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Inhaled endotoxin and decreased spirometric values. An exposure-response relation for cotton dust

21 January 2018

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Health effects due to endotoxin inhalation (review).

21 January 2018

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Longitudinal changes in pulmonary function and respiratory symptoms in cotton textile workers: a 15-yr follow-up study

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Exposure assessment and lung function in pig and poultry farmers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Natural history and risk factors of early respiratory responses to exposure to cotton dust in newly exposed workers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Differential inflammatory response to inhaled lipopolysaccharide targeted either to the airways or the alveoli in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Environmental context differentially affects behavioral, leukocyte, cortisol, and interleukin-6 responses to low doses of endotoxin in the rhesus monkey

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Inhalation toxicology models of endotoxin- and bioaerosol-induced inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Pharmacokinetics of inhaled drugs

21 January 2018

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https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Inhaled endotoxin in healthy human subjects: a dose-related study on systemic effects and peripheral CD4+ and CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Effect of inhaled endotoxin on induced sputum in normal, atopic, and atopic asthmatic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Inflammatory response to acute inhalation of endotoxin in asthmatic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Healthy subjects express differences in clinical responses to inhaled lipopolysaccharide that are related with inflammation and with atopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Local inflammatory responses following bronchial endotoxin instillation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Time course of endotoxin-induced airways' inflammation in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Inhaled LPS induces blood release of Clara cell specific protein (CC16) in human beings.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Toll-like receptor 4 variants reduce airway response in human subjects at high endotoxin levels in a swine facility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

LPS binding protein is important in the airway response to inhaled endotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Antiinflammatory effects of salmeterol after inhalation of lipopolysaccharide by healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Atopic asthmatic patients have reduced airway inflammatory cell recruitment after inhaled endotoxin challenge compared with healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Increased expression of p38 MAPK in human bronchial epithelium after lipopolysaccharide exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Increase in proinflammatory cytokines in peripheral blood without haemostatic changes after LPS inhalation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Inhaled LPS challenges in smokers: a study of pulmonary and systemic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Inhibition of LPS-induced airway neutrophilic inflammation in healthy volunteers with an oral CXCR2 antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

Low-dose endotoxin inhalation in healthy volunteers--a challenge model for early clinical drug development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.2015.1012158

10.1586/1744666X.2015.1012158

21 January 2018

Identifiers

DOI

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2 September 2017

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