Leptin induces apoptosis via ERK/cPLA2/cytochrome c pathway in human bone marrow stromal cells (Q38356187)

2 September 2017

Leptin induces apoptosis via ERK/cPLA2/cytochrome c pathway in human bone marrow stromal cells (English)

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2 September 2017

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Ghi Su Kim

1

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2 September 2017

Jeong Soo Hong

2

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2 September 2017

Seung Wook Kim

3

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2 September 2017

Jung-Min Koh

4

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2 September 2017

Chung Sun An

5

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2 September 2017

Je-Yong Choi

6

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2 September 2017

Su-Li Cheng

7

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2 September 2017

language of work or name

English

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publication date

28 March 2003

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Journal of Biological Chemistry

2 September 2017

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2 September 2017

278

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2 September 2017

24

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2 September 2017

21920-21929

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Positional cloning of the mouse obese gene and its human homologue

2 September 2017

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21 January 2018

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Identification and expression cloning of a leptin receptor, OB-R

21 January 2018

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Long form leptin receptor mRNA expression in the brain, pituitary, and other tissues in the pig.

21 January 2018

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21 January 2018

Leptin in reproduction.

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Leptin is a potent stimulator of bone growth in ob/ob mice

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

21 January 2018

1 reference

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Leptin is expressed in and secreted from primary cultures of human osteoblasts and promotes bone mineralization

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

Differentiation of human bone marrow osteogenic stromal cells in vitro: induction of the osteoblast phenotype by dexamethasone

21 January 2018

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Lack of autocrine effects of IL-6 on human bone marrow stromal osteoprogenitor cells.

21 January 2018

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Guanosine 5'-O-(3-thiotriphosphate) (GTPgammaS) stimulation of GLUT4 translocation is tyrosine kinase-dependent

21 January 2018

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PPAR-gamma gene expression is elevated in skeletal muscle of obese and type II diabetic subjects

21 January 2018

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A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

cPLA2 is phosphorylated and activated by MAP kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

Human bone cellsin vitro.

21 January 2018

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Multilineage potential of adult human mesenchymal stem cells

21 January 2018

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Proadipogenic effect of leptin on rat preadipocytes in vitro: activation of MAPK and STAT3 signaling pathways

21 January 2018

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Nuclear hormone receptors and adipogenesis

21 January 2018

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation

21 January 2018

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The ups and downs of MEK kinase interactions

21 January 2018

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Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

Activation of downstream signals by the long form of the leptin receptor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

Abnormal splicing of the leptin receptor in diabetic mice

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204598200

Leptin receptor isoform expression in rat osteoblasts and their functional analysis.

21 January 2018

1 reference

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Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: Impact on differentiation markers, apoptosis, and osteoclastic signaling

21 January 2018

1 reference

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Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204598200

Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

Leptin induces angiopoietin-2 expression in adipose tissues

21 January 2018

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Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

Osteoblast apoptosis and bone turnover

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

BCL-2 family members and the mitochondria in apoptosis

21 January 2018

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Role of poly(ADP-ribose) formation in DNA repair

21 January 2018

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A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage

21 January 2018

1 reference

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

Functional STAT 1 and 3 signaling by the leptin receptor (OB-R); reduced expression of the rat fatty leptin receptor in transfected cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

Divergent signaling capacities of the long and short isoforms of the leptin receptor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

Leptin receptor action in hepatic cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

Different apoptotic pathways mediated by Fas and the tumor-necrosis-factor receptor. Cytosolic phospholipase A2 is not involved in Fas-mediated apoptosis

21 January 2018

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Irreversible inhibition of Ca(2+)-independent phospholipase A2 by methyl arachidonyl fluorophosphonate

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M204598200

Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

21 January 2018

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Leptin Inhibits Osteoclast Generation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M204598200

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2 September 2017

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