Tumor suppressor or oncogene? A critical role of the human papillomavirus (HPV) E2 protein in cervical cancer progression. (Q38561398)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21968515%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

review article

1 reference

title

Tumor suppressor or oncogene? A critical role of the human papillomavirus (HPV) E2 protein in cervical cancer progression (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21968515%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

main subject

cervix uterine cancer

1 reference

Sophie Bellanger

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21968515%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Chye Ling Tan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21968515%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Yue Zhen Xue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21968515%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Sébastien Teissier

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21968515%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Françoise Thierry

5

1 reference

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14 February 2020

publication date

24 January 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21968515%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Cancer Research

14 February 2020

published in

1 reference

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14 February 2020

volume

1

1 reference

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14 February 2020

issue

3

1 reference

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14 February 2020

page(s)

373-389

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Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression

14 February 2020

cites work

1 reference

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Cellular FLICE-inhibitory protein (c-FLIP) signalling: a key regulator of receptor-mediated apoptosis in physiologic context and in cancer

6 September 2017

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Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repression

6 September 2017

1 reference

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A novel interaction between the human papillomavirus type 16 E2 and E1--E4 proteins leads to stabilization of E2.

6 September 2017

1 reference

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Brd4 regulation of papillomavirus protein E2 stability

6 September 2017

1 reference

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BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis

6 September 2017

1 reference

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Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses

6 September 2017

1 reference

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Dynamic expression of epidermal caspase 8 simulates a wound healing response

6 September 2017

1 reference

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Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding

6 September 2017

1 reference

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Papillomavirus E2 proteins and the host BRD4 protein associate with transcriptionally active cellular chromatin

6 September 2017

1 reference

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Transcriptional regulation of the papillomavirus oncogenes by cellular and viral transcription factors in cervical carcinoma

6 September 2017

1 reference

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Chromatin adaptor Brd4 modulates E2 transcription activity and protein stability

6 September 2017

1 reference

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The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

6 September 2017

1 reference

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Dimerization of the papillomavirus E2 protein is required for efficient mitotic chromosome association and Brd4 binding

6 September 2017

1 reference

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Inhibition of transcription and DNA replication by the papillomavirus E8-E2C protein is mediated by interaction with corepressor molecules

6 September 2017

1 reference

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Search for cellular partners of human papillomavirus type 16 E2 protein

6 September 2017

1 reference

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Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer

6 September 2017

1 reference

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Brd4-independent transcriptional repression function of the papillomavirus e2 proteins

6 September 2017

1 reference

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The spindle-assembly checkpoint in space and time

6 September 2017

1 reference

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Mad2 overexpression promotes aneuploidy and tumorigenesis in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Structure of the papillomavirus DNA-tethering complex E2:Brd4 and a peptide that ablates HPV chromosomal association

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

ChlR1 is required for loading papillomavirus E2 onto mitotic chromosomes and viral genome maintenance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Brd4 is required for e2-mediated transcriptional activation but not genome partitioning of all papillomaviruses

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Brd4 links chromatin targeting to HPV transcriptional silencing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Partitioning viral genomes in mitosis: same idea, different targets

6 September 2017

1 reference

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E2 proteins from high- and low-risk human papillomavirus types differ in their ability to bind p53 and induce apoptotic cell death

6 September 2017

1 reference

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Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function

6 September 2017

1 reference

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Papillomavirus E2 protein interacts with and stimulates human topoisomerase I.

6 September 2017

1 reference

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Variations in the association of papillomavirus E2 proteins with mitotic chromosomes

6 September 2017

1 reference

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The mitotic chromosome binding activity of the papillomavirus E2 protein correlates with interaction with the cellular chromosomal protein, Brd4.

6 September 2017

1 reference

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The X-ray structure of the papillomavirus helicase in complex with its molecular matchmaker E2.

6 September 2017

1 reference

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Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes

6 September 2017

1 reference

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Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex

6 September 2017

1 reference

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Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase

6 September 2017

1 reference

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Direct interaction between nucleosome assembly protein 1 and the papillomavirus E2 proteins involved in activation of transcription

6 September 2017

1 reference

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Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase

6 September 2017

1 reference

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Cooperative activation of human papillomavirus type 8 gene expression by the E2 protein and the cellular coactivator p300.

6 September 2017

1 reference

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A Functional interaction between the human papillomavirus 16 transcription/replication factor E2 and the DNA damage response protein TopBP1

6 September 2017

1 reference

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Functional interaction between p/CAF and human papillomavirus E2 protein

6 September 2017

1 reference

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Skp2 is oncogenic and overexpressed in human cancers

6 September 2017

1 reference

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Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways

6 September 2017

1 reference

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Rapid induction of senescence in human cervical carcinoma cells

6 September 2017

1 reference

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Proteasome-mediated degradation of the papillomavirus E2-TA protein is regulated by phosphorylation and can modulate viral genome copy number

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

AMF-1/Gps2 binds p300 and enhances its interaction with papillomavirus E2 proteins

6 September 2017

1 reference

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cAMP response element-binding protein-binding protein binds to human papillomavirus E2 protein and activates E2-dependent transcription

6 September 2017

1 reference

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Interaction between the HPV-16 E2 transcriptional activator and p53.

