The hepatitis C virus protein NS3 suppresses TNF-α-stimulated activation of NF-κB by targeting LUBAC. (Q38420434)

2 September 2017

The hepatitis C virus protein NS3 suppresses TNF-α-stimulated activation of NF-κB by targeting LUBAC. (English)

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2 September 2017

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Genhong Cheng

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2 September 2017

Yongzhi Chen

1

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2 September 2017

Liang He

2

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2 September 2017

Yanan Peng

3

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2 September 2017

Xiaodong Shi

4

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2 September 2017

Jizheng Chen

5

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2 September 2017

Jin Zhong

6

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2 September 2017

Xinwen Chen

7

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2 September 2017

Hongyu Deng

9

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2 September 2017

language of work or name

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17 November 2015

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2 September 2017

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2 September 2017

8

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2 September 2017

ra118

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2 September 2017

403

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TNFR1-induced activation of the classical NF-κB pathway

2 September 2017

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

TNF and ubiquitin at the crossroads of gene activation, cell death, inflammation, and cancer

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

NF-kappaB: much learned, much to learn

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Diverse ubiquitin signaling in NF-κB activation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

The role of ubiquitylation in immune defence and pathogen evasion

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Regulation of NF-κB by ubiquitination

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Linear polyubiquitination: a new regulator of NF-kappaB activation.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

The emerging role of linear ubiquitination in cell signaling

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

A ubiquitin ligase complex assembles linear polyubiquitin chains

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

E3 ubiquitin ligase RNF31 cooperates with DAX-1 in transcriptional repression of steroidogenesis

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Identification, expression, and assay of an oxidation-specific ubiquitin ligase, HOIL-1.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

LUBAC, a novel ubiquitin ligase for linear ubiquitination, is crucial for inflammation and immune responses.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Linear ubiquitination prevents inflammation and regulates immune signalling

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Global epidemiology of hepatitis C virus infection

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Unravelling hepatitis C virus replication from genome to function

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Hepatitis C virus non-structural protein 3 (HCV NS3): a multifunctional antiviral target

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Interaction between the HCV NS3 protein and the host TBK1 protein leads to inhibition of cellular antiviral responses

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Hepatitis C virus RNA replication is resistant to tumour necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

The hepatitis C virus and immune evasion: non-structural 3/4A transgenic mice are resistant to lethal tumour necrosis factor mediated liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Antiviral effect and virus-host interactions in response to alpha interferon, gamma interferon, poly(i)-poly(c), tumor necrosis factor alpha, and ribavirin in hepatitis C virus subgenomic replicons

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

A recombinant adenovirus encoding hepatitis C virus core and E1 proteins protects mice against cytokine-induced liver damage

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Robust hepatitis C virus infection in vitro

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Complete replication of hepatitis C virus in cell culture

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Compensatory mutations in NS3 and NS5A proteins enhance the virus production capability of hepatitis C reporter virus

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Monitoring the Antiviral Effect of Alpha Interferon on Individual Cells

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Mobility analysis of an NS5A-GFP fusion protein in cells actively replicating hepatitis C virus subgenomic RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Hepatitis C virus infection enhances TNFα-induced cell death via suppression of NF-κB.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Hepatitis C virus NS5A and subgenomic replicon activate NF-kappaB via tyrosine phosphorylation of IkappaBalpha and its degradation by calpain protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Small Interfering RNA Targeted to Hepatitis C Virus 5' Nontranslated Region Exerts Potent Antiviral Effect

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Hepatitis C virus infection protein network

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Mechanism Underlying I B Kinase Activation Mediated by the Linear Ubiquitin Chain Assembly Complex

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Interferon-inducible cholesterol-25-hydroxylase inhibits hepatitis C virus replication via distinct mechanisms

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

Telomere maintenance through spatial control of telomeric proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAB2159

10.1126/SCISIGNAL.AAB2159

21 January 2018

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DOI

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2 September 2017

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