Extending the functions of the homeotic transcription factor Cdx2 in the digestive system through nontranscriptional activities. (Q38348766)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25663763%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

review article

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title

Extending the functions of the homeotic transcription factor Cdx2 in the digestive system through nontranscriptional activities (English)

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29 February 2020

1

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29 February 2020

Isabelle Duluc

2

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29 February 2020

author name string

Jean-Marie Reimund

3

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29 February 2020

Isabelle Gross

4

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29 February 2020

Claire Domon-Dell

5

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29 February 2020

language of work or name

English

0 references

publication date

1 February 2015

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25663763%20AND%20SRC:MED&resulttype=core&format=json

World Journal of Gastroenterology

29 February 2020

published in

1 reference

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29 February 2020

volume

21

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29 February 2020

issue

5

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29 February 2020

page(s)

1436-1443

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Transcriptional regulation of the intestinal nuclear bile acid farnesoid X receptor (FXR) by the caudal-related homeobox 2 (CDX2).

29 February 2020

cites work

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Transcription-independent p53 apoptosis: an alternative route to death

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The intestine-specific transcription factor Cdx2 inhibits beta-catenin/TCF transcriptional activity by disrupting the beta-catenin-TCF protein complex

6 September 2017

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Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer.

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6 September 2017

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Transcription-independent functions of MYC: regulation of translation and DNA replication

6 September 2017

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Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo

6 September 2017

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The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis

6 September 2017

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The genesis and evolution of homeobox gene clusters

6 September 2017

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Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation

6 September 2017

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Cdx2 is essential for axial elongation in mouse development

6 September 2017

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Identifying target genes regulated downstream of Cdx2 by microarray analysis

6 September 2017

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Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice

6 September 2017

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Cdx2 protein expression in normal and malignant human tissues: an immunohistochemical survey using tissue microarrays

6 September 2017

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The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development.

6 September 2017

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CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia.

6 September 2017

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Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation

6 September 2017

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Cloning of the human claudin-2 5'-flanking region revealed a TATA-less promoter with conserved binding sites in mouse and human for caudal-related homeodomain proteins and hepatocyte nuclear factor-1alpha

6 September 2017

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Phosphorylation of the serine 60 residue within the Cdx2 activation domain mediates its transactivation capacity

6 September 2017

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6 September 2017

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Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation

6 September 2017

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Activation of enhancer elements by the homeobox gene Cdx2 is cell line specific

6 September 2017

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Regulation of lactase-phlorizin hydrolase gene expression by the caudal-related homoeodomain protein Cdx-2

6 September 2017

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Homeosis and intestinal tumours in Cdx2 mutant mice

6 September 2017

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Expression of Cdx-2 in the mouse embryo and placenta: possible role in patterning of the extra-embryonic membranes

6 September 2017

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Activation of proglucagon gene transcription through a novel promoter element by the caudal-related homeodomain protein cdx-2/3.

6 September 2017

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A homeodomain protein related to caudal regulates intestine-specific gene transcription

6 September 2017

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Isolation and characterization of target sequences of the chicken CdxA homeobox gene

6 September 2017

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Homeobox gene expression in the intestinal epithelium of adult mice

6 September 2017

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Novel DNA-binding proteins regulate intestine-specific transcription of the sucrase-isomaltase gene

6 September 2017

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Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex

6 September 2017

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Expression and localisation of insulin receptor substrate 2 in normal intestine and colorectal tumours. Regulation by intestine-specific transcription factor CDX2.

6 September 2017

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The homeobox gene CDX2 is aberrantly expressed and associated with an inferior prognosis in patients with acute lymphoblastic leukemia

14 September 2017

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Multiple regulatory regions control the complex expression pattern of the mouse Cdx2 homeobox gene

14 September 2017

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Homeobox protein CDX2 reduces Cox-2 transcription by inactivating the DNA-binding capacity of nuclear factor-kappaB.

14 September 2017

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14 September 2017

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CDX2-regulated expression of iron transport protein hephaestin in intestinal and colonic epithelium

14 September 2017

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Homeodomain protein CDX2 regulates COX-2 expression in colorectal cancer.

14 September 2017

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Human MUC2 mucin gene is transcriptionally regulated by Cdx homeodomain proteins in gastrointestinal carcinoma cell lines.

14 September 2017

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Intestinal epithelial cell differentiation involves activation of p38 mitogen-activated protein kinase that regulates the homeobox transcription factor CDX2.

14 September 2017

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Cdx1 and cdx2 expression during intestinal development

27 September 2017

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Cdx2 regulates patterning of the intestinal epithelium.

27 September 2017

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The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells

23 June 2018

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CDX2 expression in the intestinal-type gastric epithelial neoplasia: frequency and significance.

23 June 2018

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Expression of osteopontin and CDX2: indications of phenotypes and prognosis in advanced gastric cancer.

31 August 2018

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Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation.

31 August 2018

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Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression

31 August 2018

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CDX2, a homeobox transcription factor, upregulates transcription of the p21/WAF1/CIP1 gene

31 August 2018

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Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice

31 August 2018

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Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells.

31 August 2018

1 reference

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Non-transcriptional interactions of Hox proteins: inventory, facts, and future directions

31 August 2018

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Crossref

https://api.crossref.org/works/10.3748%2FWJG.V21.I5.1436

Regulation of the gene encoding the intestinal bile acid transporter ASBT by the caudal-type homeobox proteins CDX1 and CDX2

21 January 2018

1 reference

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CDX2 in congenital gut gastric-type heteroplasia and intestinal-type Meckel diverticula

1 October 2018

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Suppression of colonic polyposis by homeoprotein CDX2 through its nontranscriptional function that stabilizes p27Kip1

1 October 2018

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12 December 2020

Characteristics of the binding of aminoglycoside antibiotics to teichoic acids. A potential model system for interaction of aminoglycosides with polyanions

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12 December 2020

CDX2 expression in the stomach with intestinal metaplasia and intestinal-type cancer: Prognostic implications

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12 December 2020

Conversion of gastric mucosa to intestinal metaplasia in Cdx2-expressing transgenic mice

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12 December 2020

Expression of Cdx2 and claudin-2 in the multistage tissue of gastric carcinogenesis

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12 December 2020

Identifiers

DOI

10.3748/WJG.V21.I5.1436

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25663763%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25663763%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

25663763

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25663763%20AND%20SRC:MED&resulttype=core&format=json