Identification of Novel Vacuolin-1 Analogues as Autophagy Inhibitors by Virtual Drug Screening and Chemical Synthesis. (Q38677621)

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21 March 2020

title

Identification of Novel Vacuolin-1 Analogues as Autophagy Inhibitors by Virtual Drug Screening and Chemical Synthesis (English)

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21 March 2020

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7

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21 March 2020

author name string

Chang Chen

1

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21 March 2020

Yingying Lu

2

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21 March 2020

Ho Ming Siu

3

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21 March 2020

Jintao Guan

4

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21 March 2020

LongChao Zhu

5

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21 March 2020

Shuang Zhang

6

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21 March 2020

Liangren Zhang

8

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21 March 2020

language of work or name

English

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publication date

27 May 2017

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21 March 2020

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21 March 2020

volume

22

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21 March 2020

issue

6

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Creative Commons Attribution 4.0 International

21 March 2020

copyright license

start time

27 May 2017

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Autophagosome Maturation and Fusion

21 January 2018

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Roles of autophagy and mTOR signaling in neuronal differentiation of mouse neuroblastoma cells

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The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14.

21 January 2018

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Autophagy function and its relationship to pathology, clinical applications, drug metabolism and toxicity

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Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders

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21 January 2018

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The role of autophagy in cancer development and response to therapy.

21 January 2018

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Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

21 January 2018

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The dual role of autophagy in cancer

21 January 2018

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Co-targeting of EGFR and autophagy signaling is an emerging treatment strategy in metastatic colorectal cancer

21 January 2018

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Inhibition of autophagy enhances the selective anti-cancer activity of tigecycline to overcome drug resistance in the treatment of chronic myeloid leukemia

21 January 2018

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Therapeutic Targeting of Autophagy

21 January 2018

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Chloroquine in cancer therapy: a double-edged sword of autophagy.

21 January 2018

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Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase

21 January 2018

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Exo1: a new chemical inhibitor of the exocytic pathway

21 January 2018

1 reference

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Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A.

21 January 2018

1 reference

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Vacuolin-1 inhibits autophagy by impairing lysosomal maturation via PIKfyve inhibition.

21 January 2018

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Virtual screening for novel Atg5–Atg16 complex inhibitors for autophagy modulation

21 January 2018

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10.3390/MOLECULES22060891

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28555021%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28555021%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

28555021

1 reference