Reactive oxygen species and p38 mitogen-activated protein kinase mediate tumor necrosis factor α-converting enzyme (TACE/ADAM-17) activation in primary human monocytes. (Q38734413)

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scientific article published on 24 August 2011

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English	Reactive oxygen species and p38 mitogen-activated protein kinase mediate tumor necrosis factor α-converting enzyme (TACE/ADAM-17) activation in primary human monocytes.	scientific article published on 24 August 2011

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11 February 2020

Reactive oxygen species and p38 mitogen-activated protein kinase mediate tumor necrosis factor α-converting enzyme (TACE/ADAM-17) activation in primary human monocytes (English)

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11 February 2020

reactive oxygen species

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8

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11 February 2020

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Alasdair J Scott

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11 February 2020

Kieran P O'Dea

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11 February 2020

David O'Callaghan

3

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11 February 2020

Lynn Williams

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11 February 2020

Justina O Dokpesi

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11 February 2020

Louise Tatton

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11 February 2020

Jonathan M Handy

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11 February 2020

Masao Takata

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24 August 2011

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11 February 2020

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11

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Journal of Biological Chemistry

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11 February 2020

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11 February 2020

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11 February 2020

35466-35476

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11 February 2020

Studies on the role of acid sphingomyelinase and ceramide in the regulation of tumor necrosis factor alpha (TNFalpha)-converting enzyme activity and TNFalpha secretion in macrophages

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The ADAM metalloproteinases

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Disulfide bonds as switches for protein function

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Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.

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Presence of closely spaced protein thiols on the surface of mammalian cells.

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Reactive oxygen species mediate tumor necrosis factor alpha-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetate

1 reference

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6 September 2017

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

1 reference

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Efficient adenoviral infection with IkappaB alpha reveals that macrophage tumor necrosis factor alpha production in rheumatoid arthritis is NF-kappaB dependent

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Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

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Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

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A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

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Thiol isomerases negatively regulate the cellular shedding activity of ADAM17.

1 reference

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14 September 2017

The cytoplasmic domains of TNFalpha-converting enzyme (TACE/ADAM17) and L-selectin are regulated differently by p38 MAPK and PKC to promote ectodomain shedding

1 reference

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14 September 2017

Exogenous nitric oxide inhibits shedding of ADAM17 substrates.

1 reference

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14 September 2017

Reactive oxygen species-dependent TNF-alpha converting enzyme activation through stimulation of 5-HT2B and alpha1D autoreceptors in neuronal cells

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ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

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Lipopolysaccharide induces matrix metalloproteinase-9 expression via a mitochondrial reactive oxygen species-p38 kinase-activator protein-1 pathway in Raw 264.7 cells

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TACE/ADAM-17 maturation and activation of sheddase activity require proprotein convertase activity.

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1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Allosteric disulfide bonds

1 reference

https://pubmed.ncbi.nlm.nih.gov/21865167

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of ADAM17 in the ectodomain shedding of TNF-alpha and its receptors by neutrophils and macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/21865167

12 December 2020

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inferred from PubMed ID database lookup

Redox regulation of beta2-integrin CD11b/CD18 activation

1 reference

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12 December 2020

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Inflammatory cytokine response in patients with septic shock secondary to generalized peritonitis

1 reference

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12 December 2020

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Desferrioxamine regulates tumor necrosis factor release in mesangial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21865167

12 December 2020

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Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion

1 reference

https://pubmed.ncbi.nlm.nih.gov/21865167

12 December 2020

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inferred from PubMed ID database lookup

Up-regulation of tumour necrosis factor-alpha receptors on monocytes by desferrioxamine

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

An essential role for ectodomain shedding in mammalian development

1 reference

https://pubmed.ncbi.nlm.nih.gov/21865167

12 December 2020

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inferred from PubMed ID database lookup

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10.1074/JBC.M111.277434

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11 February 2020

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11 February 2020

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11 February 2020

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