Mechanism of metformin action in MCF-7 and MDA-MB-231 human breast cancer cells involves oxidative stress generation, DNA damage, and transforming growth factor β1 induction. (Q38819985)

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scientific article published on 11 November 2015

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English	Mechanism of metformin action in MCF-7 and MDA-MB-231 human breast cancer cells involves oxidative stress generation, DNA damage, and transforming growth factor β1 induction.	scientific article published on 11 November 2015

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29 February 2020

Mechanism of metformin action in MCF-7 and MDA-MB-231 human breast cancer cells involves oxidative stress generation, DNA damage, and transforming growth factor β1 induction (English)

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29 February 2020

Fernando H Borges

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29 February 2020

Flávia A Guarnier

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Julio Cesar Madureira de Freitas

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29 February 2020

Alessandra L Cecchini

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Poliana Camila Marinello

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Thamara Nishida Xavier da Silva

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Amanda Fouto Neves

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Kaliana Larissa Machado

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Sara Santos Bernardes

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José Andrés Morgado-Díaz

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29 February 2020

Rodrigo Cabral Luiz

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Rubens Cecchini

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29 February 2020

Alessandra Lourenço Cecchini

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publication date

11 November 2015

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29 February 2020

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29 February 2020

5337-5346

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29 February 2020

https://scigraph.springernature.com/pub.10.1007/s13277-015-4395-x

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Demographic and clinico-pathological characteristics in patients with invasive breast cancer receiving metformin.

1 reference

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21 January 2018

Metformin in cancer: translational challenges

1 reference

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21 January 2018

Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells

1 reference

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21 January 2018

Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells

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21 January 2018

Metformin decreases circulating androgen and estrogen levels in nondiabetic women with breast cancer.

1 reference

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21 January 2018

Antidiabetic drug metformin induces apoptosis in human MCF breast cancer via targeting ERK signaling

1 reference

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21 January 2018

Lipid peroxidation, oxidative stress genes and dietary factors in breast cancer protection: a hypothesis

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21 January 2018

Oxidative stress and hematological profiles of advanced breast cancer patients subjected to paclitaxel or doxorubicin chemotherapy.

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21 January 2018

Metformin induces apoptosis and cell cycle arrest mediated by oxidative stress, AMPK and FOXO3a in MCF-7 breast cancer cells

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21 January 2018

Nonfamilial breast cancer subtypes

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21 January 2018

Differences in breast carcinoma characteristics in newly diagnosed African-American and Caucasian patients: a single-institution compilation compared with the National Cancer Institute's Surveillance, Epidemiology, and End Results database

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21 January 2018

Transforming growth factor-beta in breast cancer: too much, too late

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21 January 2018

Targeting the PI3K-Akt pathway in human cancer: rationale and promise

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21 January 2018

An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

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21 January 2018

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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21 January 2018

Effects of an Indolocarbazole-Derived CDK4 Inhibitor on Breast Cancer Cells

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21 January 2018

Catalase in vitro

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21 January 2018

Decreased oxidant profile and increased antioxidant capacity in naturally postmenopausal women.

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21 January 2018

Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

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21 January 2018

New molecules and old drugs as emerging approaches to selectively target human glioblastoma cancer stem cells

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21 January 2018

Response of breast cancer cells and cancer stem cells to metformin and hyperthermia alone or combined

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21 January 2018

Metformin: a therapeutic opportunity in breast cancer

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21 January 2018

Metformin induces both caspase-dependent and poly(ADP-ribose) polymerase-dependent cell death in breast cancer cells

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21 January 2018

Effects of metformin on breast cancer cell proliferation, the AMPK pathway and the cell cycle

1 reference

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21 January 2018

The anti-proliferative effect of metformin in triple-negative MDA-MB-231 breast cancer cells is highly dependent on glucose concentration: implications for cancer therapy and prevention.

1 reference

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21 January 2018

p53 as an intervention target for cancer and aging

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21 January 2018

The coordinate regulation of the p53 and mTOR pathways in cells

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Targeting the MAPK-RAS-RAF signaling pathway in cancer therapy

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Superoxide radicals increase transforming growth factor-beta1 and collagen release from human lung fibroblasts via cellular influx through chloride channels

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21 January 2018

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10.1007/S13277-015-4395-X

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29 February 2020

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29 February 2020

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