AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa (Q38585967)

4 September 2017

AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa (English)

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4 September 2017

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Deniz Dalkara

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John G. Flannery

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John G Flannery

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author name string

Kathleen D Kolstad

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4 September 2017

Karen I Guerin

3

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4 September 2017

Natalie V Hoffmann

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4 September 2017

Meike Visel

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4 September 2017

Ryan R Klimczak

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4 September 2017

David V Schaffer

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4 September 2017

26 April 2011

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4 September 2017

7

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inferred from page(s)

published in

Molecular Therapy

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4 September 2017

19

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4 September 2017

1602-1608

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4 September 2017

9

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describes a project that uses

4 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3182364/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells

6 September 2017

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Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous

6 September 2017

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AAV-1-mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells

6 September 2017

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Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress

6 September 2017

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High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors

6 September 2017

1 reference

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Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics

6 September 2017

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Self-complementary AAV vectors; advances and applications

6 September 2017

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Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses

6 September 2017

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Effect of gene therapy on visual function in Leber's congenital amaurosis

6 September 2017

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Safety and efficacy of gene transfer for Leber's congenital amaurosis

6 September 2017

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Production and characterization of adeno-associated viral vectors

6 September 2017

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Targeted transgene expression in muller glia of normal and diseased retinas using lentiviral vectors

6 September 2017

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Perspective on genes and mutations causing retinitis pigmentosa

6 September 2017

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6 September 2017

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Müller cells in the healthy and diseased retina

6 September 2017

1 reference

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Long-term safety of GDNF gene delivery in the retina

6 September 2017

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Recombinant AAV-mediated gene transfer to the retina: gene therapy perspectives

6 September 2017

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Adeno-associated viral vectors for retinal gene transfer.

6 September 2017

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Retinitis pigmentosa: genes, proteins and prospects

6 September 2017

1 reference

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Role of Muller cells in retinal degenerations

6 September 2017

1 reference

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Novel AAV serotypes for improved ocular gene transfer

6 September 2017

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Ex vivo gene therapy using intravitreal injection of GDNF-secreting mouse embryonic stem cells in a rat model of retinal degeneration.

14 September 2017

1 reference

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In contrast to AAV-mediated Cntf expression, AAV-mediated Gdnf expression enhances gene replacement therapy in rodent models of retinal degeneration

14 September 2017

1 reference

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Glial cell line derived neurotrophic factor delays photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa

14 September 2017

1 reference

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Two animal models of retinal degeneration are rescued by recombinant adeno-associated virus-mediated production of FGF-5 and FGF-18.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182364

Glial cell line-derived neurotrophic factor induces histologic and functional protection of rod photoreceptors in the rd/rd mouse.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182364

Changes in adeno-associated virus-mediated gene delivery in retinal degeneration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182364

Mechanical injury increases bFGF and CNTF mRNA expression in the mouse retina

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182364

Basic fibroblast growth factor and local injury protect photoreceptors from light damage in the rat

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182364

Ocular gene transfer with self-complementary AAV vectors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182364

Long-term protection of retinal structure but not function using RAAV.CNTF in animal models of retinitis pigmentosa

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182364

Retinal degeneration is slowed in transgenic rats by AAV-mediated delivery of FGF-2.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3182364

Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor

31 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21522134

12 December 2020

inferred from PubMed ID database lookup

Injury-induced upregulation of bFGF and CNTF mRNAS in the rat retina

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21522134

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/MT.2011.62

1 reference

4 September 2017

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4 September 2017

1 reference