Circulating miRNAs as intercellular messengers, potential biomarkers and therapeutic targets for Type 2 diabetes (Q38537772)

3 September 2017

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title

Circulating miRNAs as intercellular messengers, potential biomarkers and therapeutic targets for Type 2 diabetes (English)

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3 September 2017

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type 2 diabetes

9 December 2023

Gregoryalexander Raciti

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26111035%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Pietro Formisano

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26111035%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Paola Mirra

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26111035%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Cecilia Nigro

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26111035%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Francesca Fiory

4

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13 June 2020

Vittoria D'Esposito

5

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13 June 2020

Francesco Beguinot

7

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13 June 2020

Claudia Miele

8

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13 June 2020

language of work or name

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1 June 2015

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3 September 2017

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13 June 2020

volume

7

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13 June 2020

page(s)

653-667

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13 June 2020

issue

4

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Phenotypic plasticity and the epigenetics of human disease

13 June 2020

cites work

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Epigenetic changes in diabetes.

21 January 2018

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miRNAs: their discovery, biogenesis and mechanism of action

21 January 2018

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Regulation of mRNA translation and stability by microRNAs

21 January 2018

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MicroRNAs and epigenetics

21 January 2018

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An epigenetic feedback regulatory loop involving microRNA-195 and MBD1 governs neural stem cell differentiation

21 January 2018

1 reference

Diabetes mellitus, a microRNA-related disease?

21 January 2018

1 reference

MicroRNAs in metabolism and metabolic disorders

21 January 2018

1 reference

Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs

21 January 2018

1 reference

The Lin28/let-7 axis regulates glucose metabolism

21 January 2018

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MiRNA-21 reverses high glucose and high insulin induced insulin resistance in 3T3-L1 adipocytes through targeting phosphatase and tensin homologue

21 January 2018

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Overexpression of micro ribonucleic acid 29, highly up-regulated in diabetic rats, leads to insulin resistance in 3T3-L1 adipocytes

21 January 2018

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Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes.

21 January 2018

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miR-29a levels are elevated in the db/db mice liver and its overexpression leads to attenuation of insulin action on PEPCK gene expression in HepG2 cells.

21 January 2018

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miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling

21 January 2018

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Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides.

21 January 2018

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Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

21 January 2018

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Controlling SIRT1 expression by microRNAs in health and metabolic disease

21 January 2018

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miRNA-93 inhibits GLUT4 and is overexpressed in adipose tissue of polycystic ovary syndrome patients and women with insulin resistance

21 January 2018

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MicroRNAs 103 and 107 regulate insulin sensitivity

21 January 2018

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The induction of microRNA targeting IRS-1 is involved in the development of insulin resistance under conditions of mitochondrial dysfunction in hepatocytes

21 January 2018

1 reference

Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism

21 January 2018

1 reference

MicroRNA-223 regulates Glut4 expression and cardiomyocyte glucose metabolism

21 January 2018

1 reference

CHANGES IN microRNA (miR) profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes

21 January 2018

1 reference

MicroRNA-494, upregulated by tumor necrosis factor-α, desensitizes insulin effect in C2C12 muscle cells

21 January 2018

1 reference

Sirt1 and mir-9 expression is regulated during glucose-stimulated insulin secretion in pancreatic β-islets

21 January 2018

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MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells

21 January 2018

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miR-29a and miR-29b contribute to pancreatic beta-cell-specific silencing of monocarboxylate transporter 1 (Mct1)

21 January 2018

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Changes in microRNA expression contribute to pancreatic β-cell dysfunction in prediabetic NOD mice

21 January 2018

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Identification of glucose-regulated miRNAs from pancreatic {beta} cells reveals a role for miR-30d in insulin transcription

21 January 2018

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MicroRNA-30d induces insulin transcription factor MafA and insulin production by targeting mitogen-activated protein 4 kinase 4 (MAP4K4) in pancreatic β-cells

21 January 2018

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Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction

21 January 2018

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Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells.

21 January 2018

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MiR-34, SIRT1 and p53: the feedback loop

21 January 2018

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miR-34a repression of SIRT1 regulates apoptosis

21 January 2018

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Differential glucose-regulation of microRNAs in pancreatic islets of non-obese type 2 diabetes model Goto-Kakizaki rat

21 January 2018

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Up-regulated pancreatic tissue microRNA-375 associates with human type 2 diabetes through beta-cell deficit and islet amyloid deposition.

