Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1-Transfected Human Embryonic Kidney 293 Cells. (Q38809316)

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scientific article published on 23 December 2015

Language	Label	Description	Also known as
English	Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1-Transfected Human Embryonic Kidney 293 Cells.	scientific article published on 23 December 2015

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scholarly article

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3 March 2020

Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1-Transfected Human Embryonic Kidney 293 Cells (English)

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3 March 2020

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inferred from title

4

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3 March 2020

Dennis O. Scott

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3 March 2020

author name string

Huan-Chieh Chien

1

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3 March 2020

Arik A Zur

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3 March 2020

Tristan S Maurer

3

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John Tolsma

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Paul Jasper

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3 March 2020

Kathleen M Giacomini

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publication date

23 December 2015

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Drug Metabolism and Disposition

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44

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356-364

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3 March 2020

3

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Intracellular concentrations determine the cytotoxicity of adefovir, cidofovir and tenofovir

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Intracellular drug concentrations

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The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin.

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Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

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Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

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Measurement of intracellular volume in monolayers of cultured cells

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10.1124/DMD.115.066647

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3 March 2020

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3 March 2020

1 reference

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