Metformin induces apoptosis and cell cycle arrest mediated by oxidative stress, AMPK and FOXO3a in MCF-7 breast cancer cells (Q28539104)

1

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Stephanie Puukila

2

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Rosangela Eichler

3

0 references

Sandra C Sampaio

4

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Heidi L Forsyth

5

0 references

Simon J Lees

6

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Aneli M Barbosa

7

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Robert F H Dekker

8

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Zuleica B Fortes

9

0 references

Neelam Khaper

Creative Commons Attribution 4.0 International

10

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language of work or name

English

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publication date

2014

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published in

PLOS One

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volume

9

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issue

5

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page(s)

e98207

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copyright license

start time

23 May 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Metformin and reduced risk of cancer in diabetic patients

7 April 2017

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Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor

29 September 2017

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Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth

29 September 2017

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29 September 2017

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29 September 2017

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A comparison of the effects of thiazolidinediones and metformin on metabolic control in patients with type 2 diabetes mellitus

29 September 2017

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Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

29 September 2017

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29 September 2017

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21 January 2018

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The mitochondrion in apoptosis: how Pandora's box opens

29 September 2017

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29 September 2017

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Nutrition, hormones, and breast cancer: is insulin the missing link?

29 September 2017

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29 September 2017

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A simple colorimetric method for the measurement of hydrogen peroxide produced by cells in culture

3 June 2018

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Rapid microassays for the measurement of superoxide and hydrogen peroxide production by macrophages in culture using an automatic enzyme immunoassay reader

3 June 2018

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Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin

3 June 2018

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Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth

21 January 2018

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The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase

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p21(Cip1) expression is increased in ambient oxygen, compared to estimated physiological (5%) levels in rat muscle precursor cell culture

21 January 2018

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Metformin: new understandings, new uses

21 January 2018

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Long-lived Drosophila with overexpressed dFOXO in adult fat body

21 January 2018

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Sphingosine generation, cytochrome c release, and activation of caspase-7 in doxorubicin-induced apoptosis of MCF7 breast adenocarcinoma cells.

21 January 2018

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Cancer: Sacrifice for survival.

21 January 2018

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A central role for neuronal adenosine 5'-monophosphate-activated protein kinase in cancer-induced anorexia

21 January 2018

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12 December 2020

Emerging targets for anti-inflammatory therapy

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12 December 2020

Increased cell growth and tumorigenicity in human prostate LNCaP cells by overexpression to cyclin D1

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12 December 2020

Establishing long-term cultures of mammalian normal, solid tumor, and ascites tumor cells on glass

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12 December 2020

Metformin reduces the stimulatory effect of obesity on in vivo Walker-256 tumor development and increases the area of tumor necrosis

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12 December 2020

10.1371/JOURNAL.PONE.0098207

Identifiers

DOI

1 reference

ADS bibcode

2014PLoSO...998207Q

0 references

1 reference

1 reference

PubMed publication ID

24858012

1 reference