Gα12 gep oncogene deregulation of p53-responsive microRNAs promotes epithelial-mesenchymal transition of hepatocellular carcinoma. (Q38435836)

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10 March 2020

title

Gα12 gep oncogene deregulation of p53-responsive microRNAs promotes epithelial-mesenchymal transition of hepatocellular carcinoma (English)

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10 March 2020

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4

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10 March 2020

author name string

Y M Yang

1

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10 March 2020

W H Lee

2

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10 March 2020

C G Lee

3

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10 March 2020

E-S Kim

5

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10 March 2020

S H Kim

6

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10 March 2020

S-K Lee

7

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10 March 2020

C H Lee

8

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10 March 2020

D N Dhanasekaran

9

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10 March 2020

A Moon

10

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10 March 2020

S Hwang

11

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10 March 2020

S J Lee

12

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10 March 2020

J-W Park

13

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10 March 2020

K M Kim

14

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10 March 2020

S G Kim

15

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10 March 2020

language of work or name

English

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publication date

28 July 2014

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10 March 2020

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10 March 2020

volume

34

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10 March 2020

issue

22

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10 March 2020

page(s)

2910-2921

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Tumor-secreted lysophostatidic acid accelerates hepatocellular carcinoma progression by promoting differentiation of peritumoral fibroblasts in myofibroblasts

10 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Receptors coupled to heterotrimeric G proteins of the G12 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Biologic functions of the G12 subfamily of heterotrimeric g proteins: growth, migration, and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Critical role of G(alpha)12 and G(alpha)13 for human small cell lung cancer cell proliferation in vitro and tumor growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

G(alpha)12/13 inhibition enhances the anticancer effect of bortezomib through PSMB5 downregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Abnormal structure and expression of p53 gene in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Potential contribution of tumor suppressor p53 in the host defense against hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Mdm2 links genotoxic stress and metabolism to p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Sphingosine 1-phosphate regulates matrix metalloproteinase-9 expression and breast cell invasion through S1P3-Gαq coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

G(alpha)12-mediated pathway promotes invasiveness of nasopharyngeal carcinoma by modulating actin cytoskeleton reorganization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

G alpha 12/13 basally regulates p53 through Mdm4 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

The gep oncogenes, Galpha(12) and Galpha(13), upregulate the transforming growth factor-beta1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Thrombin induces nitric-oxide synthase via Galpha12/13-coupled protein kinase C-dependent I-kappaBalpha phosphorylation and JNK-mediated I-kappaBalpha degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

TGF-beta-induced epithelial to mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

E-cadherin expression is regulated by miR-192/215 by a mechanism that is independent of the profibrotic effects of transforming growth factor-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Review of miR-200b and cancer chemosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Clinicopathological significance of ZEB1 protein in patients with hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Galpha12 specifically regulates COX-2 induction by sphingosine 1-phosphate. Role for JNK-dependent ubiquitination and degradation of IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Decrease of microRNA-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B, which is reversed by licorice flavonoid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Hemin, an iron-binding porphyrin, inhibits HIF-1α induction through its binding with heat shock protein 90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Human tumor-derived p53 proteins exhibit binding site selectivity and temperature sensitivity for transactivation in a yeast-based assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Microvascular invasion in patients with hepatocellular carcinoma and its predictable clinicopathological factors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.218

Hepatitis B virus X protein sensitizes hepatocellular carcinoma cells to cytolysis induced by E1B-deleted adenovirus through the disruption of p53 function

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25065598