6 September 2017

1 reference

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Alleviation of human papillomavirus E2-mediated transcriptional repression via formation of a TATA binding protein (or TFIID)-TFIIB-RNA polymerase II-TFIIF preinitiation complex

6 September 2017

1 reference

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SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

6 September 2017

1 reference

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Transactivation-competent bovine papillomavirus E2 protein is specifically required for efficient repression of human papillomavirus oncogene expression and for acute growth inhibition of cervical carcinoma cell lines

6 September 2017

1 reference

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Segregation of viral plasmids depends on tethering to chromosomes and is regulated by phosphorylation

6 September 2017

1 reference

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Bovine papillomavirus type 1 genomes and the E2 transactivator protein are closely associated with mitotic chromatin.

6 September 2017

1 reference

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Functional interaction of a novel cellular protein with the papillomavirus E2 transactivation domain

6 September 2017

1 reference

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Functional interactions between papillomavirus E1 and E2 proteins.

6 September 2017

1 reference

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Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis

6 September 2017

1 reference

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Abrogation of a mitotic checkpoint by E2 proteins from oncogenic human papillomaviruses correlates with increased turnover of the p53 tumor suppressor protein.

6 September 2017

1 reference

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The E2 transcriptional repressor can compensate for Sp1 activation of the human papillomavirus type 18 early promoter

6 September 2017

1 reference

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The bovine papillomavirus 1 E2 protein contains two activation domains: one that interacts with TBP and another that functions after TBP binding.

6 September 2017

1 reference

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Bovine papillomavirus type 1 E2 transcriptional regulators directly bind two cellular transcription factors, TFIID and TFIIB

6 September 2017

1 reference

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Cellular factors required for papillomavirus DNA replication.

6 September 2017

1 reference

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Suppression of cellular proliferation by the papillomavirus E2 protein

6 September 2017

1 reference

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Characterization of a transcriptional promoter of human papillomavirus 18 and modulation of its expression by simian virus 40 and adenovirus early antigens

6 September 2017

1 reference

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Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein

6 September 2017

1 reference

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Identification of the human papilloma virus-1a E4 gene products

6 September 2017

1 reference

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A dimer of BPV-1 E2 containing a protease resistant core interacts with its DNA target

6 September 2017

1 reference

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Structural and mutational analysis of E2 trans-activating proteins of papillomaviruses reveals three distinct functional domains.

6 September 2017

1 reference

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E2 polypeptides encoded by bovine papillomavirus type 1 form dimers through the common carboxyl-terminal domain: transactivation is mediated by the conserved amino-terminal domain

6 September 2017

1 reference

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The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes

6 September 2017

1 reference

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The human papillomavirus type 18 (HPV18) E2 gene product is a repressor of the HPV18 regulatory region in human keratinocytes.

6 September 2017

1 reference

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Quantitative keratinocyte assay detects two biological activities of human papillomavirus DNA and identifies viral types associated with cervical carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Human papillomavirus type 16 alters human epithelial cell differentiation in vitro

6 September 2017

1 reference

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Characterization of primary human keratinocytes transformed by human papillomavirus type 18.

6 September 2017

1 reference

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Cooperative activation of transcription by bovine papillomavirus type 1 E2 can occur over a large distance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Mutational analysis of cis elements involved in E2 modulation of human papillomavirus type 16 P97 and type 18 P105 promoters

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Crystal structure at 1.7 A of the bovine papillomavirus-1 E2 DNA-binding domain bound to its DNA target

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Two AP1 sites binding JunB are essential for human papillomavirus type 18 transcription in keratinocytes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

During negative regulation of the human papillomavirus-16 E6 promoter, the viral E2 protein can displace Sp1 from a proximal promoter element

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Triggering of death receptor apoptotic signaling by human papillomavirus 16 E2 protein in cervical cancer cell lines is mediated by interaction with c-FLIP.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

hSNF5 is required for human papillomavirus E2-driven transcriptional activation and DNA replication

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Stability of the human papillomavirus type 18 E2 protein is regulated by a proteasome degradation pathway through its amino-terminal transactivation domain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Long-term episomal maintenance of bovine papillomavirus type 1 plasmids is determined by attachment to host chromosomes, which Is mediated by the viral E2 protein and its binding sites

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Functional interaction of the bovine papillomavirus E2 transactivation domain with TFIIB.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

The human papillomavirus E7-E2 interaction mechanism in vitro reveals a finely tuned system for modulating available E7 and E2 proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

The human papillomavirus type 18 E2 protein is a cell cycle-dependent target of the SCFSkp2 ubiquitin ligase.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Proteasomal degradation of the papillomavirus E2 protein is inhibited by overexpression of bromodomain-containing protein 4.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Interaction between human papillomavirus type 5 E2 and polo-like kinase 1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