21 January 2018

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Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development

21 January 2018

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A pancreatic islet-specific microRNA regulates insulin secretion

21 January 2018

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miR-375 maintains normal pancreatic alpha- and beta-cell mass

21 January 2018

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miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells

21 January 2018

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Enhanced levels of microRNA-125b in vascular smooth muscle cells of diabetic db/db mice lead to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1.

21 January 2018

1 reference

miRNA-1 regulates endothelin-1 in diabetes.

21 January 2018

1 reference

MiR-21 is overexpressed in response to high glucose and protects endothelial cells from apoptosis.

21 January 2018

1 reference

Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes

21 January 2018

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miR-146a-Mediated extracellular matrix protein production in chronic diabetes complications.

21 January 2018

1 reference

MicroRNA-221 regulates high glucose-induced endothelial dysfunction

21 January 2018

1 reference

MIR221/MIR222-driven post-transcriptional regulation of P27KIP1 and P57KIP2 is crucial for high-glucose- and AGE-mediated vascular cell damage

21 January 2018

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Deregulation of microRNA-503 contributes to diabetes mellitus-induced impairment of endothelial function and reparative angiogenesis after limb ischemia

21 January 2018

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Cell to cell signalling via exosomes through esRNA

21 January 2018

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Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

21 January 2018

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Detection of microRNA expression in human peripheral blood microvesicles

21 January 2018

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Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma

21 January 2018

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Circulating microRNAs as stable blood-based markers for cancer detection

21 January 2018

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Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

21 January 2018

1 reference

Embryonal carcinoma cell induction of miRNA and mRNA changes in co-cultured prostate stromal fibromuscular cells

21 January 2018

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The microRNA spectrum in 12 body fluids

21 January 2018

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Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

21 January 2018

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Characterization of extracellular circulating microRNA

21 January 2018

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Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

21 January 2018

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MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

21 January 2018

1 reference

Characterization of levels and cellular transfer of circulating lipoprotein-bound microRNAs

21 January 2018

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MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic disease.

21 January 2018

1 reference

MicroRNAs as early biomarkers in obesity and related metabolic and cardiovascular diseases.

21 January 2018

1 reference

Salivary microRNA: discovery, characterization, and clinical utility for oral cancer detection

21 January 2018

1 reference

A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer

21 January 2018

1 reference

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes.

21 January 2018

1 reference

Secretory mechanisms and intercellular transfer of microRNAs in living cells

21 January 2018

1 reference

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

21 January 2018

1 reference

Intercellular nanovesicle-mediated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth

21 January 2018

1 reference

Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells

21 January 2018

1 reference

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

21 January 2018

1 reference

Macrophage microvesicles induce macrophage differentiation and miR-223 transfer

21 January 2018

1 reference

Microvesicle-delivery miR-150 promotes tumorigenesis by up-regulating VEGF, and the neutralization of miR-150 attenuate tumor development

21 January 2018

1 reference

Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection

21 January 2018

1 reference

AngiomiR-126 expression and secretion from circulating CD34(+) and CD14(+) PBMCs: role for proangiogenic effects and alterations in type 2 diabetics

21 January 2018

1 reference

Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs

21 January 2018

1 reference

Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation

21 January 2018

1 reference

Take-over: multiple mechanisms of inter-adipocyte communication

21 January 2018

1 reference

Clinical relevance of circulating cell-free microRNAs in cancer

21 January 2018

1 reference

Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study.

21 January 2018

1 reference

Circulating miRNA profiles in patients with metabolic syndrome

21 January 2018

1 reference

Treatment of HCV infection by targeting microRNA

21 January 2018

1 reference

Miravirsen (SPC3649) can inhibit the biogenesis of miR-122.

21 January 2018

1 reference

Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver

21 January 2018

1 reference

Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failure

21 January 2018

1 reference

A cardiac microRNA governs systemic energy homeostasis by regulation of MED13

21 January 2018

1 reference

Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells

21 January 2018

1 reference

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/EPI.15.18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26111035%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference