Microtubular interactions of presenilin direct kinesis of Aβ peptide and its precursors (Q38354810)

2 September 2017

Microtubular interactions of presenilin direct kinesis of Abeta peptide and its precursors (English)

1 reference

2 September 2017

Microtubular interactions of presenilin direct kinesis of Aβ peptide and its precursors (English)

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

31 December 2023

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

31 December 2023

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

31 December 2023

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

31 December 2023

author name string

Nikolaos Tezapsidis

1

1 reference

2 September 2017

George Merz

3

1 reference

2 September 2017

Heni Hong

4

1 reference

2 September 2017

Patricia A. Merz

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12738804

31 December 2023

language of work or name

English

0 references

publication date

8 May 2003

1 reference

full work available at URL

2 September 2017

http://www.fasebj.org/cgi/content/abstract/17/10/1322

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12738804

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.02-0980fje

31 December 2023

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

https://onlinelibrary.wiley.com/doi/full-xml/10.1096/fj.02-0980fje

31 December 2023

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

31 December 2023

1 reference

2 September 2017

17

1 reference

2 September 2017

10

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2 September 2017

1322-1324

1 reference

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

2 September 2017

1

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch

31 December 2023

2

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions

31 December 2023

3

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Aph-2/Nicastrin: an essential component of gamma-secretase and regulator of Notch signaling and Presenilin localization

31 December 2023

5

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex

31 December 2023

6

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Binding partners of Alzheimer's disease proteins: are they physiologically relevant?

31 December 2023

7

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

31 December 2023

8

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch

31 December 2023

9

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Endogenous beta-amyloid production in presenilin-deficient embryonic mouse fibroblasts

31 December 2023

10

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Altered binding of mutated presenilin with cytoskeleton-interacting proteins

31 December 2023

11

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Secretion and accumulation of Alzheimer's beta-protein by cultured vascular smooth muscle cells from old and young dogs.

31 December 2023

12

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Release of nontransmembrane full-length Alzheimer's amyloid precursor protein from the lumenar surface of chromaffin granule membranes

31 December 2023

14

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Cholinergic agonists stimulate secretion of soluble full-length amyloid precursor protein in neuroendocrine cells

31 December 2023

15

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Full-length and truncated Alzheimer amyloid precursors in chromaffin granules: solubilization of membrane amyloid precursor is mediated by an enzymatic mechanism.

31 December 2023

16

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Distinct secretases, a cysteine protease and a serine protease, generate the C termini of amyloid beta-proteins Abeta1-40 and Abeta1-42, respectively

31 December 2023

17

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

DNA sequencing with chain-terminating inhibitors

31 December 2023

18

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs).

31 December 2023

19

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.

31 December 2023

20

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

The aspartate-257 of presenilin 1 is indispensable for mouse development and production of beta-amyloid peptides through beta-catenin-independent mechanisms

31 December 2023

21

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

The nonconserved hydrophilic loop domain of presenilin (PS) is not required for PS endoproteolysis or enhanced abeta 42 production mediated by familial early onset Alzheimer's disease-linked PS variants.

31 December 2023

22

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method

31 December 2023

23

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPases.

31 December 2023

25

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Calcium ionophore increases amyloid beta peptide production by cultured cells

31 December 2023

26

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner

31 December 2023

27

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

CLIP-170 links endocytic vesicles to microtubules

31 December 2023

28

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I

31 December 2023

29

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations

31 December 2023

30

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Neuronal apoptosis by apolipoprotein E4 through low-density lipoprotein receptor-related protein and heterotrimeric GTPases.

31 December 2023

31

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

31 December 2023

33

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Isoform-specific effect of apolipoprotein E on endocytosis of beta-amyloid in cultures of neuroblastoma cells

31 December 2023

34

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Presenilin-1 mutations reduce cytoskeletal association, deregulate neurite growth, and potentiate neuronal dystrophy and tau phosphorylation.

31 December 2023

35

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Inhibition of beta-amyloid formation identifies proteolytic precursors and subcellular site of catabolism

31 December 2023

38

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

31 December 2023

39

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Endogenous presenilin-1 targets to endocytic rather than biosynthetic compartments

31 December 2023

40

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

31 December 2023

Dynein at the cortex

41

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

CLIP-50 immunolocalization during mouse spermiogenesis suggests a role in shaping the sperm nucleus

31 December 2023

43

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

Calcium depletion dissociates and activates heterodimeric notch receptors

31 December 2023

44

1 reference

https://api.crossref.org/works/10.1096/FJ.02-0980FJE

31 December 2023

Identifiers

0 references

1 reference