A new synthetic HDAC inhibitor, MHY218, induces apoptosis or autophagy-related cell death in tamoxifen-resistant MCF-7 breast cancer cells (Q38469769)

3 September 2017

A new synthetic HDAC inhibitor, MHY218, induces apoptosis or autophagy-related cell death in tamoxifen-resistant MCF-7 breast cancer cells (English)

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3 September 2017

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Jaewon Lee

6

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author name string

Ji Hye Park

1

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3 September 2017

Mee Young Ahn

2

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3 September 2017

Tae Hyung Kim

3

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3 September 2017

Sungpill Yoon

4

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3 September 2017

Keon Wook Kang

5

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3 September 2017

Hyung Ryong Moon

7

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3 September 2017

Jee H Jung

8

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3 September 2017

Hae Young Chung

9

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3 September 2017

Hyung Sik Kim

10

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3 September 2017

8 October 2011

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Investigational New Drugs

3 September 2017

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3 September 2017

30

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3 September 2017

5

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3 September 2017

1887-1898

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https://scigraph.springernature.com/pub.10.1007/s10637-011-9752-z

3 September 2017

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Enhancement of vascular endothelial growth factor-mediated angiogenesis in tamoxifen-resistant breast cancer cells: role of Pin1 overexpression

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Structural basis for an unexpected mode of SERM-mediated ER antagonism

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A natural histone deacetylase inhibitor, Psammaplin A, induces cell cycle arrest and apoptosis in human endometrial cancer cells

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Mechanism of apicidin-induced cell cycle arrest and apoptosis in Ishikawa human endometrial cancer cells.

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Anticancer activities of histone deacetylase inhibitors

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Hydroxamic acid analogue histone deacetylase inhibitors attenuate estrogen receptor-alpha levels and transcriptional activity: a result of hyperacetylation and inhibition of chaperone function of heat shock protein 90.

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Histone deacetylase inhibition and estrogen signalling in human breast cancer cells.

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Signal therapy of breast cancers by the HDAC inhibitor FK228 that blocks the activation of PAK1 and abrogates the tamoxifen-resistance

21 January 2018

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Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

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Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer.

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Histone deacetylases (HDACs): characterization of the classical HDAC family

21 January 2018

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Inhibitors of histone deacetylase as new anticancer agents

21 January 2018

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Modulation of cell cycles and apoptosis by apicidin in estrogen receptor (ER)-positive and-negative human breast cancer cells

21 January 2018

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Suberoylanilide hydroxamic acid (SAHA) potentiates paclitaxel-induced apoptosis in ovarian cancer cell lines

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Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance

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The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

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21 January 2018

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Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization

21 January 2018

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Altered expression of estrogen-regulated genes in a tamoxifen-resistant and ICI 164,384 and ICI 182,780 sensitive human breast cancer cell line, MCF-7/TAMR-1.

21 January 2018

1 reference

12 December 2020

Inhibition of histone deacetylase 2 increases apoptosis and p21Cip1/WAF1 expression, independent of histone deacetylase 1

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12 December 2020

Suberoylanilide hydroxamic acid (SAHA) induces apoptosis or autophagy-associated cell death in chondrosarcoma cell lines.

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12 December 2020

Transcriptional activation of p21(WAF1/CIP1) by apicidin, a novel histone deacetylase inhibitor

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12 December 2020

Histone deacetylase inhibitors: apoptotic effects and clinical implications (Review).

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12 December 2020

Anticancer effects of the MHY218 novel hydroxamic acid-derived histone deacetylase inhibitor in human ovarian cancer cells

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12 December 2020

10.1007/S10637-011-9752-Z

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DOI

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Dimensions Publication ID

3 September 2017

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