The human papillomavirus type 8 E2 tethering protein targets the ribosomal DNA loci of host mitotic chromosomes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Mitotic checkpoint genes, hsMAD2 and BubR1, in oesophageal squamous cancer cells and their association with 5-fluorouracil and cisplatin-based radiochemotherapy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Dimerization of the human papillomavirus type 16 E2 N terminus results in DNA looping within the upstream regulatory region

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

TopBP1 regulates human papillomavirus type 16 E2 interaction with chromatin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Interaction of papillomavirus E2 protein with the Brm chromatin remodeling complex leads to enhanced transcriptional activation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Regulation of human papillomavirus type 16 E7 activity through direct protein interaction with the E2 transcriptional activator

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

High-risk but not low-risk HPV E2 proteins bind to the APC activators Cdh1 and Cdc20 and cause genomic instability

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Nucleo-cytoplasmic shuttling of high risk human Papillomavirus E2 proteins induces apoptosis.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

BRCA1 associates with human papillomavirus type 18 E2 and stimulates E2-dependent transcription

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Different mechanisms contribute to the E2-mediated transcriptional repression of human papillomavirus type 18 viral oncogenes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Control of human papillomavirus type 11 origin of replication by the E2 family of transcription regulatory proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

The hinge region of the human papillomavirus type 8 E2 protein activates the human p21(WAF1/CIP1) promoter via interaction with Sp1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Papillomavirus E2 induces p53-independent apoptosis in HeLa cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Expression of human papillomavirus 16 E2 protein in Schizosaccharomyces pombe delays the initiation of mitosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

The BPV1-E2 trans-acting protein can be either an activator or a repressor of the HPV18 regulatory region

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Inverse relationship between the expression of the human papillomavirus type 16 transcription factor E2 and virus DNA copy number during the progression of cervical intraepithelial neoplasia

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Control of papillomavirus DNA replication and transcription.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Human papillomavirus type 16 DNA sequence

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Structure and transcription of human papillomavirus sequences in cervical carcinoma cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Properties of a non-tumorigenic human cervical keratinocyte cell line

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Functional analysis of E2-mediated repression of the HPV18 P105 promoter

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

HPV16 E2 is an immediate early marker of viral infection, preceding E7 expression in precursor structures of cervical carcinoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

BUBR1 expression in benign oral lesions and squamous cell carcinomas: correlation with human papillomavirus.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

The clinicopathological significance of BUBR1 overexpression in hepatocellular carcinoma.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Interaction of the betapapillomavirus E2 tethering protein with mitotic chromosomes

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Tax1BP1 interacts with papillomavirus E2 and regulates E2-dependent transcription and stability

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

The Mdm2 ubiquitin ligase enhances transcriptional activity of human papillomavirus E2.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Overexpression of the mitotic checkpoint genes BUB1 and BUBR1 is associated with genomic complexity in clear cell kidney carcinomas.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

The human papillomavirus type 8 E2 gene encodes a transforming activity sufficient for skin tumor formation in transgenic mice.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Type-dependent integration frequency of human papillomavirus genomes in cervical lesions.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

BRCA status, molecular markers, and clinical variables in early, conservatively managed breast cancer

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Overexpression of the mitotic checkpoint genes BUB1, BUBR1, and BUB3 in gastric cancer--association with tumour cell proliferation.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Transcription-independent triggering of the extrinsic pathway of apoptosis by human papillomavirus 18 E2 protein.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Novel cellular interacting partners of the human papillomavirus 16 transcription/replication factor E2.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Functional interaction between human papillomavirus type 18 E2 and poly(ADP-ribose) polymerase 1.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

The human papillomavirus (HPV) 16 E2 protein induces apoptosis in the absence of other HPV proteins and via a p53-dependent pathway.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

Expression patterns of the human papillomavirus type 16 transcription factor E2 in low- and high-grade cervical intraepithelial neoplasia

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

p53 and pRb prevent rereplication in response to microtubule inhibitors by mediating a reversible G1 arrest.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3180061

The human papillomavirus type 8 E2 protein induces skin tumors in transgenic mice

31 August 2018

1 reference

12 December 2020

Expression of the HPV11 E2 gene in transgenic mice does not result in alterations of the phenotypic pattern.

1 reference

12 December 2020

Interaction of human papillomavirus 8 regulatory proteins E2, E6 and E7 with components of the TFIID complex

1 reference

12 December 2020

A human papillomavirus E2 transcriptional activator. The interactions with cellular splicing factors and potential function in pre-mRNA processing

1 reference

12 December 2020

TAF1 interacts with and modulates human papillomavirus 16 E2-dependent transcriptional regulation

1 reference

12 December 2020

A p53-dependent mouse spindle checkpoint

1 reference

12 December 2020

Direct activation of caspase 8 by the proapoptotic E2 protein of HPV18 independent of adaptor proteins

1 reference

12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21968515%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PubMed publication ID

21968515

1 reference