Towards clinical development of a Pfs48/45-based transmission blocking malaria vaccine (Q38775588)

6 September 2017

Towards clinical development of a Pfs48/45-based transmission blocking malaria vaccine (English)

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6 September 2017

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Michael Theisen

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Robert Sauerwein

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3

object named as

Robert Sauerwein

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6 September 2017

Matthijs M Jore

2

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6 September 2017

3 January 2017

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Expert Review of Vaccines

6 September 2017

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6 September 2017

16

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6 September 2017

329-336

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6 September 2017

4

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Impact of the large-scale deployment of artemether/lumefantrine on the malaria disease burden in Africa: case studies of South Africa, Zambia and Ethiopia

6 September 2017

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Changes in malaria indices between 1999 and 2007 in The Gambia: a retrospective analysis

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

A Research Agenda to Underpin Malaria Eradication

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Transmission blocking malaria vaccines

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Toward the development of effective transmission-blocking vaccines for malaria

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Recent advances in recombinant protein-based malaria vaccines

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Target antigens of transmission-blocking immunity on gametes of plasmodium falciparum

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Sequential expression of antigens on sexual stages of Plasmodium falciparum accessible to transmission-blocking antibodies in the mosquito

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Naturally acquired immunity to sexual stage P. falciparum parasites.

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

A Plasmodium falciparum 48/45 single epitope R0.6C subunit protein elicits high levels of transmission blocking antibodies

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

A multi-stage malaria vaccine candidate targeting both transmission and asexual parasite life-cycle stages

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Correctly folded Pfs48/45 protein of Plasmodium falciparum elicits malaria transmission-blocking immunity in mice

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Sexual differentiation in malaria parasites

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

A central role for P48/45 in malaria parasite male gamete fertility

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Cloning and expression of the gene coding for the transmission blocking target antigen Pfs48/45 of Plasmodium falciparum.

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Target antigens of malaria transmission blocking immunity exist as a stable membrane bound complex

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Malaria transmission-blocking antigen, Pfs230, mediates human red blood cell binding to exflagellating male parasites and oocyst production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

A potent malaria transmission blocking vaccine based on codon harmonized full length Pfs48/45 expressed in Escherichia coli

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Recombinant human antibodies specific for the Pfs48/45 protein of the malaria parasite Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

A longitudinal study of immune responses to Plasmodium falciparum sexual stage antigens in Tanzanian adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Naturally acquired immune responses to Plasmodium falciparum sexual stage antigens Pfs48/45 and Pfs230 in an area of seasonal transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Transmission-reducing immunity is inversely related to age in Plasmodium falciparum gametocyte carriers

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Prevalence of Plasmodium falciparum transmission reducing immunity among primary school children in a malaria moderate transmission region in Zimbabwe

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

The dynamics of naturally acquired immune responses to Plasmodium falciparum sexual stage antigens Pfs230 & Pfs48/45 in a low endemic area in Tanzania

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Naturally acquired antibody responses to recombinant Pfs230 and Pfs48/45 transmission blocking vaccine candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Plasmodium falciparum: membrane feeding assays and competition ELISAs for the measurement of transmission reduction in sera from Cameroon

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Association between anti-Pfs48/45 reactivity and P. falciparum transmission-blocking activity in sera from Cameroon

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Properties of epitopes of pfs 48/45, a target of transmission blocking monoclonal antibodies, on gametes of different isolates of plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Infectivity of cultured Plasmodium falciparum gametocytes to mosquitoes

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Epitope analysis of the malaria surface antigen pfs48/45 identifies a subdomain that elicits transmission blocking antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Predicted disulfide-bonded structures for three uniquely related proteins of Plasmodium falciparum, Pfs230, Pfs48/45 and Pf12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Extreme polymorphism in a vaccine antigen and risk of clinical malaria: implications for vaccine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Extreme geographical fixation of variation in the Plasmodium falciparum gamete surface protein gene Pfs48/45 compared with microsatellite loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Pooled Amplicon Deep Sequencing of Candidate Plasmodium falciparum Transmission-Blocking Vaccine Antigens

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Minimal variation in the transmission-blocking vaccine candidate Pfs48/45 of the human malaria parasite Plasmodium falciparum.

21 January 2018

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https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Protein disulfide isomerase assisted protein folding in malaria parasites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Plasmodium falciparum: heterologous synthesis of the transmission-blocking vaccine candidate Pfs48/45 in recombinant vaccinia virus-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Assembly and expression of a synthetic gene encoding the antigen Pfs48/45 of the human malaria parasite Plasmodium falciparum in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Heterologous expression of the C-terminal antigenic domain of the malaria vaccine candidate Pfs48/45 in the green algae Chlamydomonas reinhardtii

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Development of a single-replicon miniBYV vector for co-expression of heterologous proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

A Phase 1 study of the blood-stage malaria vaccine candidate AMA1-C1/Alhydrogel with CPG 7909, using two different formulations and dosing intervals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

In vitro studies with recombinant Plasmodium falciparum apical membrane antigen 1 (AMA1): production and activity of an AMA1 vaccine and generation of a multiallelic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Phase 1 trial of malaria transmission blocking vaccine candidates Pfs25 and Pvs25 formulated with montanide ISA 51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Immunological properties of recombinant proteins of the transmission blocking vaccine candidate, Pfs48/45, of the human malaria parasite Plasmodium falciparum produced in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Comparison of Intranasal Outer Membrane Vesicles with Cholera Toxin and Injected MF59C.1 as Adjuvants for Malaria Transmission Blocking Antigens AnAPN1 and Pfs48/45.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Comparative assessment of transmission-blocking vaccine candidates against Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Transmission-blocking activity of antibodies to Plasmodium falciparum GLURP.10C chimeric protein formulated in different adjuvants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Synthetic TLR4 agonists enhance functional antibodies and CD4+ T-cell responses against the Plasmodium falciparum GMZ2.6C multi-stage vaccine antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Protein folding in the bacterial periplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Electron avenue: pathways of disulfide bond formation and isomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

SHuffle, a novel Escherichia coli protein expression strain capable of correctly folding disulfide bonded proteins in its cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Pre-expression of a sulfhydryl oxidase significantly increases the yields of eukaryotic disulfide bond containing proteins expressed in the cytoplasm of E.coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Live recombinant vaccinia virus protects chimpanzees against hepatitis B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

21 January 2018

Vaccines against malaria

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Lactococcus lactis-based vaccines from laboratory bench to human use: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

A Plasmodium falciparum GLURP-MSP3 chimeric protein; expression in Lactococcus lactis, immunogenicity and induction of biologically active antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Reduced antibody responses against Plasmodium falciparum vaccine candidate antigens in the presence of Trichuris trichiura

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

A randomized controlled phase Ib trial of the malaria vaccine candidate GMZ2 in African children

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Safety and immunogenicity of the malaria vaccine candidate GMZ2 in malaria-exposed, adult individuals from Lambaréné, Gabon

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Safety and immunogenicity of GMZ2 - a MSP3-GLURP fusion protein malaria vaccine candidate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Bacterial superglue enables easy development of efficient virus-like particle based vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

Experimental human challenge infections can accelerate clinical malaria vaccine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2017.1276833

10.1080/14760584.2017.1276833

21 January 2018

Identifiers

DOI

1 reference

release_aqoxexhc7vdkrfvglwizwx4yui

6 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/aqoxexhc7vdkrfvglwizwx4yui

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

28043178

1 reference

PubMed ID

28043178