Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties (Q24674719)

1

0 references

Srinivas Kodali

2

0 references

Sang Ho Lee

3

0 references

Andrew Galgoci

4

0 references

Ronald Painter

5

0 references

Karen Dorso

6

0 references

Fred Racine

7

0 references

Mary Motyl

8

0 references

Lorraine Hernandez

9

0 references

Elizabeth Tinney

10

0 references

Steven L Colletti

11

0 references

Kithsiri Herath

12

0 references

Richard Cummings

13

0 references

Oscar Salazar

14

0 references

Ignacio González

15

0 references

Angela Basilio

16

0 references

Francisca Vicente

17

0 references

Fernando Pelaez

19

0 references

Hiranthi Jayasuriya

20

0 references

Katherine Young

21

0 references

Doris F Cully

22

0 references

Sheo B Singh

Proceedings of the National Academy of Sciences of the United States of America

23

0 references

language of work or name

English

0 references

publication date

1 May 2007

0 references

published in

0 references

volume

104

0 references

issue

18

0 references

page(s)

7612-6

0 references

cites work

Discovery of FabH/FabF inhibitors from natural products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Essential Bacillus subtilis genes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

THE STRUCTURAL BIOLOGY OF TYPE II FATTY ACID BIOSYNTHESIS

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

First X-ray cocrystal structure of a bacterial FabH condensing enzyme and a small molecule inhibitor achieved using rational design and homology modeling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Structural and functional organization of the animal fatty acid synthase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Global transposon mutagenesis and a minimal Mycoplasma genome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Multi-targeting by monotherapeutic antibacterials.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Empirical antibacterial drug discovery--foundation in natural products

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Determination of selectivity and efficacy of fatty acid synthesis inhibitors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Fatty acid biosynthesis as a target for novel antibacterials

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Lipid biosynthesis as a target for antibacterial agents

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Bacterial fatty acid biosynthesis: targets for antibacterial drug discovery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Beta-ketoacyl acyl carrier protein synthase III (FabH) is essential for fatty acid biosynthesis in Streptomyces coelicolor A3(2).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Response of Bacillus subtilis to cerulenin and acquisition of resistance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Increased antifungal activity of L-733,560, a water-soluble, semisynthetic pneumocandin, is due to enhanced inhibition of cell wall synthesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Leakage of periplasmic enzymes from envA1 strains of Escherichia coli

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Overproduction of beta-ketoacyl-acyl carrier protein synthase I imparts thiolactomycin resistance to Escherichia coli K-12

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

β-Ketoacyl-Acyl Carrier Protein Synthase III (FabH) Is Essential for Bacterial Fatty Acid Synthesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Thiolactomycin, a new antibiotic. III. In vitro antibacterial activity.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

beta-Ketoacyl-ACP synthase I of Escherichia coli: nucleotide sequence of the fabB gene and identification of the cerulenin binding residue.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Discovery of a small molecule that inhibits cell division by blocking FtsZ, a novel therapeutic target of antibiotics

19 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0700746104

Thiotetromycin, a new antibiotic. Taxonomy, production, isolation, and physicochemical and biological properties.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1863502

Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy

28 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0700746104

Isolation and structure of antibiotic U-68,204, a new thiolactone

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17456595

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

STUDIES ON CERULENIN. IV. BIOLOGICAL CHARACTERISTICS OF CERULENIN

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17456595

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0700746104

1 reference

3142202

ADS bibcode

2007PNAS..104.7612W

0 references

3142202

1 reference

1 reference

1 reference