Molecular Targets of β-Lactam-Based Antimicrobials: Beyond the Usual Suspects (Q38792863)

6 September 2017

Molecular Targets of β-Lactam-Based Antimicrobials: Beyond the Usual Suspects (English)

1 reference

6 September 2017

Monika I Konaklieva

1

1 reference

6 September 2017

3 April 2014

1 reference

Antibiotics (Basel, Switzerland)

6 September 2017

1 reference

6 September 2017

3

1 reference

6 September 2017

2

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6 September 2017

128-142

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Creative Commons Attribution 4.0 International

6 September 2017

start time

3 April 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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6 September 2017

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Overcoming resistance to β-lactam antibiotics

6 September 2017

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Ceftazidime-avibactam: a novel cephalosporin/β-lactamase inhibitor combination

6 September 2017

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New β-lactam-β-lactamase inhibitor combinations in clinical development

6 September 2017

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β-lactamase-mediated resistance: a biochemical, epidemiological and genetic overview

6 September 2017

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Improving known classes of antibiotics: an optimistic approach for the future

6 September 2017

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Monocyclic β-lactams: new structures for new biological activities

6 September 2017

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Fix the antibiotics pipeline.

6 September 2017

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2-Azetidinone--a new profile of various pharmacological activities

6 September 2017

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The future of the β-lactams.

6 September 2017

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Beta-lactam antibiotics: from antibiosis to resistance and bacteriology

6 September 2017

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Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

6 September 2017

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N-thiolated beta-lactams: Studies on the mode of action and identification of a primary cellular target in Staphylococcus aureus

6 September 2017

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Bacterial resistance to beta-lactam antibiotics: compelling opportunism, compelling opportunity

6 September 2017

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Effect of aryl ring fluorination on the antibacterial properties of C4 aryl-substituted N-methylthio beta-lactams

6 September 2017

1 reference

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N-thiolated beta-lactams: novel antibacterial agents for methicillin-resistant Staphylococcus aureus

6 September 2017

1 reference

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Molecular markers of serine protease evolution

6 September 2017

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Sequence determinants of function and evolution in serine proteases.

6 September 2017

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Molecular basis of antibiotic resistance and beta-lactamase inhibition by mechanism-based inactivators: perspectives and future directions

6 September 2017

1 reference

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The reactivity of beta-lactams, the mechanism of catalysis and the inhibition of beta-lactamases

6 September 2017

1 reference

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Beta-lactamases and beta-lactamase inhibitors

6 September 2017

1 reference

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Kinship and diversification of bacterial penicillin-binding proteins and beta-lactamases

6 September 2017

1 reference

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Evolutionary families of peptidases

6 September 2017

1 reference

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Cloning and sequencing of thiol-specific antioxidant from mammalian brain: alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes

6 September 2017

1 reference

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Families and clans of serine peptidases

6 September 2017

1 reference

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A functional classification scheme for beta-lactamases and its correlation with molecular structure

6 September 2017

1 reference

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beta-Lactamase-catalyzed hydrolysis of acyclic depsipeptides and acyl transfer to specific amino acid acceptors

6 September 2017

1 reference

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Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine

6 September 2017

1 reference

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Excitement in the beta-lactamase arena

6 September 2017

1 reference

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Classification of beta-lactamases: groups 1, 2a, 2b, and 2b'.

6 September 2017

1 reference

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The crisis in antibiotic resistance

6 September 2017

1 reference

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beta-Lactam resistance in gram-negative bacteria: global trends and clinical impact

6 September 2017

1 reference

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Export of protein: a biochemical view

6 September 2017

1 reference

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4 Functional Modifications and Nuclear Analogues of β -Lactam Antibiotics -Part II

14 September 2017

1 reference

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Global regulatory impact of ClpP protease of Staphylococcus aureus on regulons involved in virulence, oxidative stress response, autolysis, and DNA repair

14 September 2017

1 reference

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Pilus and nonpilus bacterial adhesins: assembly and function in cell recognition

14 September 2017

1 reference

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Evolution and dissemination of beta-lactamases accelerated by generations of beta-lactam antibiotics

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4790389

Tertiary structural similarity between a class A beta-lactamase and a penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4790389

On the origin of bacterial resistance to penicillin: comparison of a beta-lactamase and a penicillin target

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4790389

C4-alkylthiols with activity against Moraxella catarrhalis and Mycobacterium tuberculosis

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4790389

The acyl-enzyme mechanism of beta-lactamase action. The evidence for class C Beta-lactamases

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4790389

The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4790389

Mode of interaction between beta-lactam antibiotics and the exocellular DD-carboxypeptidase--transpeptidase from Streptomyces R39

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4790389

Monocyclic β-lactams as antibacterial agents: facing antioxidant activity of N-methylthio-azetidinones.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4790389

Reliable determination of amidicity in acyclic amides and lactams

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4790389

Azetidinones as zinc-binding groups to design selective HDAC8 inhibitors

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4790389

Beta-lactam probes as selective chemical-proteomic tools for the identification and functional characterization of resistance associated enzymes in MRSA.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4790389

Beta-lactams as selective chemical probes for the in vivo labeling of bacterial enzymes involved in cell wall biosynthesis, antibiotic resistance, and virulence.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4790389

A quantitative scale for the extent of conjugation of the amide bond. Amidity percentage as a chemical driving force

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4790389

Peptidase activity of beta-lactamases.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4790389

The First Structural and Mechanistic Insights for Class D β-Lactamases: Evidence for a Novel Catalytic Process for Turnover of β-Lactam Antibiotics

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FANTIBIOTICS3020128

Beta-lactamase inhibitors: agents to overcome bacterial resistance

21 January 2018

1 reference

12 December 2020

Stereoselective Synthesis of Optically Active β-Lactams, Potential Inhibitors of Pilus Assembly in Pathogenic Bacteria

1 reference

12 December 2020

Resistance to antibiotics

1 reference

12 December 2020

Systemic energy management by strategically located functional components within molecular frameworks, determined by systems chemistry

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12 December 2020

Amidicity change as a significant driving force and thermodynamic selection rule of transamidation reactions. A synergy between experiment and theory

1 reference

12 December 2020

Determination of the kinetic parameters of Escherichia coli leader peptidase activity using a continuous assay: the pH dependence and time-dependent inhibition by beta-lactams are consistent with a novel serine protease mechanism

1 reference

12 December 2020

Recent advances in the chemistry of natural products

1 reference

12 December 2020

10.3390/ANTIBIOTICS3020128

Identifiers

DOI

1 reference

release_m5xxij7dgnflra4x5vlto32f2y

6 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/m5xxij7dgnflra4x5vlto32f2y

24 November 2022

mapped directly with Wikidata item

PMCID

4790389

1 reference

6 September 2017

1 reference

PMCID

4790389