Acellular approaches for regenerative medicine: on the verge of clinical trials with extracellular membrane vesicles? (Q38657237)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26631254%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Acellular approaches for regenerative medicine: on the verge of clinical trials with extracellular membrane vesicles? (English)

1 reference

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1 March 2020

main subject

regenerative medicine

1 reference

3

1 reference

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1 March 2020

Nunzio Iraci

4

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1 March 2020

author name string

Almudena Fuster-Matanzo

1

1 reference

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1 March 2020

Florian Gessler

2

1 reference

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1 March 2020

Stefano Pluchino

5

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1 March 2020

publication date

2 December 2015

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Stem Cell Research & Therapy

1 March 2020

published in

1 reference

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1 March 2020

volume

6

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1 March 2020

page(s)

227

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Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges.

1 March 2020

cites work

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Microvesicles derived from human Wharton's Jelly mesenchymal stromal cells ameliorate renal ischemia-reperfusion injury in rats by suppressing CX3CL1.

6 September 2017

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6 September 2017

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Dynamic biodistribution of extracellular vesicles in vivo using a multimodal imaging reporter

6 September 2017

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A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy.

6 September 2017

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6 September 2017

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6 September 2017

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IFNγ-stimulated dendritic cell exosomes as a potential therapeutic for remyelination

6 September 2017

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Extracellular vesicles derived from gut microbiota, especially Akkermansia muciniphila, protect the progression of dextran sulfate sodium-induced colitis

6 September 2017

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CD4+CD25+ regulatory T cells-derived exosomes prolonged kidney allograft survival in a rat model

6 September 2017

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Host matrix modulation by tumor exosomes promotes motility and invasiveness

6 September 2017

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Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication

6 September 2017

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Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro

6 September 2017

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A pathogenic picornavirus acquires an envelope by hijacking cellular membranes

6 September 2017

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6 September 2017

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6 September 2017

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Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells

6 September 2017

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Exosomes derived from human umbilical cord mesenchymal stem cells alleviate liver fibrosis

6 September 2017

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Bone marrow-derived mesenchymal stem cells repaired but did not prevent gentamicin-induced acute kidney injury through paracrine effects in rats

6 September 2017

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6 September 2017

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6 September 2017

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Transfer of vesicles from schwann cells to axons: a novel mechanism of communication in the peripheral nervous system

6 September 2017

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Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes.

6 September 2017

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Exosome-mediated transfer of miR-133b from multipotent mesenchymal stromal cells to neural cells contributes to neurite outgrowth

6 September 2017

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Membrane vesicle release in bacteria, eukaryotes, and archaea: a conserved yet underappreciated aspect of microbial life

6 September 2017

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Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brain

6 September 2017

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Exosome secretion: molecular mechanisms and roles in immune responses

6 September 2017

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Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

6 September 2017

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A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes

6 September 2017

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Secretory mechanisms and intercellular transfer of microRNAs in living cells

6 September 2017

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Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

6 September 2017

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Mesenchymal stem cell-derived microvesicles protect against acute tubular injury

6 September 2017

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Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR

6 September 2017

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Shedding microvesicles: artefacts no more

6 September 2017

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6 September 2017

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Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

6 September 2017

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Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

6 September 2017

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A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer

6 September 2017

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Exosomes: composition, biogenesis and function

6 September 2017

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Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes)

6 September 2017

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Bioinspired exosome-mimetic nanovesicles for targeted delivery of chemotherapeutics to malignant tumors

6 September 2017

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Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?

6 September 2017

1 reference

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Microvesicle-associated AAV vector as a novel gene delivery system

6 September 2017

1 reference

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Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer

6 September 2017

1 reference

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Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization.

14 September 2017

1 reference

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Proteomic analysis of microvesicles derived from human mesenchymal stem cells

14 September 2017

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Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction and gene regulation

25 September 2017

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CD169 mediates the capture of exosomes in spleen and lymph node.

23 June 2018

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As we wait: coping with an imperfect nomenclature for extracellular vesicles

23 June 2018

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Transfer of growth factor receptor mRNA via exosomes unravels the regenerative effect of mesenchymal stem cells

23 June 2018

1 reference

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Brain delivery of olanzapine by intranasal administration of transfersomal vesicles.

23 June 2018

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Immunosuppressive exosomes from TGF-β1 gene-modified dendritic cells attenuate Th17-mediated inflammatory autoimmune disease by inducing regulatory T cells

23 June 2018

1 reference

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Exosome secretion ameliorates lysosomal storage of cholesterol in Niemann-Pick type C disease

23 June 2018

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Extracellular vesicles from human cardiac progenitor cells inhibit cardiomyocyte apoptosis and improve cardiac function after myocardial infarction.

23 June 2018

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Noninvasive in vivo monitoring of extracellular vesicles

31 August 2018

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Schwann cell-derived exosomes enhance axonal regeneration in the peripheral nervous system

31 August 2018

1 reference

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Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles.

31 August 2018

1 reference

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Route of delivery, cell retention, and efficiency of polymeric microcapsules in cellular cardiomyoplasty.

31 August 2018

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Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury.

31 August 2018

1 reference

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Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells

31 August 2018

1 reference

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Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59.

31 August 2018

1 reference

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Production and characterization of clinical grade exosomes derived from dendritic cells.

31 August 2018

1 reference

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Targeting Tumor Antigens to Secreted Membrane Vesicles In vivo Induces Efficient Antitumor Immune Responses

31 August 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13287-015-0232-9

Updated Technology to Produce Highly Immunogenic Dendritic Cell-derived Exosomes of Clinical Grade

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13287-015-0232-9

Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13287-015-0232-9

Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13287-015-0232-9

Secreted monocytic miR-150 enhances targeted endothelial cell migration

21 January 2018

1 reference

12 December 2020

MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease

1 reference

12 December 2020

Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement

1 reference

12 December 2020

Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer

1 reference

12 December 2020

10.1186/S13287-015-0232-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26631254%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26631254%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

26631254

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26631254%20AND%20SRC:MED&resulttype=core&format=json