A highly conserved NF-κB-responsive enhancer is critical for thymic expression of Aire in mice. (Q38585843)

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23 February 2020

title

A highly conserved NF-κB-responsive enhancer is critical for thymic expression of Aire in mice (English)

1 reference

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23 February 2020

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10

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23 February 2020

Pärt Peterson

12

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23 February 2020

Uku Haljasorg

1

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23 February 2020

Mario Saare

3

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23 February 2020

4

Mithu Guha

1 reference

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23 February 2020

Julia Maslovskaja

5

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Julia Maslovskaja

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23 February 2020

Maire Pihlap

8

object named as

Maire Pihlap

1 reference

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23 February 2020

Anu Remm

7

object named as

Anu Remm

1 reference

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23 February 2020

author name string

Rudolf Bichele

2

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23 February 2020

Karin Kõnd

6

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23 February 2020

Laura Tomson

9

1 reference

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23 February 2020

Martti Laan

11

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23 February 2020

language of work or name

English

0 references

publication date

26 October 2015

1 reference

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European Journal of Immunology

23 February 2020

published in

1 reference

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23 February 2020

volume

45

1 reference

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23 February 2020

issue

12

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23 February 2020

page(s)

3246-3256

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Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see)

23 February 2020

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Generating intrathymic microenvironments to establish T-cell tolerance.

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Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.

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A central role for central tolerance

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Projection of an immunological self shadow within the thymus by the aire protein

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Transcriptional regulation by AIRE: molecular mechanisms of central tolerance

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Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism

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Positional cloning of the APECED gene

21 January 2018

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Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED): a model disease to study molecular aspects of endocrine autoimmunity

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An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

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Lymphopenia-induced proliferation in aire-deficient mice helps to explain their autoimmunity and differences from human patients

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Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1

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Post-Aire Maturation of Thymic Medullary Epithelial Cells Involves Selective Expression of Keratinocyte-Specific Autoantigens

21 January 2018

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Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation

21 January 2018

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Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels

21 January 2018

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RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla

21 January 2018

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Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire

21 January 2018

1 reference

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Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.

21 January 2018

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Deletional tolerance mediated by extrathymic Aire-expressing cells

21 January 2018

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Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells

21 January 2018

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Expression of Aire and the early wave of apoptosis in spermatogenesis

21 January 2018

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Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction.

21 January 2018

1 reference

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The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.

21 January 2018

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Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors

21 January 2018

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The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance.

21 January 2018

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Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium

21 January 2018

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TNF receptor family signaling in the development and functions of medullary thymic epithelial cells

21 January 2018

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DNA methylation signatures of the AIRE promoter in thymic epithelial cells, thymomas and normal tissues.

21 January 2018

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Isolation and characterization of the mouse Aire gene.

21 January 2018

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Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis.

21 January 2018

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Isolation and initial characterization of the mouse Dnmt3l gene.

21 January 2018

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Modulation of Aire regulates the expression of tissue-restricted antigens

21 January 2018

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Autoimmune regulator deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytes

21 January 2018

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Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development

21 January 2018

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Contrasting models for the roles of Aire in the differentiation program of epithelial cells in the thymic medulla

21 January 2018

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Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance

21 January 2018

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Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance

21 January 2018

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Aire-dependent thymic development of tumor-associated regulatory T cells

21 January 2018

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A unified architecture of transcriptional regulatory elements

21 January 2018

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Aire-deficient C57BL/6 mice mimicking the common human 13-base pair deletion mutation present with only a mild autoimmune phenotype

21 January 2018

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Modifier loci condition autoimmunity provoked by Aire deficiency

21 January 2018

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Communication between NF-kappa B and Sp1 controls histone acetylation within the proximal promoter of the monocyte chemoattractant protein 1 gene

21 January 2018

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Characterization of regulatory elements and methylation pattern of the autoimmune regulator (AIRE) promoter

21 January 2018

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Q2ChIP, a quick and quantitative chromatin immunoprecipitation assay, unravels epigenetic dynamics of developmentally regulated genes in human carcinoma cells

21 January 2018

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Quantitative analysis of chromosome conformation capture assays (3C-qPCR).

21 January 2018

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Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Ets transcription factors regulate AIRE gene promoter

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545928

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/EJI.201545928

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26364592%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference